Genular: Defining Cellular Identity and Function

Details for: Txn1

Gene ID: 22166

Symbol: Txn1

Ensembl ID: ENSMUSG00000028367

Description: thioredoxin 1

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Cellular senescence
(R-MMU-2559583)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Immune system
(R-MMU-168256)
Inflammasomes
(R-MMU-622312)
Innate immune system
(R-MMU-168249)
Interconversion of nucleotide di- and triphosphates
(R-MMU-499943)
Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
Metabolism of proteins
(R-MMU-392499)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-MMU-168643)
Oxidative stress induced senescence
(R-MMU-2559580)
Protein repair
(R-MMU-5676934)
Rna polymerase ii transcription
(R-MMU-73857)
The nlrp3 inflammasome
(R-MMU-844456)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Axon
(GO:0030424)
Cell redox homeostasis
(GO:0045454)
Cellular detoxification of hydrogen peroxide
(GO:0061692)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Enzyme binding
(GO:0019899)
Extracellular region
(GO:0005576)
Mitochondrion
(GO:0005739)
Negative regulation of protein export from nucleus
(GO:0046826)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuronal cell body
(GO:0043025)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna binding
(GO:0043388)
Positive regulation of peptidyl-cysteine s-nitrosylation
(GO:2000170)
Positive regulation of peptidyl-serine phosphorylation
(GO:0033138)
Protein-disulfide reductase (nad(p)) activity
(GO:0047134)
Protein-disulfide reductase activity
(GO:0015035)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Response to nitric oxide
(GO:0071731)
Response to radiation
(GO:0009314)

Other Information

Proteins

Thioredoxin

Genular Protein ID: 1469185605

Symbol: THIO_MOUSE

Name: Thioredoxin

UniProtKB Accession Codes:

P10639 Q52KC4 Q9D8R0

Database IDs:

Citations:

PubMed ID: 2785919

Title: ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction.

PubMed ID: 2785919

DOI: 10.1002/j.1460-2075.1989.tb03436.x

PubMed ID: 8187776

Title:

PubMed ID: 8187776

DOI: 10.1002/j.1460-2075.1994.tb06502.x

PubMed ID: 7835695

Title: Structure of the mouse thioredoxin-encoding gene and its processed pseudogene.

PubMed ID: 7835695

DOI: 10.1016/0378-1119(94)00707-y

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10843682

Title: Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function.

PubMed ID: 10843682

DOI: 10.4049/jimmunol.164.12.6287

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 105
Mass: 11675
Checksum: 3A2B925935F952DA
Sequence:

MVKLIESKEA FQEALAAAGD KLVVVDFSAT WCGPCKMIKP FFHSLCDKYS NVVFLEVDVD 
DCQDVAADCE VKCMPTFQFY KKGQKVGEFS GANKEKLEAS ITEYA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Txn1

Associated with

Other Information

ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction. PubMed ID: 2785919

PubMed ID: 8187776

Structure of the mouse thioredoxin-encoding gene and its processed pseudogene. PubMed ID: 7835695

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. PubMed ID: 10843682

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337