Genular: Defining Cellular Identity and Function

Details for: Tpo

Gene ID: 22018

Symbol: Tpo

Ensembl ID: ENSMUSG00000020673

Description: thyroid peroxidase

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of amine-derived hormones
(R-MMU-209776)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Thyroxine biosynthesis
(R-MMU-209968)
Calcium ion binding
(GO:0005509)
Cell surface
(GO:0009986)
Embryonic hemopoiesis
(GO:0035162)
Extracellular space
(GO:0005615)
Heme binding
(GO:0020037)
Hormone biosynthetic process
(GO:0042446)
Hydrogen peroxide catabolic process
(GO:0042744)
Iodide peroxidase activity
(GO:0004447)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Oxidoreductase activity
(GO:0016491)
Peroxidase activity
(GO:0004601)
Response to oxidative stress
(GO:0006979)
Thyroid hormone generation
(GO:0006590)

Other Information

Proteins

Thyroid peroxidase

Genular Protein ID: 186188398

Symbol: PERT_MOUSE

Name: Thyroid peroxidase

UniProtKB Accession Codes:

P35419 Q8C8B1

Database IDs:

Citations:

PubMed ID: 7916704

Title: Nucleotide sequence of the cDNA encoding mouse thyroid peroxidase.

PubMed ID: 7916704

DOI: 10.1016/0378-1119(93)90141-o

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

Sequence Information:

Length: 914
Mass: 101342
Checksum: 595E9A0B71F3DD01
Sequence:

MRTLGAMAIM LVVMGTVIFL SFILRSRDIL CGKTMKSHVI SAVETSQLMV DHAVYNTMKR 
NLKKREVLSP AQLLSFFKLP ESTSGAISRA AEIMETSIQV MKREQSQFST DALSADILGT 
IANLSGCLPF MLPPRCPDTC LANKYRPITG ACNNRDHPRW GASNTALARW LPPVYEDGFS 
QPKGWNPNFL YHGFPLPPVR EVTRHLIQVS NEAVTEDDQY SDFLPVWGQY IDHDIALTPQ 
STSTAAFWGG VDCQLTCENQ NPCFPIQLPS NSSGTTACLP FYRSSAACGT GDQGALFGNL 
SAANPRQQMN GLTSFLDAST VYGSSPGVEK QLRNWSSSAG LLRVNTLHLD AGRAYLPFAT 
AACAPEPGTP RTNRTPCFLA GDGRASEVPA LAAVHTLWLR EHNRLASAFK AINKHWSANT 
AYQEARKVVG ALHQIITMRD YIPKILGPDA FRQYVGPYEG YNPTVNPTVS NIFSTAAFRF 
GHATVHPLVR RLNTDFQEHT ELPRLQLRDV FFRPWRLIQE GGLDPIVRGL LARAAKLQVQ 
GQLMNEELTE RLFVLSNVGT LDLASLNLQR GRDHGLPDYN EWREFCGLSR LETPAELNKA 
IANRSMVNKI MDLYKHADNI DVWLGGLAEK FLPGARTGPL FACIIGKQMK ALRDGDRFWW 
ENTNVFTDAQ RQELEKHSLP RVICDNTGLT RVPVDAFRIG KFPQDFESCE DIPSMDLELW 
RETFPQDDKC VFPEEVDNGN FVHCEESGKL VLVYSCFHGY KLQGQEQVTC TQKGWDSEPP 
VCKDVNECAD LTHPPCHPSA QCKNTKGSFQ CVCTDPYVLG EDEKTCIDSG RLPRASWVSI 
ALGALLIGGL ASLTWIVICR WTHADKKATL PITERVTTQS GCRKSQGRGI SPHKAAAQDT 
GQEPASGSRV LLCE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.