Details for: ALDH9A1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 208.0424
Cell Significance Index: -32.3600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 121.2332
Cell Significance Index: -30.7500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 94.9271
Cell Significance Index: -39.1100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 79.6615
Cell Significance Index: -37.6100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 79.5063
Cell Significance Index: -32.3000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 70.4530
Cell Significance Index: -36.2400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 56.2128
Cell Significance Index: -37.7200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 29.4414
Cell Significance Index: -36.3000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.7900
Cell Significance Index: -28.9100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.3030
Cell Significance Index: -36.7100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.2995
Cell Significance Index: -22.4200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 4.0590
Cell Significance Index: 280.7000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.8722
Cell Significance Index: 467.1400 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 2.8631
Cell Significance Index: 30.4200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.6366
Cell Significance Index: 122.9300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.4717
Cell Significance Index: 148.3900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 2.1861
Cell Significance Index: 254.7700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.9595
Cell Significance Index: 52.5100 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.4240
Cell Significance Index: 8.8100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.2897
Cell Significance Index: 91.2100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.0809
Cell Significance Index: 148.4400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.9831
Cell Significance Index: 25.8500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.8300
Cell Significance Index: 10.6300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8180
Cell Significance Index: 11.1600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.7101
Cell Significance Index: 387.8200 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.6997
Cell Significance Index: 90.3900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.6849
Cell Significance Index: 302.8200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.6075
Cell Significance Index: 28.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5690
Cell Significance Index: 69.9700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.5242
Cell Significance Index: 67.2000 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.5173
Cell Significance Index: 4.1300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5132
Cell Significance Index: 97.6700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4907
Cell Significance Index: 88.4500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.4884
Cell Significance Index: 36.4000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.4464
Cell Significance Index: 15.5100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.4341
Cell Significance Index: 124.8900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4132
Cell Significance Index: 82.0100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.3685
Cell Significance Index: 10.0300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3662
Cell Significance Index: 39.8400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3293
Cell Significance Index: 17.1100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2580
Cell Significance Index: 7.2100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2489
Cell Significance Index: 7.1700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2238
Cell Significance Index: 38.2200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1830
Cell Significance Index: 36.7100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1550
Cell Significance Index: 55.6000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1471
Cell Significance Index: 17.3500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1306
Cell Significance Index: 8.4300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1286
Cell Significance Index: 12.7200 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.1069
Cell Significance Index: 1.5000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0379
Cell Significance Index: 27.7800 - Cell Name: peg cell (CL4033014)
Fold Change: 0.0294
Cell Significance Index: 0.6800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0258
Cell Significance Index: 0.5400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0191
Cell Significance Index: 13.2400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0128
Cell Significance Index: 0.2200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0097
Cell Significance Index: 8.7500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0061
Cell Significance Index: 4.6400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0041
Cell Significance Index: -3.0400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0043
Cell Significance Index: -8.0800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0085
Cell Significance Index: -0.4400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0141
Cell Significance Index: -26.0600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0183
Cell Significance Index: -11.4200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0206
Cell Significance Index: -31.7400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0212
Cell Significance Index: -1.3400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0218
Cell Significance Index: -2.2300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0270
Cell Significance Index: -17.1700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0282
Cell Significance Index: -38.2900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0382
Cell Significance Index: -21.5400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0555
Cell Significance Index: -25.1800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0662
Cell Significance Index: -13.9500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0685
Cell Significance Index: -9.9600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0735
Cell Significance Index: -8.3900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0895
Cell Significance Index: -2.3900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0968
Cell Significance Index: -11.0900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1379
Cell Significance Index: -4.0500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1509
Cell Significance Index: -6.8400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1757
Cell Significance Index: -4.7000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1864
Cell Significance Index: -6.5500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1882
Cell Significance Index: -11.5700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1929
Cell Significance Index: -4.1800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2100
Cell Significance Index: -16.6300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2235
Cell Significance Index: -4.7600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2666
Cell Significance Index: -8.5400 - Cell Name: theca cell (CL0000503)
Fold Change: -0.2860
Cell Significance Index: -1.6800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2937
Cell Significance Index: -8.4200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2974
Cell Significance Index: -22.8200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3077
Cell Significance Index: -7.8600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3494
Cell Significance Index: -36.3800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3557
Cell Significance Index: -19.9600 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.3926
Cell Significance Index: -4.4600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4147
Cell Significance Index: -10.6600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4262
Cell Significance Index: -28.6600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.4510
Cell Significance Index: -7.9700 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.4605
Cell Significance Index: -6.9000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4686
Cell Significance Index: -4.3200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.4817
Cell Significance Index: -25.0900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.5562
Cell Significance Index: -28.1100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5614
Cell Significance Index: -34.4200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.6384
Cell Significance Index: -12.4600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.6656
Cell Significance Index: -29.4400 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.6967
Cell Significance Index: -7.2100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3421475646
Symbol: AL9A1_HUMAN
Name: 4-trimethylaminobutyraldehyde dehydrogenase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8786138
Title: Human gamma-aminobutyraldehyde dehydrogenase (ALDH9): cDNA sequence, genomic organization, polymorphism, chromosomal localization, and tissue expression.
PubMed ID: 8786138
PubMed ID: 10702312
Title: Molecular and biochemical characterization of rat gamma-trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis.
PubMed ID: 10702312
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8645224
Title: Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution.
PubMed ID: 8645224
DOI: 10.1042/bj3160317
PubMed ID: 8269919
Title: Human aldehyde dehydrogenase. cDNA cloning and primary structure of the enzyme that catalyzes dehydrogenation of 4-aminobutyraldehyde.
PubMed ID: 8269919
PubMed ID: 2925663
Title: Human aldehyde dehydrogenase. Purification and characterization of a third isozyme with low Km for gamma-aminobutyraldehyde.
PubMed ID: 2925663
PubMed ID: 1799975
Title: Aldehyde dehydrogenase (EC 1.2.1.3): comparison of subcellular localization of the third isozyme that dehydrogenates gamma-aminobutyraldehyde in rat, guinea pig and human liver.
PubMed ID: 1799975
PubMed ID: 2071588
Title: Human aldehyde dehydrogenase. Activity with aldehyde metabolites of monoamines, diamines, and polyamines.
PubMed ID: 2071588
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 30914451
Title: Kinetic and structural analysis of human ALDH9A1.
PubMed ID: 30914451
DOI: 10.1042/bsr20190558
Sequence Information:
- Length: 494
- Mass: 53802
- Checksum: 1E1CDF910D763BA1
- Sequence:
MSTGTFVVSQ PLNYRGGARV EPADASGTEK AFEPATGRVI ATFTCSGEKE VNLAVQNAKA AFKIWSQKSG MERCRILLEA ARIIREREDE IATMECINNG KSIFEARLDI DISWQCLEYY AGLAASMAGE HIQLPGGSFG YTRREPLGVC VGIGAWNYPF QIASWKSAPA LACGNAMVFK PSPFTPVSAL LLAEIYSEAG VPPGLFNVVQ GGAATGQFLC QHPDVAKVSF TGSVPTGMKI MEMSAKGIKP VTLELGGKSP LIIFSDCDMN NAVKGALMAN FLTQGQVCCN GTRVFVQKEI LDKFTEEVVK QTQRIKIGDP LLEDTRMGPL INRPHLERVL GFVKVAKEQG AKVLCGGDIY VPEDPKLKDG YYMRPCVLTN CRDDMTCVKE EIFGPVMSIL SFDTEAEVLE RANDTTFGLA AGVFTRDIQR AHRVVAELQA GTCFINNYNV SPVELPFGGY KKSGFGRENG RVTIEYYSQL KTVCVEMGDV ESAF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.