Details for: Nr2c1
Associated with
Other Information
Genular Protein ID: 4047889601
Symbol: NR2C1_MOUSE
Name: Nuclear receptor subfamily 2 group C member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8595902
Title: Genomic structure, promoter identification, and chromosomal mapping of a mouse nuclear orphan receptor expressed in embryos and adult testes.
PubMed ID: 8595902
PubMed ID: 8858600
Title: Molecular cloning and characterization of a mouse nuclear orphan receptor expressed in embryos and testes.
PubMed ID: 8858600
DOI: 10.1002/(sici)1098-2795(199607)44:3<305::aid-mrd4>3.0.co;2-q
PubMed ID: 9071982
Title: Distinct expression patterns and biological activities of two isoforms of the mouse orphan receptor TR2.
PubMed ID: 9071982
PubMed ID: 9504722
Title: Polymorphism in the murine Tr2-11 gene encoding an orphan receptor, and its exclusion as a candidate gene for the cataract mutation Cat3.
PubMed ID: 9504722
PubMed ID: 9694834
Title: A bidirectional regulation between the TR2/TR4 orphan receptors (TR2/TR4) and the ciliary neurotrophic factor (CNTF) signaling pathway.
PubMed ID: 9694834
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8530418
Title: Multiple functions of the TR2-11 orphan receptor in modulating activation of two key cis-acting elements involved in the retinoic acid signal transduction system.
PubMed ID: 8530418
PubMed ID: 9369481
Title: The orphan nuclear receptor TR2 suppresses a DR4 hormone response element of the mouse CRABP-I gene promoter.
PubMed ID: 9369481
DOI: 10.1021/bi971598z
PubMed ID: 9774688
Title: Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.
PubMed ID: 9774688
PubMed ID: 11463856
Title: The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases.
PubMed ID: 11463856
PubMed ID: 12093744
Title: An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer.
PubMed ID: 12093744
DOI: 10.1093/emboj/cdf340
PubMed ID: 12052874
Title: Spermatogenesis and testis development are normal in mice lacking testicular orphan nuclear receptor 2.
PubMed ID: 12052874
PubMed ID: 16130175
Title: Protein kinase C-mediated phosphorylation of orphan nuclear receptor TR2: effects on receptor stability and activity.
PubMed ID: 16130175
PubMed ID: 16317770
Title: Ligand-independent orphan receptor TR2 activation by phosphorylation at the DNA-binding domain.
PubMed ID: 16317770
PubMed ID: 17431400
Title: Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.
PubMed ID: 17431400
PubMed ID: 17974920
Title: The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.
PubMed ID: 17974920
DOI: 10.1101/gad.1593307
PubMed ID: 17187077
Title: SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells.
PubMed ID: 17187077
DOI: 10.1038/nsmb1185
PubMed ID: 17389641
Title: Orphan nuclear receptor TR2, a mediator of preadipocyte proliferation, is differentially regulated by RA through exchange of coactivator PCAF with corepressor RIP140 on a platform molecule GRIP1.
PubMed ID: 17389641
DOI: 10.1093/nar/gkl1147
PubMed ID: 18682553
Title: Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression.
PubMed ID: 18682553
PubMed ID: 19131575
Title: Roles of testicular orphan nuclear receptors 2 and 4 in early embryonic development and embryonic stem cells.
PubMed ID: 19131575
DOI: 10.1210/en.2008-1165
PubMed ID: 19204783
Title: HDAC3 as a molecular chaperone for shuttling phosphorylated TR2 to PML: a novel deacetylase activity-independent function of HDAC3.
PubMed ID: 19204783
Sequence Information:
- Length: 590
- Mass: 65476
- Checksum: E639AF3E5312918D
- Sequence:
MATIEEIAHQ IIDQQMGEIV TEQQTGQKIQ IVTALDHSTQ GKQFILANHE GSTPGKVFLT TPDAAGVNQL FFTSPDLSAP HLQLLTEKSP DQGPNKVFDL CVVCGDKASG RHYGAITCEG CKGFFKRSIR KNLVYSCRGS KDCVINKHHR NRCQYCRLQR CIAFGMKQDS VQCERKPIEV SREKSSNCAA STEKIYIRKD LRSPLAATPT FVTDSETARS AGLLDSGMFV NIHPSGIKTE PAMLMAPDKA ESCQGDLSTL ASVVTSLANL GKAKDLSHCG GDMPVVQSLR NGDTSFGAFH HDIQTNGDVS RAFDTLAKAL TPGESSACQS PEEGMEGSPH LIAGEPSFVE KEGPLLSESH VAFRLTMPSP MPEYLNVHYI GESASRLLFL SMHWALSIPS FQALGQENSI SLVKAYWNEL FTLGLAQCWQ VMNVATILAT FVNCLHSSLQ QDKMSPERRK SLMEHIFKLQ EFCNSMVKLC IDGHEYAYLK AIVLFSPDHP GLENMELIER FQEKAYVEFQ DYITRTYPDD TYRLSRLLLR LPALRLMNAT ITEELFFKGL IGNVRIDSVI PHILKMEPAD YNSQIIGHSL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.