Genular: Defining Cellular Identity and Function

Details for: Try4

Gene ID: 22074

Symbol: Try4

Ensembl ID: ENSMUSG00000054106

Description: trypsin 4

Associated with

Activation of matrix metalloproteinases
(R-MMU-1592389)
Alpha-defensins
(R-MMU-1462054)
Antimicrobial peptides
(R-MMU-6803157)
Collagen degradation
(R-MMU-1442490)
Defensins
(R-MMU-1461973)
Degradation of the extracellular matrix
(R-MMU-1474228)
Extracellular matrix organization
(R-MMU-1474244)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Calcium ion binding
(GO:0005509)
Collagen-containing extracellular matrix
(GO:0062023)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hydrolase activity
(GO:0016787)
Metal ion binding
(GO:0046872)
Peptidase activity
(GO:0008233)
Proteolysis
(GO:0006508)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)

Other Information

Proteins

TRY4_MOUSE

Genular Protein ID: 873472242

Symbol: TRY4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9R0T7

Database IDs:

Citations:

PubMed ID: 10506205

Title: A homologue of pancreatic trypsin is localized in the acrosome of mammalian sperm and is released during acrosome reaction.

PubMed ID: 10506205

DOI: 10.1074/jbc.274.41.29426

PubMed ID: 11160223

Title: Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement.

PubMed ID: 11160223

DOI: 10.4049/jimmunol.166.3.1771

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23814066

Title: Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

PubMed ID: 23814066

DOI: 10.1074/jbc.m113.478800

Sequence Information:

Length: 246
Mass: 26274
Checksum: B6A9F4C99079633F
Sequence:

MRALLFLALV GAAVAFPVDD DDKIVGGYTC RENSVPYQVS LNSGYHFCGG SLINDQWVVS 
AAHCYKSRIQ VRLGEHNINV LEGNEQFVNS AKIIKHPNFN SRTLNNDIML IKLASPVTLN 
ARVATVALPS SCAPAGTQCL ISGWGNTLSF GVNNPDLLQC LDAPLLPQAD CEASYPGKIT 
NNMICVGFLE GGKDSCQGDS GGPVVCNGQL QGIVSWGYGC ALKDNPGVYT KVCNYVDWIQ 
NTIAAN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Try4

Associated with

Other Information

A homologue of pancreatic trypsin is localized in the acrosome of mammalian sperm and is released during acrosome reaction. PubMed ID: 10506205

Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement. PubMed ID: 11160223

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334