Genular: Defining Cellular Identity and Function

Details for: Ube2b

Gene ID: 22210

Symbol: Ube2b

Ensembl ID: ENSMUSG00000020390

Description: ubiquitin-conjugating enzyme E2B

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Dna damage bypass
(R-MMU-73893)
E3 ubiquitin ligases ubiquitinate target proteins
(R-MMU-8866654)
Immune system
(R-MMU-168256)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Recognition of dna damage by pcna-containing replication complex
(R-MMU-110314)
Synthesis of active ubiquitin: roles of e1 and e2 enzymes
(R-MMU-8866652)
Apoptotic process
(GO:0006915)
Atp binding
(GO:0005524)
Chiasma assembly
(GO:0051026)
Chromatin
(GO:0000785)
Chromatin organization
(GO:0006325)
Cytoplasm
(GO:0005737)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Ectopic germ cell programmed cell death
(GO:0035234)
Hulc complex
(GO:0033503)
In utero embryonic development
(GO:0001701)
Leptotene
(GO:0000237)
Meiotic telomere clustering
(GO:0045141)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of camp-mediated signaling
(GO:0043951)
Negative regulation of developmental process
(GO:0051093)
Negative regulation of post-translational protein modification
(GO:1901874)
Negative regulation of reproductive process
(GO:2000242)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of reciprocal meiotic recombination
(GO:0010845)
Postreplication repair
(GO:0006301)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein autoubiquitination
(GO:0051865)
Protein binding
(GO:0005515)
Protein k11-linked ubiquitination
(GO:0070979)
Protein k48-linked ubiquitination
(GO:0070936)
Protein k63-linked ubiquitination
(GO:0070534)
Protein polyubiquitination
(GO:0000209)
Protein stabilization
(GO:0050821)
Protein ubiquitination
(GO:0016567)
Replication fork
(GO:0005657)
Response to uv
(GO:0009411)
Response to xenobiotic stimulus
(GO:0009410)
Spermatogenesis
(GO:0007283)
Sperm axoneme assembly
(GO:0007288)
Synaptonemal complex organization
(GO:0070193)
Transferase activity
(GO:0016740)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin conjugating enzyme activity
(GO:0061631)
Ubiquitin protein ligase binding
(GO:0031625)
Xy body
(GO:0001741)

Other Information

Proteins

E2 ubiquitin-conjugating enzyme B

Genular Protein ID: 4014750316

Symbol: UBE2B_MOUSE

Name: E2 ubiquitin-conjugating enzyme B

UniProtKB Accession Codes:

P63147 P23567 Q3UGS2 Q9D0J6

Database IDs:

Citations:

PubMed ID: 8797826

Title: Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.

PubMed ID: 8797826

DOI: 10.1016/s0092-8674(00)80154-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 14585983

Title: Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.

PubMed ID: 14585983

DOI: 10.1128/mcb.23.22.8255-8271.2003

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 152
Mass: 17312
Checksum: CFDEEEE7E06840BE
Sequence:

MSTPARRRLM RDFKRLQEDP PVGVSGAPSE NNIMQWNAVI FGPEGTPFED GTFKLVIEFS 
EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 
PANSQAAQLY QENKREYEKR VSAIVEQSWN DS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ube2b

Associated with

Other Information

Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. PubMed ID: 8797826

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. PubMed ID: 14585983

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 8797826

PubMed ID: 16141072

PubMed ID: 14585983

PubMed ID: 21183079