Genular: Defining Cellular Identity and Function

Details for: Hsp90b1

Gene ID: 22027

Symbol: Hsp90b1

Ensembl ID: ENSMUSG00000020048

Description: heat shock protein 90, beta (Grp94), member 1

Associated with

Binding and uptake of ligands by scavenger receptors
(R-MMU-2173782)
Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interleukin-4 and interleukin-13 signaling
(R-MMU-6785807)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Scavenging by class a receptors
(R-MMU-3000480)
Signaling by interleukins
(R-MMU-449147)
Toll-like receptor cascades
(R-MMU-168898)
Trafficking and processing of endosomal tlr
(R-MMU-1679131)
Vesicle-mediated transport
(R-MMU-5653656)
Actin rod assembly
(GO:0031247)
Atp-dependent protein folding chaperone
(GO:0140662)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cellular response to atp
(GO:0071318)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum chaperone complex
(GO:0034663)
Endoplasmic reticulum lumen
(GO:0005788)
Endoplasmic reticulum membrane
(GO:0005789)
Erad pathway
(GO:0036503)
Extracellular region
(GO:0005576)
Insulin processing
(GO:0030070)
Low-density lipoprotein particle receptor binding
(GO:0050750)
Midbody
(GO:0030496)
Nucleotide binding
(GO:0000166)
Perinuclear region of cytoplasm
(GO:0048471)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Protein folding chaperone
(GO:0044183)
Protein phosphatase binding
(GO:0019903)
Regulation of phosphoprotein phosphatase activity
(GO:0043666)
Rna binding
(GO:0003723)
Sarcoplasmic reticulum
(GO:0016529)
Smooth endoplasmic reticulum
(GO:0005790)
Sperm plasma membrane
(GO:0097524)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

Endoplasmin

Genular Protein ID: 3615175614

Symbol: ENPL_MOUSE

Name: Endoplasmin

UniProtKB Accession Codes:

P08113 P11427

Database IDs:

Citations:

PubMed ID: 3036833

Title: ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp90) and the 94-kDa glucose regulated protein (GRP94).

PubMed ID: 3036833

DOI: 10.1016/s0021-9258(18)47496-0

PubMed ID: 3612811

Title: Isolation and identification of partial cDNA clones for endoplasmin, the major glycoprotein of mammalian endoplasmic reticulum.

PubMed ID: 3612811

DOI: 10.1016/0022-2836(87)90381-0

PubMed ID: 2438686

Title: 5'-structural analysis of genes encoding polymorphic antigens of chemically induced tumors.

PubMed ID: 2438686

DOI: 10.1073/pnas.84.11.3807

PubMed ID: 2768254

Title: HSP100, a 100-kDa heat shock protein, is a Ca2+-calmodulin-regulated actin-binding protein.

PubMed ID: 2768254

DOI: 10.1016/s0021-9258(18)63814-1

PubMed ID: 8179819

Title: Analysis of the structure and synthesis of GRP94, an abundant stress protein of the endoplasmic reticulum.

PubMed ID: 8179819

DOI: 10.1089/dna.1994.13.117

PubMed ID: 12475965

Title: A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.

PubMed ID: 12475965

DOI: 10.1091/mbc.e02-05-0311

PubMed ID: 16931514

Title: Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver.

PubMed ID: 16931514

DOI: 10.1074/jbc.m605701200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21093319

Title: Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells.

PubMed ID: 21093319

DOI: 10.1016/j.immuni.2010.11.013

PubMed ID: 20865800

Title: Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone.

PubMed ID: 20865800

DOI: 10.1038/ncomms1070

PubMed ID: 17525271

Title: Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases.

PubMed ID: 17525271

DOI: 10.2353/ajpath.2007.061266

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 802
Mass: 92476
Checksum: BDF33B9BD86BFC5F
Sequence:

MRVLWVLGLC CVLLTFGFVR ADDEVDVDGT VEEDLGKSRE GSRTDDEVVQ REEEAIQLDG 
LNASQIRELR EKSEKFAFQA EVNRMMKLII NSLYKNKEIF LRELISNASD ALDKIRLISL 
TDENALAGNE ELTVKIKCDK EKNLLHVTDT GVGMTREELV KNLGTIAKSG TSEFLNKMTE 
AQEDGQSTSE LIGQFGVGFY SAFLVADKVI VTSKHNNDTQ HIWESDSNEF SVIADPRGNT 
LGRGTTITLV LKEEASDYLE LDTIKNLVRK YSQFINFPIY VWSSKTETVE EPLEEDEAAK 
EEKEESDDEA AVEEEEEEKK PKTKKVEKTV WDWELMNDIK PIWQRPSKEV EEDEYKAFYK 
SFSKESDDPM AYIHFTAEGE VTFKSILFVP TSAPRGLFDE YGSKKSDYIK LYVRRVFITD 
DFHDMMPKYL NFVKGVVDSD DLPLNVSRET LQQHKLLKVI RKKLVRKTLD MIKKIADEKY 
NDTFWKEFGT NIKLGVIEDH SNRTRLAKLL RFQSSHHSTD ITSLDQYVER MKEKQDKIYF 
MAGSSRKEAE SSPFVERLLK KGYEVIYLTE PVDEYCIQAL PEFDGKRFQN VAKEGVKFDE 
SEKTKESREA TEKEFEPLLN WMKDKALKDK IEKAVVSQRL TESPCALVAS QYGWSGNMER 
IMKAQAYQTG KDISTNYYAS QKKTFEINPR HPLIRDMLRR IKEDEDDKTV MDLAVVLFET 
ATLRSGYLLP DTKAYGDRIE RMLRLSLNID PEAQVEEEPE EEPEDTSEDA EDSEQDEGEE 
MDAGTEEEEE ETEKESTEKD EL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hsp90b1

Associated with

Other Information

ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp90) and the 94-kDa glucose regulated protein (GRP94). PubMed ID: 3036833

Isolation and identification of partial cDNA clones for endoplasmin, the major glycoprotein of mammalian endoplasmic reticulum. PubMed ID: 3612811

5'-structural analysis of genes encoding polymorphic antigens of chemically induced tumors. PubMed ID: 2438686

HSP100, a 100-kDa heat shock protein, is a Ca2+-calmodulin-regulated actin-binding protein. PubMed ID: 2768254

Analysis of the structure and synthesis of GRP94, an abundant stress protein of the endoplasmic reticulum. PubMed ID: 8179819

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. PubMed ID: 12475965

Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver. PubMed ID: 16931514

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. PubMed ID: 21093319

Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone. PubMed ID: 20865800

Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases. PubMed ID: 17525271

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337