Details for: Tssk2

Gene ID: 22115

Symbol: Tssk2

Ensembl ID: ENSMUSG00000045521

Description: testis-specific serine kinase 2

Associated with

Other Information

Genular Protein ID: 3388969549

Symbol: TSSK2_MOUSE

Name: Testis-specific serine/threonine-protein kinase 2

UniProtKB Accession Codes:

O54863 Q6P8M9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 13 ChiTaRS 1 DNASU 1 EC 2 EMBL 3 Ensembl 1 GO 16 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 Rhea 6 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9412477

Title: A novel family of serine/threonine kinases participating in spermiogenesis.

PubMed ID: 9412477

DOI: 10.1083/jcb.139.7.1851

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9651519

Title: Immunohistochemical analysis of the expression of two serine-threonine kinases in the maturing mouse testis.

PubMed ID: 9651519

DOI: 10.1016/s0925-4773(98)00060-4

PubMed ID: 10781952

Title: A novel member of the testis specific serine kinase family, tssk-3, expressed in the Leydig cells of sexually mature mice.

PubMed ID: 10781952

DOI: 10.1016/s0925-4773(00)00255-0

PubMed ID: 18367677

Title: Phosphorylation of mouse sperm axoneme central apparatus protein SPAG16L by a testis-specific kinase, TSSK2.

PubMed ID: 18367677

DOI: 10.1095/biolreprod.107.066308

PubMed ID: 18495105

Title: TSKS concentrates in spermatid centrioles during flagellogenesis.

PubMed ID: 18495105

DOI: 10.1016/j.ydbio.2008.03.043

PubMed ID: 18533145

Title: Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency.

PubMed ID: 18533145

DOI: 10.1016/j.ydbio.2008.03.047

PubMed ID: 20053632

Title: Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases.

PubMed ID: 20053632

DOI: 10.1242/jcs.059949

PubMed ID: 20729278

Title: Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis.

PubMed ID: 20729278

DOI: 10.1093/molehr/gaq071

PubMed ID: 23599433

Title: Heat shock protein 90 functions to stabilize and activate the testis-specific serine/threonine kinases, a family of kinases essential for male fertility.

PubMed ID: 23599433

DOI: 10.1074/jbc.m112.400978

Sequence Information:

  • Length: 358
  • Mass: 41022
  • Checksum: 551F2AAEB0BBAF31
  • Sequence:
    • MDDAAVLRKK GYIVGINLGK GSYAKVKSAY SERLKFNVAV KIIDRKKTPT DFVERFLPRE 
MDILATVNHR SIIKTYEIFE TSDGRIYIVM ELGVQGDLLE FIKCRGALHE DVARKMFRQL 
SSAVKYCHDL DVVHRDLKCE NLLLDKDFNI KLSDFGFSKR CLRDGSGRIV LSKTFCGSAA 
YAAPEVLQGI PYQPKVYDIW SLGVILYIMV CGSMPYDDSD IKKMLRIQKE HRVDFPRSKN 
LTGECKDLIY RILQPDVNRR LHIDEILSHS WLQPPKPKAM SSASFKREGE GKYRADCKLD 
TRPGSRPEHR PDHKLATKPQ QRMLVTPENE DRMEDRLAET SRAKDHHISG AEVEKAST

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.