Genular: Defining Cellular Identity and Function

Details for: Ube2l3

Gene ID: 22195

Symbol: Ube2l3

Ensembl ID: ENSMUSG00000038965

Description: ubiquitin-conjugating enzyme E2L 3

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Death receptor signaling
(R-MMU-73887)
E3 ubiquitin ligases ubiquitinate target proteins
(R-MMU-8866654)
Immune system
(R-MMU-168256)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Programmed cell death
(R-MMU-5357801)
Regulated necrosis
(R-MMU-5218859)
Regulation of necroptotic cell death
(R-MMU-5675482)
Regulation of tnfr1 signaling
(R-MMU-5357905)
Ripk1-mediated regulated necrosis
(R-MMU-5213460)
Signal transduction
(R-MMU-162582)
Synthesis of active ubiquitin: roles of e1 and e2 enzymes
(R-MMU-8866652)
Tnf signaling
(R-MMU-75893)
Atp binding
(GO:0005524)
Cell cycle phase transition
(GO:0044770)
Cell population proliferation
(GO:0008283)
Cellular response to glucocorticoid stimulus
(GO:0071385)
Cellular response to steroid hormone stimulus
(GO:0071383)
Cytoplasm
(GO:0005737)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Positive regulation of protein ubiquitination
(GO:0031398)
Positive regulation of ubiquitin-protein transferase activity
(GO:0051443)
Protein binding
(GO:0005515)
Protein k11-linked ubiquitination
(GO:0070979)
Protein polyubiquitination
(GO:0000209)
Protein ubiquitination
(GO:0016567)
Regulation of dna-templated transcription
(GO:0006355)
Transcription coactivator activity
(GO:0003713)
Transferase activity
(GO:0016740)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin-protein transferase activator activity
(GO:0097027)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin conjugating enzyme activity
(GO:0061631)
Ubiquitin ligase complex
(GO:0000151)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Ubiquitin-conjugating enzyme E2 L3

Genular Protein ID: 1440822429

Symbol: UB2L3_MOUSE

Name: Ubiquitin-conjugating enzyme E2 L3

UniProtKB Accession Codes:

P68037 P51966 P70653 Q9HAV1

Database IDs:

Citations:

PubMed ID: 8901595

Title: Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality.

PubMed ID: 8901595

DOI: 10.1073/pnas.93.22.12412

PubMed ID: 8563171

Title: A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3.

PubMed ID: 8563171

DOI: 10.1007/bf00354295

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25632008

Title: Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7.

PubMed ID: 25632008

DOI: 10.4049/jimmunol.1402742

Sequence Information:

Length: 154
Mass: 17862
Checksum: F5A30243BE3C9985
Sequence:

MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE 
YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP 
LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ube2l3

Associated with

Other Information

Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality. PubMed ID: 8901595

A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3. PubMed ID: 8563171

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072