Genular: Defining Cellular Identity and Function

Details for: Traf5

Gene ID: 22033

Symbol: Traf5

Ensembl ID: ENSMUSG00000026637

Description: TNF receptor-associated factor 5

Associated with

Apoptotic process
(GO:0006915)
Cd40 receptor complex
(GO:0035631)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
Identical protein binding
(GO:0042802)
Interleukin-17-mediated signaling pathway
(GO:0097400)
Metal ion binding
(GO:0046872)
Mrna stabilization
(GO:0048255)
Plasma membrane signaling receptor complex
(GO:0098802)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Protein binding
(GO:0005515)
Protein k63-linked ubiquitination
(GO:0070534)
Regulation of apoptotic process
(GO:0042981)
Regulation of canonical nf-kappab signal transduction
(GO:0043122)
Signal transduction
(GO:0007165)
Signal transduction involved in regulation of gene expression
(GO:0023019)
Thioesterase binding
(GO:0031996)
Tumor necrosis factor-mediated signaling pathway
(GO:0033209)
Tumor necrosis factor receptor binding
(GO:0005164)
Ubiquitin protein ligase binding
(GO:0031625)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

TNF receptor-associated factor 5

Genular Protein ID: 3154400507

Symbol: TRAF5_MOUSE

Name: TNF receptor-associated factor 5

UniProtKB Accession Codes:

P70191 Q61480

Database IDs:

Citations:

PubMed ID: 8663299

Title: TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.

PubMed ID: 8663299

DOI: 10.1074/jbc.271.25.14661

PubMed ID: 8790348

Title: TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.

PubMed ID: 8790348

DOI: 10.1073/pnas.93.18.9437

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15121867

Title: TRAF family proteins link PKR with NF-kappa B activation.

PubMed ID: 15121867

DOI: 10.1128/mcb.24.10.4502-4512.2004

PubMed ID: 23542741

Title: A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.

PubMed ID: 23542741

DOI: 10.1038/ni.2565

Sequence Information:

Length: 558
Mass: 64145
Checksum: 48F64FB83BD587E5
Sequence:

MAHSEEQAAV PCAFIRQNSG NSISLDFEPD TEYQFVEQLE ERYKCAFCHS VLHNPHQTGC 
GHRFCQQCIR SLRELNSVPI CPVDKEVIKP QEVFKDNCCK REVLNLHVYC KNAPGCNARI 
ILGRFQDHLQ HCSFQAVPCP NESCREAMLR KDVKEHLSAY CRFREEKCLY CKRDIVVTNL 
QDHEENSCPA YPVSCPNRCV QTIPRARVNE HLTVCPEAEQ DCPFKHYGCT VKGKRGNLLE 
HERAALQDHM LLVLEKNYQL EQRISDLYQS LEQKESKIQQ LAETVKKFEK ELKQFTQMFG 
RNGTFLSNVQ ALTSHTDKSA WLEAQVRQLL QIVNQQPSRL DLRSLVDAVD SVKQRITQLE 
ASDQRLVLLE GETSKHDAHI NIHKAQLNKN EERFKQLEGA CYSGKLIWKV TDYRVKKREA 
VEGHTVSVFS QPFYTSRCGY RLCARAYLNG DGSGKGTHLS LYFVVMRGEF DSLLQWPFRQ 
RVTLMLLDQS GKKNHIVETF KADPNSSSFK RPDGEMNIAS GCPRFVSHST LENSKNTYIK 
DDTLFLKVAV DLTDLEDL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Traf5

Associated with

Other Information

TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor. PubMed ID: 8663299

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. PubMed ID: 8790348

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334