Details for: Vax1

Gene ID: 22326

Symbol: Vax1

Ensembl ID: ENSMUSG00000006270

Description: ventral anterior homeobox 1

Associated with

  • Astrocyte differentiation
    (GO:0048708)
  • Axon guidance
    (GO:0007411)
  • Brain development
    (GO:0007420)
  • Camera-type eye development
    (GO:0043010)
  • Central nervous system development
    (GO:0007417)
  • Chromatin dna binding
    (GO:0031490)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of neuroblast proliferation
    (GO:0007406)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nervous system development
    (GO:0007399)
  • Neuroblast proliferation
    (GO:0007405)
  • Neuroepithelial cell differentiation
    (GO:0060563)
  • Neuron differentiation
    (GO:0030182)
  • Neuron migration
    (GO:0001764)
  • Nucleus
    (GO:0005634)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii intronic transcription regulatory region sequence-specific dna binding
    (GO:0001162)
  • Roof of mouth development
    (GO:0060021)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Skeletal muscle cell differentiation
    (GO:0035914)

Other Information

Genular Protein ID: 4193717894

Symbol: VAX1_MOUSE

Name: Ventral anterior homeobox 1

UniProtKB Accession Codes:

Q2NKI2 O88880

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 1 GO 23 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9636075

Title: Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain.

PubMed ID: 9636075

DOI: 10.1242/dev.125.14.2599

PubMed ID: 10421837

Title: Expression of the Vax family homeobox genes suggests multiple roles in eye development.

PubMed ID: 10421837

DOI: 10.1046/j.1365-2443.1999.00257.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10601035

Title: The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain.

PubMed ID: 10601035

DOI: 10.1101/gad.13.23.3092

PubMed ID: 21856776

Title: A novel mechanism for the transcriptional regulation of Wnt signaling in development.

PubMed ID: 21856776

DOI: 10.1101/gad.17227011

Sequence Information:

  • Length: 338
  • Mass: 35167
  • Checksum: 072986819244BB81
  • Sequence:
    • MFGKPDKMDV RCHSDTEAAR VSKNAHKESR EIKGAEGSLP AAFLKEPQGA FSGSGASEDC 
NKSKSNSSAD PDYCRRILVR DAKGSIREII LPKGLDLDRP KRTRTSFTAE QLYRLEMEFQ 
RCQYVVGRER TELARQLNLS ETQVKVWFQN RRTKQKKDQG KDSELRSVVS ETAATCSVLR 
LLEQGRLLSP PGLPALLPPC ATGALGSALR GPSLPALGAG AAAGSAAAAA AAAAATAPGP 
AGAASQHQPA VGGAPGPGPA GPGGLHAGAP TASHGLFSLP VPSLLGSVAS RLSSAPLTMA 
GSLAGNLQEL SARYLSSSAF EPYSRTNNKE GAEKKALD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.