Details for: Slc45a2

Gene ID: 22293

Symbol: Slc45a2

Ensembl ID: ENSMUSG00000022243

Description: solute carrier family 45, member 2

Associated with

Other Information

Genular Protein ID: 1929509048

Symbol: S45A2_MOUSE

Name: Membrane-associated transporter protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11479596

Title: Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka.

PubMed ID: 11479596

DOI: 10.1038/ng584

PubMed ID: 11574907

Title: Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4.

PubMed ID: 11574907

DOI: 10.1086/324340

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 25164149

Title: Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae.

PubMed ID: 25164149

DOI: 10.1042/bj20140572

PubMed ID: 32966160

Title: SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation.

PubMed ID: 32966160

DOI: 10.1091/mbc.e20-03-0200

PubMed ID: 35469906

Title: Ablation of H+/glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis.

PubMed ID: 35469906

DOI: 10.1016/j.jid.2022.04.008

Sequence Information:

  • Length: 530
  • Mass: 57961
  • Checksum: F4EDEAD07916D9FC
  • Sequence:
  • MSGSNGPTDT HTYQSLAEDC PFGSVEQPKR STGRLVMHSM AMFGREFCYA VEAAYVTPVL 
    LSVGLPKSLY SMVWLLSPIL GFLLQPVVGS ASDHCRARWG RRRPYILTLA IMMLLGMALY 
    LNGDAVVSAL VANPRQKLIW AISITMVGVV LFDFSADFID GPIKAYLFDV CSHQDKEKGL 
    HYHALFTGFG GALGYILGAI DWVHLDLGRL LGTEFQVMFF FSALVLILCF ITHLCSIPEA 
    PLRDAATDPP SQQDPQGSSL SASGMHEYGS IEKVKNGGAD TEQPVQEWKN KKPSGQSQRT 
    MSMKSLLRAL VNMPSHYRCL CVSHLIGWTA FLSNMLFFTD FMGQIVYHGD PYGAHNSTEF 
    LIYERGVEVG CWGLCINSVF SSVYSYFQKA MVSYIGLKGL YFMGYLLFGL GTGFIGLFPN 
    VYSTLVLCSM FGVMSSTLYT VPFNLIAEYH REEEKEKGQE APGGPDNQGR GKGVDCAALT 
    CMVQLAQILV GGGLGFLVNM AGSVVVVVIT ASAVSLIGCC FVALFVRYVD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.