Genular: Defining Cellular Identity and Function

Details for: Trf

Gene ID: 22041

Symbol: Trf

Ensembl ID: ENSMUSG00000032554

Description: transferrin

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Hemostasis
(R-MMU-109582)
Iron uptake and transport
(R-MMU-917937)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Transferrin endocytosis and recycling
(R-MMU-917977)
Transport of small molecules
(R-MMU-382551)
Vesicle-mediated transport
(R-MMU-5653656)
Actin filament organization
(GO:0007015)
Antibacterial humoral response
(GO:0019731)
Apical plasma membrane
(GO:0016324)
Basal part of cell
(GO:0045178)
Basal plasma membrane
(GO:0009925)
Basement membrane
(GO:0005604)
Cell surface
(GO:0009986)
Cell tip
(GO:0051286)
Cellular response to iron ion
(GO:0071281)
Clathrin-coated pit
(GO:0005905)
Cytoplasmic vesicle
(GO:0031410)
Dendrite
(GO:0030425)
Dense body
(GO:0097433)
Early endosome
(GO:0005769)
Endocytic vesicle
(GO:0030139)
Endosome
(GO:0005768)
Erk1 and erk2 cascade
(GO:0070371)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Ferric iron binding
(GO:0008199)
Ferrous iron binding
(GO:0008198)
Hfe-transferrin receptor complex
(GO:1990712)
Intracellular iron ion homeostasis
(GO:0006879)
Iron chaperone activity
(GO:0034986)
Iron ion transport
(GO:0006826)
Late endosome
(GO:0005770)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monoatomic ion transport
(GO:0006811)
Osteoclast differentiation
(GO:0030316)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of bone resorption
(GO:0045780)
Positive regulation of cell motility
(GO:2000147)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of myelination
(GO:0031643)
Positive regulation of oligodendrocyte progenitor proliferation
(GO:0070447)
Positive regulation of phosphorylation
(GO:0042327)
Positive regulation of receptor-mediated endocytosis
(GO:0048260)
Protein binding
(GO:0005515)
Recycling endosome
(GO:0055037)
Regulation of iron ion transport
(GO:0034756)
Response to bacterium
(GO:0009617)
Transferrin receptor binding
(GO:1990459)
Vesicle
(GO:0031982)
Vesicle coat
(GO:0030120)

Other Information

Proteins

Serotransferrin

Genular Protein ID: 160395510

Symbol: TRFE_MOUSE

Name: Serotransferrin

UniProtKB Accession Codes:

Q921I1 O35421 Q3UBW7 Q58E69 Q61803 Q62357 Q62358 Q62359 Q63915 Q64515 Q8VII5 Q922C0

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9621303

Title: Comparative sequence analysis of the mouse and human transferrin promoters: hormonal regulation of the transferrin promoter in Sertoli cells.

PubMed ID: 9621303

DOI: 10.1002/(sici)1098-2795(199807)50:3<273::aid-mrd3>3.0.co;2-g

PubMed ID: 3693348

Title: Transferrin mRNA level in the mouse mammary gland is regulated by pregnancy and extracellular matrix.

PubMed ID: 3693348

DOI: 10.1016/s0021-9258(18)45366-5

PubMed ID: 8248032

Title: Transferrin gene expression in maternal liver, fetal liver and placenta during pregnancy in the mouse.

PubMed ID: 8248032

DOI: 10.1016/s0143-4004(05)80458-8

PubMed ID: 3611056

Title: Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions.

PubMed ID: 3611056

DOI: 10.1016/s0021-9258(18)61088-9

PubMed ID: 2601714

Title: Expression from the transferrin gene promoter in transgenic mice.

PubMed ID: 2601714

DOI: 10.1128/mcb.9.11.5154-5162.1989

PubMed ID: 17330941

Title: Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.

PubMed ID: 17330941

DOI: 10.1021/pr0604559

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 697
Mass: 76724
Checksum: 0996A0C3B64CB1B9
Sequence:

MRLTVGALLA CAALGLCLAV PDKTVKWCAV SEHENTKCIS FRDHMKTVLP PDGPRLACVK 
KTSYPDCIKA ISASEADAMT LDGGWVYDAG LTPNNLKPVA AEFYGSVEHP QTYYYAVAVV 
KKGTDFQLNQ LEGKKSCHTG LGRSAGWVIP IGLLFCKLSE PRSPLEKAVS SFFSGSCVPC 
ADPVAFPKLC QLCPGCGCSS TQPFFGYVGA FKCLKDGGGD VAFVKHTTIF EVLPEKADRD 
QYELLCLDNT RKPVDQYEDC YLARIPSHAV VARKNNGKED LIWEILKVAQ EHFGKGKSKD 
FQLFSSPLGK DLLFKDSAFG LLRVPPRMDY RLYLGHNYVT AIRNQQEGVC PEGSIDNSPV 
KWCALSHLER TKCDEWSIIS EGKIECESAE TTEDCIEKIV NGEADAMTLD GGHAYIAGQC 
GLVPVMAEYY ESSNCAIPSQ QGIFPKGYYA VAVVKASDTS ITWNNLKGKK SCHTGVDRTA 
GWNIPMGMLY NRINHCKFDE FFSQGCAPGY EKNSTLCDLC IGPLKCAPNN KEEYNGYTGA 
FRCLVEKGDV AFVKHQTVLD NTEGKNPAEW AKNLKQEDFE LLCPDGTRKP VKDFASCHLA 
QAPNHVVVSR KEKAARVKAV LTSQETLFGG SDCTGNFCLF KSTTKDLLFR DDTKCFVKLP 
EGTTPEKYLG AEYMQSVGNM RKCSTSRLLE ACTFHKH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Trf

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Comparative sequence analysis of the mouse and human transferrin promoters: hormonal regulation of the transferrin promoter in Sertoli cells. PubMed ID: 9621303

Transferrin mRNA level in the mouse mammary gland is regulated by pregnancy and extracellular matrix. PubMed ID: 3693348

Transferrin gene expression in maternal liver, fetal liver and placenta during pregnancy in the mouse. PubMed ID: 8248032

Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions. PubMed ID: 3611056

Expression from the transferrin gene promoter in transgenic mice. PubMed ID: 2601714

Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. PubMed ID: 17330941

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079