Genular: Defining Cellular Identity and Function

Details for: Ugt1a2

Gene ID: 22236

Symbol: Ugt1a2

Ensembl ID: ENSMUSG00000090171

Description: UDP glucuronosyltransferase 1 family, polypeptide A2

Associated with

Aspirin adme
(R-MMU-9749641)
Atorvastatin adme
(R-MMU-9754706)
Biological oxidations
(R-MMU-211859)
Drug adme
(R-MMU-9748784)
Glucuronidation
(R-MMU-156588)
Heme degradation
(R-MMU-189483)
Metabolism
(R-MMU-1430728)
Metabolism of porphyrins
(R-MMU-189445)
Phase ii - conjugation of compounds
(R-MMU-156580)
Prednisone adme
(R-MMU-9757110)
Cellular glucuronidation
(GO:0052695)
Endoplasmic reticulum
(GO:0005783)
Enzyme binding
(GO:0019899)
Glucuronosyltransferase activity
(GO:0015020)
Glycosyltransferase activity
(GO:0016757)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Retinoic acid binding
(GO:0001972)
Transferase activity
(GO:0016740)
Udp-glycosyltransferase activity
(GO:0008194)

Other Information

Proteins

UDP-glucuronosyltransferase 1-2

Genular Protein ID: 3637332942

Symbol: UD12_MOUSE

Name: UDP-glucuronosyltransferase 1-2

UniProtKB Accession Codes:

P70691 Q545X2 Q6XL49

Database IDs:

Citations:

PubMed ID: 7677729

Title: Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations.

PubMed ID: 7677729

DOI: 10.1007/bf00557949

PubMed ID: 14672974

Title: Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

PubMed ID: 14672974

DOI: 10.1101/gr.1225204

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 533
Mass: 60285
Checksum: FB458439525550FA
Sequence:

MDTGLCVPLR GISGLLLLLC ALPWAEGAKV LVLPMEGSQW LSMRDVVREL HARGHQTVVL 
ASEVTVHIKG EDFFTLKTYA FPYTKEEYQQ EILSDIEKTF KTQHFVKAFF ETTASIRNFF 
DLYSNSCIAL LHNKMLIQQL NSSFFDVILT DPIFPCGAVL AKYLQIPAVF ILRSLSCGIE 
YEATQCPNPS SYIPNLLTRL SDHMDFLQRV QNMLYYLVLK YICRLSITPY ESLASELLQR 
EVSLVEVLSH ASVWLFRGDF VLDYPRPIMP NMVFIGGINC VTKKPLSQEF EAYVNASGEH 
GIVVFSLGSM VSEIPEKKAM EIAEALGRIP QTVLWRYTGT RPSNLAKNTI LVKWLPQNDL 
LGHPKTRAFI THSGSHGIYE GICNGVPMVM MPLFGDQMDN AKRMETRGAG VTLNVLEMTA 
DDLENALKTV INNKSYKENI MRLSSLHKDR PIEPLDLAVF WVEYVMRHKG APHLRPAAHD 
LTWYQYHSLD VIGFLLAIVL TVVFIVFKCC AYGCRKCFGG KGRVKKSHKS KTH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ugt1a2

Associated with

Other Information

Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations. PubMed ID: 7677729

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. PubMed ID: 14672974

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072