Genular: Defining Cellular Identity and Function

Details for: Tnfsf10

Gene ID: 22035

Symbol: Tnfsf10

Ensembl ID: ENSMUSG00000039304

Description: tumor necrosis factor (ligand) superfamily, member 10

Associated with

Apoptosis
(R-MMU-109581)
Casp8 activity is inhibited
(R-MMU-5218900)
Caspase activation via death receptors in the presence of ligand
(R-MMU-140534)
Caspase activation via extrinsic apoptotic signalling pathway
(R-MMU-5357769)
Death receptor signaling
(R-MMU-73887)
Dimerization of procaspase-8
(R-MMU-69416)
Programmed cell death
(R-MMU-5357801)
Regulated necrosis
(R-MMU-5218859)
Regulation by c-flip
(R-MMU-3371378)
Regulation of necroptotic cell death
(R-MMU-5675482)
Ripk1-mediated regulated necrosis
(R-MMU-5213460)
Signal transduction
(R-MMU-162582)
Trail signaling
(R-MMU-75158)
Apoptotic process
(GO:0006915)
Cytokine activity
(GO:0005125)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Immune response
(GO:0006955)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043280)
Positive regulation of extrinsic apoptotic signaling pathway
(GO:2001238)
Positive regulation of release of cytochrome c from mitochondria
(GO:0090200)
Trail binding
(GO:0045569)
Tumor necrosis factor receptor binding
(GO:0005164)
Tumor necrosis factor receptor superfamily binding
(GO:0032813)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Tumor necrosis factor ligand superfamily member 10

Genular Protein ID: 108030524

Symbol: TNF10_MOUSE

Name: Tumor necrosis factor ligand superfamily member 10

UniProtKB Accession Codes:

P50592

Database IDs:

Citations:

PubMed ID: 8777713

Title: Identification and characterization of a new member of the TNF family that induces apoptosis.

PubMed ID: 8777713

DOI: 10.1016/1074-7613(95)90057-8

Sequence Information:

Length: 291
Mass: 33477
Checksum: 3FEACAB9F0D7D802
Sequence:

MPSSGALKDL SFSQHFRMMV ICIVLLQVLL QAVSVAVTYM YFTNEMKQLQ DNYSKIGLAC 
FSKTDEDFWD STDGEILNRP CLQVKRQLYQ LIEEVTLRTF QDTISTVPEK QLSTPPLPRG 
GRPQKVAAHI TGITRRSNSA LIPISKDGKT LGQKIESWES SRKGHSFLNH VLFRNGELVI 
EQEGLYYIYS QTYFRFQEAE DASKMVSKDK VRTKQLVQYI YKYTSYPDPI VLMKSARNSC 
WSRDAEYGLY SIYQGGLFEL KKNDRIFVSV TNEHLMDLDQ EASFFGAFLI N

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tnfsf10

Associated with

Other Information

Identification and characterization of a new member of the TNF family that induces apoptosis. PubMed ID: 8777713

Database document:

PubMed ID: 8777713