Genular: Defining Cellular Identity and Function

Details for: Vav2

Gene ID: 22325

Symbol: Vav2

Ensembl ID: ENSMUSG00000009621

Description: vav 2 oncogene

Associated with

Axon guidance
(R-MMU-422475)
Azathioprine adme
(R-MMU-9748787)
Cdc42 gtpase cycle
(R-MMU-9013148)
Cell death signalling via nrage, nrif and nade
(R-MMU-204998)
Dap12 interactions
(R-MMU-2172127)
Dap12 signaling
(R-MMU-2424491)
Death receptor signaling
(R-MMU-73887)
Developmental biology
(R-MMU-1266738)
Drug adme
(R-MMU-9748784)
Eph-ephrin mediated repulsion of cells
(R-MMU-3928665)
Eph-ephrin signaling
(R-MMU-2682334)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated ca+2 mobilization
(R-MMU-2871809)
Fceri mediated mapk activation
(R-MMU-2871796)
Fcgamma receptor (fcgr) dependent phagocytosis
(R-MMU-2029480)
G alpha (12/13) signalling events
(R-MMU-416482)
Gpcr downstream signalling
(R-MMU-388396)
Gpvi-mediated activation cascade
(R-MMU-114604)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
L1cam interactions
(R-MMU-373760)
Nervous system development
(R-MMU-9675108)
Nrage signals death through jnk
(R-MMU-193648)
P75 ntr receptor-mediated signalling
(R-MMU-193704)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Regulation of actin dynamics for phagocytic cup formation
(R-MMU-2029482)
Rhoa gtpase cycle
(R-MMU-8980692)
Rhob gtpase cycle
(R-MMU-9013026)
Rhoc gtpase cycle
(R-MMU-9013106)
Rhog gtpase cycle
(R-MMU-9013408)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by gpcr
(R-MMU-372790)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Signal transduction by l1
(R-MMU-445144)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Vegfr2 mediated vascular permeability
(R-MMU-5218920)
Angiogenesis
(GO:0001525)
Cell migration
(GO:0016477)
Cell projection assembly
(GO:0030031)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Epidermal growth factor receptor binding
(GO:0005154)
Guanyl-nucleotide exchange factor activity
(GO:0005085)
Intracellular signal transduction
(GO:0035556)
Lamellipodium assembly
(GO:0030032)
Metal ion binding
(GO:0046872)
Phosphotyrosine residue binding
(GO:0001784)
Plasma membrane
(GO:0005886)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Protein binding
(GO:0005515)
Regulation of gtpase activity
(GO:0043087)
Small gtpase-mediated signal transduction
(GO:0007264)

Other Information

Proteins

Guanine nucleotide exchange factor VAV2
Q7TSI6_MOUSE

Genular Protein ID: 800237277

Symbol: VAV2_MOUSE

Name: Guanine nucleotide exchange factor VAV2

UniProtKB Accession Codes:

Q60992 A2AH49

Database IDs:

Citations:

PubMed ID: 8710375

Title: Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.

PubMed ID: 8710375

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 16782872

Title: Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

PubMed ID: 16782872

DOI: 10.1128/mcb.02215-05

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22027834

Title: Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein.

PubMed ID: 22027834

DOI: 10.1074/jbc.m111.308858

Sequence Information:

Length: 868
Mass: 99915
Checksum: D18581E7EEB2DBC2
Sequence:

MEQWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQALRDG VLLCQLLHNL SPGSIDLKDI 
NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SELFDPFDLF DVRDFGKVIS AVSRLSLHSI 
AQSKGIRPFP SEETAENDDD VYRSLEELAD EHDLGEDIYD CVPCEDEGDD IYEDIIKVEV 
QQPMKMGMTE DDKRSCCLLE IQETEAKYYR TLEDIEKNYM GPLRLVLSPA DMAAVFINLE 
DLIKVHHSFL RAIDVSMMAG GSTLAKVFLE FKERLLIYGE YCSHMEHAQS TLNQLLASRE 
DFRQKVEECT LRVQDGKFKL QDLLVVPMQR VLKYHLLLKE LLSHSADRPE RQQLKEALEA 
MQDLAMYINE VKRDKETLKK ISEFQCSIEN LQVKLEEFGR PKIDGELKVR SIVNHTKQDR 
YLFLFDKVVI VCKRKGYSYE LKEVIELLFH KMTDDPMHNK DIKKWSYGFY LIHLQGKQGF 
QFFCKTEDMK RKWMEQFEMA MSNIKPDKAN ANHHSFQMYT FDKTTNCKAC KMFLRGTFYQ 
GYLCTRCGVG AHKECLEVIP PCKMSSPADV DAPGAGPGPK MVAVQNYHGN PAPPGKPVLT 
FQTGDVIELL RGDPDSPWWE GRLVQTRKSG YFPSSSVKPC PVDGRPPTGR PPSREIDYTA 
YPWFAGNMER QQTDNLLKSH ASGTYLIRER PAEAERFAIS IKFNDEVKHI KVVEKDSWIH 
ITEAKKFESL LELVEYYQCH SLKESFKQLD TTLKFPYKSR ERTTSRASSR SPASCASYNF 
SFLSPQGLSF APQAPSAPFW SVFTPRVIGT AVARYNFAAR DMRELSLREG DVVKIYSRIG 
GDQGWWKGET NGRIGWFPST YVEEEGVQ

Genular Protein ID: 3354151919

Symbol: Q7TSI6_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q7TSI6

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 829
Mass: 94258
Checksum: B27FD65E5FEFE112
Sequence:

MEQWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQALRDG VLLCQLLHNL SPGSIDLKDI 
NFRPQMSQVI SAVSRLSLHS IAQSKGIRPF PSEETAENDD DVYRSLEELA DEHDLGEDIY 
DCVPCEDEGD DIYEDIIKVE VQQPMIRYMQ KMGMTEDDKR SCCLLEIQET EAKYYRTLED 
IEKNYMGPLR LVLSPADMAA VFINLEDLIK VHHSFLRAID VSMMAGGSTL AKVFLEFKER 
LLIYGEYCSH MEHAQSTLNQ LLASREDFRQ KVEECTLRVQ DGKFKLQDLL VVPMQRVLKY 
HLLLKELLSH SADRPERQQL KEALEAMQDL AMYINEVKRD KETLKKISEF QCSIENLQVK 
LEEFGRPKID GELKVRSIVN HTKQDRYLFL FDKVVIVCKR KGYSYELKEV IELLFHKMTD 
DPMHNKDIKK SHGKMWSYGF YLIHLQGKQG FQFFCKTEDM KRKWMEQFEM AMSNIKPDKA 
NANHHSFQMY TFDKTTNCKA CKMFLRGTFY QGYLCTRCGV GAHKECLEVI PPCKMSSPAD 
VDAPGAGPGP KMVAVQNYHG NPAPPGKPVL TFQTGDVIEL LRGDPDSPWW EGRLVQTRKS 
GYFPSSSVKP CPVDGRPPTG RPPSREIDYT AYPWFAGNME RQQTDNLLKS HASGTYLIRE 
RPAEAERFAI SIKFNDEVKH IKVVEKDSWI HITEAKKFES LLSILSAIFG SPAPEGEVFE 
ALAILAGLGW RAGGVLPVSL TQGKLQAVGH YTQVPLQVSG ANHQQGLKPV SSFLRFLQLF 
FSQSSGPQLC PPGPFCSLLV SVHTAGHRHS RGQVQLCCSR HAGAVTARR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vav2

Associated with

Other Information

Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes. PubMed ID: 8710375

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. PubMed ID: 16782872

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein. PubMed ID: 22027834

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 8710375

PubMed ID: 19468303

PubMed ID: 16782872

PubMed ID: 21183079

PubMed ID: 22027834

PubMed ID: 15489334

PubMed ID: 19468303

PubMed ID: 21183079