Details for: Tyrp1
Associated with
Other Information
Genular Protein ID: 1254253983
Symbol: TYRP1_MOUSE
Name: 5,6-dihydroxyindole-2-carboxylic acid oxidase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3008090
Title: Cloning and expression of cDNA encoding mouse tyrosinase.
PubMed ID: 3008090
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3132713
Title: A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse.
PubMed ID: 3132713
PubMed ID: 1693779
Title: Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity.
PubMed ID: 1693779
PubMed ID: 1537333
Title: A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase.
PubMed ID: 1537333
PubMed ID: 8270621
Title: The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts.
PubMed ID: 8270621
PubMed ID: 7813420
Title: Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis.
PubMed ID: 7813420
PubMed ID: 17182842
Title: BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.
PubMed ID: 17182842
PubMed ID: 18650808
Title: Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.
PubMed ID: 18650808
DOI: 10.1038/nature07163
PubMed ID: 26620560
Title: RUTBC1 functions as a GTPase-activating protein for Rab32/38 and regulates melanogenic enzyme trafficking in melanocytes.
PubMed ID: 26620560
PubMed ID: 35469906
Title: Ablation of H+/glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis.
PubMed ID: 35469906
PubMed ID: 2245916
Title: The molecular basis of brown, an old mouse mutation, and of an induced revertant to wild type.
PubMed ID: 2245916
Sequence Information:
- Length: 537
- Mass: 60761
- Checksum: 86570998AA9EB0BC
- Sequence:
MKSYNVLPLA YISLFLMLFY QVWAQFPREC ANIEALRRGV CCPDLLPSSG PGTDPCGSSS GRGRCVAVIA DSRPHSRHYP HDGKDDREAW PLRFFNRTCQ CNDNFSGHNC GTCRPGWRGA ACNQKILTVR RNLLDLSPEE KSHFVRALDM AKRTTHPQFV IATRRLEDIL GPDGNTPQFE NISVYNYFVW THYYSVKKTF LGTGQESFGD VDFSHEGPAF LTWHRYHLLQ LERDMQEMLQ EPSFSLPYWN FATGKNVCDV CTDDLMGSRS NFDSTLISPN SVFSQWRVVC ESLEEYDTLG TLCNSTEGGP IRRNPAGNVG RPAVQRLPEP QDVTQCLEVR VFDTPPFYSN STDSFRNTVE GYSAPTGKYD PAVRSLHNLA HLFLNGTGGQ THLSPNDPIF VLLHTFTDAV FDEWLRRYNA DISTFPLENA PIGHNRQYNM VPFWPPVTNT EMFVTAPDNL GYAYEVQWPG QEFTVSEIIT IAVVAALLLV AAIFGVASCL IRSRSTKNEA NQPLLTDHYQ RYAEDYEELP NPNHSMV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.