Details for: Ugcg

Gene ID: 22234

Symbol: Ugcg

Ensembl ID: ENSMUSG00000028381

Description: UDP-glucose ceramide glucosyltransferase

Associated with

Other Information

Genular Protein ID: 2538363565

Symbol: CEGT_MOUSE

Name: GLCT-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9918791

Title: Molecular cloning and characterization of the mouse ceramide glucosyltransferase gene.

PubMed ID: 9918791

DOI: 10.1006/bbrc.1998.9855

PubMed ID: 9623774

Title: Molecular cloning and expression of mouse ceramide glucosyltransferase.

PubMed ID: 9623774

DOI: 10.1080/15216549800202282

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10430909

Title: A vital role for glycosphingolipid synthesis during development and differentiation.

PubMed ID: 10430909

DOI: 10.1073/pnas.96.16.9142

PubMed ID: 12417405

Title: Early developmental expression of the gene encoding glucosylceramide synthase, the enzyme controlling the first committed step of glycosphingolipid synthesis.

PubMed ID: 12417405

DOI: 10.1016/s0304-4165(02)00389-6

PubMed ID: 16109770

Title: Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth.

PubMed ID: 16109770

DOI: 10.1073/pnas.0500893102

PubMed ID: 17145749

Title: Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis.

PubMed ID: 17145749

DOI: 10.1074/jbc.m610304200

PubMed ID: 20544855

Title: Glycosphingolipid synthesis in cerebellar Purkinje neurons: roles in myelin formation and axonal homeostasis.

PubMed ID: 20544855

DOI: 10.1002/glia.20999

PubMed ID: 20432257

Title: Hepatic glycosphingolipid deficiency and liver function in mice.

PubMed ID: 20432257

DOI: 10.1002/hep.23545

PubMed ID: 22851168

Title: Glycosphingolipids are essential for intestinal endocytic function.

PubMed ID: 22851168

DOI: 10.1074/jbc.m112.371005

PubMed ID: 23748427

Title: Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing.

PubMed ID: 23748427

DOI: 10.1093/hmg/ddt264

PubMed ID: 23554574

Title: Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.

PubMed ID: 23554574

DOI: 10.1371/journal.pbio.1001506

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 28373486

Title: Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals.

PubMed ID: 28373486

DOI: 10.1194/jlr.d076190

PubMed ID: 33361282

Title: Human glucocerebrosidase mediates formation of xylosyl-cholesterol by beta-xylosidase and transxylosidase reactions.

PubMed ID: 33361282

DOI: 10.1194/jlr.ra120001043

Sequence Information:

  • Length: 394
  • Mass: 44839
  • Checksum: 8B18D09437CACE0E
  • Sequence:
  • MALLDLAQEG MALFGFVLFV VLWLMHFMSI IYTRLHLNKK ATDKQPYSKL PGVSLLKPLK 
    GVDPNLINNL ETFFELDYPK YEVLLCVQDH DDPAIDVCKK LLGKYPNVDA RLFIGGKKVG 
    INPKINNLMP AYEVAKYDLI WICDSGIRVI PDTLTDMVNQ MTEKVGLVHG LPYVADRQGF 
    AATLEQVYFG TSHPRSYISA NVTGFKCVTG MSCLMRKDVL DQAGGLIAFA QYIAEDYFMA 
    KAIADRGWRF SMSTQVAMQN SGSYSISQFQ SRMIRWTKLR INMLPATIIC EPISECFVAS 
    LIIGWAAHHV FRWDIMVFFM CHCLAWFIFD YIQLRGVQGG TLCFSKLDYA VAWFIRESMT 
    IYIFLSALWD PTISWRTGRY RLRCGGTAEE ILDV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.