Genular: Defining Cellular Identity and Function

Details for: Ube2e1

Gene ID: 22194

Symbol: Ube2e1

Ensembl ID: ENSMUSG00000021774

Description: ubiquitin-conjugating enzyme E2E 1

Associated with

Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
(R-MMU-176814)
Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Antiviral mechanism by ifn-stimulated genes
(R-MMU-1169410)
Apc-cdc20 mediated degradation of nek2a
(R-MMU-179409)
Apc/c-mediated degradation of cell cycle proteins
(R-MMU-174143)
Apc/c:cdc20 mediated degradation of cyclin b
(R-MMU-174048)
Apc/c:cdc20 mediated degradation of mitotic proteins
(R-MMU-176409)
Apc/c:cdc20 mediated degradation of securin
(R-MMU-174154)
Apc/c:cdh1 mediated degradation of cdc20 and other apc/c:cdh1 targeted proteins in late mitosis/early g1
(R-MMU-174178)
Apc:cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
(R-MMU-179419)
Assembly of the pre-replicative complex
(R-MMU-68867)
Autodegradation of cdh1 by cdh1:apc/c
(R-MMU-174084)
Cdc20:phospho-apc/c mediated degradation of cyclin a
(R-MMU-174184)
Cdk-mediated phosphorylation and removal of cdc6
(R-MMU-69017)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Conversion from apc/c:cdc20 to apc/c:cdh1 in late anaphase
(R-MMU-176407)
Cytokine signaling in immune system
(R-MMU-1280215)
Dna replication
(R-MMU-69306)
Dna replication pre-initiation
(R-MMU-69002)
E3 ubiquitin ligases ubiquitinate target proteins
(R-MMU-8866654)
Immune system
(R-MMU-168256)
Inactivation of apc/c via direct inhibition of the apc/c complex
(R-MMU-141430)
Inhibition of the proteolytic activity of apc/c required for the onset of anaphase by mitotic spindle checkpoint components
(R-MMU-141405)
Interferon signaling
(R-MMU-913531)
Isg15 antiviral mechanism
(R-MMU-1169408)
Metabolism of proteins
(R-MMU-392499)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Phosphorylation of the apc/c
(R-MMU-176412)
Post-translational protein modification
(R-MMU-597592)
Regulation of apc/c activators between g1/s and early anaphase
(R-MMU-176408)
Regulation of mitotic cell cycle
(R-MMU-453276)
Senescence-associated secretory phenotype (sasp)
(R-MMU-2559582)
Separation of sister chromatids
(R-MMU-2467813)
S phase
(R-MMU-69242)
Switching of origins to a post-replicative state
(R-MMU-69052)
Synthesis of active ubiquitin: roles of e1 and e2 enzymes
(R-MMU-8866652)
Synthesis of dna
(R-MMU-69239)
Atp binding
(GO:0005524)
Isg15 transferase activity
(GO:0042296)
Isg15-protein conjugation
(GO:0032020)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein k48-linked ubiquitination
(GO:0070936)
Protein polyubiquitination
(GO:0000209)
Protein ubiquitination
(GO:0016567)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin conjugating enzyme activity
(GO:0061631)
Ubiquitin ligase complex
(GO:0000151)

Other Information

Proteins

Ubiquitin-conjugating enzyme E2 E1

Genular Protein ID: 1931312382

Symbol: UB2E1_MOUSE

Name: Ubiquitin-conjugating enzyme E2 E1

UniProtKB Accession Codes:

P52482

Database IDs:

Citations:

PubMed ID: 8576256

Title: Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions.

PubMed ID: 8576256

DOI: 10.1074/jbc.271.5.2789

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 193
Mass: 21333
Checksum: B535B3095EF6C445
Sequence:

MSDDDSRAST SSSSSSSSNQ QTEKEGSTPK KKESKVSMSK NSKLLSTSAK RIQKELADIT 
LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY 
HCNINSQGVI CLDILKDNWS PALTISKVLL SICSLLTDCN PADPLVGSIA TQYMTNRAEH 
DRMARQWTKR YAT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.