Details for: Tpmt

Gene ID: 22017

Symbol: Tpmt

Ensembl ID: ENSMUSG00000021376

Description: thiopurine methyltransferase

Associated with

Other Information

Genular Protein ID: 3490971968

Symbol: TPMT_MOUSE

Name: Thiopurine methyltransferase

UniProtKB Accession Codes:

O55060 Q9JIL7 Q9QUG7

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 EC 2 EMBL 13 EvolutionaryTrace 1 GO 5 Gene3D 1 HAMAP 1 InParanoid 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 3 PIRSF 1 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 1 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9539138

Title: Molecular cloning and functional characterization of the cDNA encoding the murine thiopurine S-methyltransferase (TPMT).

PubMed ID: 9539138

DOI: 10.1016/s0014-5793(98)00159-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 18484748

Title: Structural basis of substrate recognition in thiopurine S-methyltransferase.

PubMed ID: 18484748

DOI: 10.1021/bi800102x

Sequence Information:

  • Length: 240
  • Mass: 27586
  • Checksum: 2BA57F30E8EB72D2
  • Sequence:
    • MSLDMKEHPD AEVQKNQVLT LEDWKEKWVT RHISFHQEQG HQLLKKHLDT FLKGQSGLRV 
FFPLCGKAIE MKWFADRGHT VVGVEISEIG IREFFAEQNL SYTEEPLAEI AGAKVFKSSS 
GSISLYCCSI FDLPRANIGK FDRIWDRGAL VAINPGDHDR YADIILSLLR KEFQYLVAVL 
SYDPTKHAGP PFYVPSAELK RLFGTKCSMQ CLEEVDALEE RHKAWGLDYL FEKLYLLTEK

Genular Protein ID: 2383289484

Symbol: A0A0R4J018_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0R4J018

Database IDs:

AGR 1 ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 5 ChiTaRS 1 DNASU 1 EC 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HAMAP 1 InterPro 3 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PROSITE 1 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 SMR 1 SUPFAM 1 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 240
  • Mass: 27572
  • Checksum: EA6274536AED68A0
  • Sequence:
    • MSLDMKEHPD AEVQKNQVLT LEDWKEKWVT RHISFHQEQG HQLLKKHLDT FLKGQSGLRV 
FFPLCGKAVE MKWFADRGHT VVGVEISEIG IREFFAEQNL SYTEEPLAEI AGAKVFKSSS 
GSISLYCCSI FDLPRANIGK FDRIWDRGAL VAINPGDHDR YADIILSLLR KEFQYLVAVL 
SYDPTKHAGP PFYVPSAELK RLFGTKCSMQ CLEEVDALEE RHKAWGLDYL FEKLYLLTEK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.