Details for: Tyrobp
Associated with
Other Information
Genular Protein ID: 1281271897
Symbol: TYOBP_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9490415
Title: Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells.
PubMed ID: 9490415
DOI: 10.1038/35642
PubMed ID: 9852069
Title: Gene structure, expression pattern, and biological activity of mouse killer cell activating receptor-associated protein (KARAP)/DAP-12.
PubMed ID: 9852069
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9647200
Title: Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors.
PubMed ID: 9647200
PubMed ID: 10449773
Title: Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells.
PubMed ID: 10449773
PubMed ID: 11754004
Title: Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17.
PubMed ID: 11754004
DOI: 10.1002/1521-4141(200201)32:1<59::aid-immu59>3.0.co;2-u
PubMed ID: 12426565
Title: Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D.
PubMed ID: 12426565
DOI: 10.1038/ni858
PubMed ID: 12426564
Title: NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation.
PubMed ID: 12426564
DOI: 10.1038/ni857
PubMed ID: 12893283
Title: Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.
PubMed ID: 12893283
PubMed ID: 12569157
Title: Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice.
PubMed ID: 12569157
DOI: 10.1172/jci16923
PubMed ID: 12874256
Title: Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation.
PubMed ID: 12874256
DOI: 10.1084/jem.20021825
PubMed ID: 15471863
Title: CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells.
PubMed ID: 15471863
PubMed ID: 14969392
Title: The signaling adapter protein DAP12 regulates multinucleation during osteoclast development.
PubMed ID: 14969392
DOI: 10.1359/jbmr.0301234
PubMed ID: 15294961
Title: A Structural basis for the association of DAP12 with mouse, but not human, NKG2D.
PubMed ID: 15294961
PubMed ID: 17086186
Title: Integrin signaling in neutrophils and macrophages uses adapters containing immunoreceptor tyrosine-based activation motifs.
PubMed ID: 17086186
DOI: 10.1038/ni1407
PubMed ID: 15728241
Title: Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.
PubMed ID: 15728241
DOI: 10.1084/jem.20041611
PubMed ID: 17202337
Title: Dual assemblies of an activating immune receptor, MAIR-II, with ITAM-bearing adapters DAP12 and FcRgamma chain on peritoneal macrophages.
PubMed ID: 17202337
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 17928527
Title: Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells.
PubMed ID: 17928527
PubMed ID: 18685038
Title: Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor.
PubMed ID: 18685038
PubMed ID: 18691974
Title: DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk.
PubMed ID: 18691974
PubMed ID: 18957693
Title: Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.
PubMed ID: 18957693
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21727189
Title: The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.
PubMed ID: 21727189
DOI: 10.1084/jem.20101623
PubMed ID: 21257958
Title: DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability.
PubMed ID: 21257958
PubMed ID: 24078628
Title: Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and gamma-secretase-dependent intramembranous cleavage.
PubMed ID: 24078628
PubMed ID: 25690660
Title: A DAP12-dependent signal promotes pro-inflammatory polarization in microglia following nerve injury and exacerbates degeneration of injured neurons.
PubMed ID: 25690660
DOI: 10.1002/glia.22802
PubMed ID: 29518356
Title: TREM2 Is a Receptor for beta-Amyloid that Mediates Microglial Function.
PubMed ID: 29518356
Sequence Information:
- Length: 114
- Mass: 12367
- Checksum: 6A530D52E51FED8F
- Sequence:
MGALEPSWCL LFLPVLLTVG GLSPVQAQSD TFPRCDCSSV SPGVLAGIVL GDLVLTLLIA LAVYSLGRLV SRGQGTAEGT RKQHIAETES PYQELQGQRP EVYSDLNTQR QYYR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.