Genular: Defining Cellular Identity and Function

Details for: Vdac2

Gene ID: 22334

Symbol: Vdac2

Ensembl ID: ENSMUSG00000021771

Description: voltage-dependent anion channel 2

Associated with

Deubiquitination
(R-MMU-5688426)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Ub-specific processing proteases
(R-MMU-5689880)
Acrosomal vesicle
(GO:0001669)
Binding of sperm to zona pellucida
(GO:0007339)
Ceramide binding
(GO:0097001)
Cholesterol binding
(GO:0015485)
Lipid binding
(GO:0008289)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial membrane
(GO:0031966)
Mitochondrial nucleoid
(GO:0042645)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrial outer membrane permeabilization
(GO:0097345)
Mitochondrion
(GO:0005739)
Monoatomic anion transmembrane transport
(GO:0098656)
Monoatomic anion transport
(GO:0006820)
Monoatomic ion transport
(GO:0006811)
Myelin sheath
(GO:0043209)
Negative regulation of intrinsic apoptotic signaling pathway
(GO:2001243)
Negative regulation of protein polymerization
(GO:0032272)
Nucleotide binding
(GO:0000166)
Oxysterol binding
(GO:0008142)
Phosphatidylcholine binding
(GO:0031210)
Pore complex
(GO:0046930)
Porin activity
(GO:0015288)
Protein binding
(GO:0005515)
Sperm midpiece
(GO:0097225)
Synaptic vesicle
(GO:0008021)
Transmembrane transport
(GO:0055085)
Voltage-gated monoatomic anion channel activity
(GO:0008308)

Other Information

Proteins

Voltage-dependent anion-selective channel protein 2

Genular Protein ID: 1181646879

Symbol: VDAC2_MOUSE

Name: Voltage-dependent anion-selective channel protein 2

UniProtKB Accession Codes:

Q60930 Q78MH6 Q99L98

Database IDs:

Citations:

PubMed ID: 8660977

Title: Isolation, characterization, and mapping of two mouse mitochondrial voltage-dependent anion channel isoforms.

PubMed ID: 8660977

DOI: 10.1006/geno.1996.0193

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22561200

Title: KLC3 is involved in sperm tail midpiece formation and sperm function.

PubMed ID: 22561200

DOI: 10.1016/j.ydbio.2012.04.026

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 33087875

Title: SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy.

PubMed ID: 33087875

DOI: 10.1038/s41418-020-00638-2

PubMed ID: 33536340

Title: ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility.

PubMed ID: 33536340

DOI: 10.1073/pnas.2018355118

PubMed ID: 34446558

Title: SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.

PubMed ID: 34446558

DOI: 10.1073/pnas.2106673118

Sequence Information:

Length: 295
Mass: 31733
Checksum: 7BBCDC625AD013C7
Sequence:

MAECCVPVCP RPMCIPPPYA DLGKAARDIF NKGFGFGLVK LDVKTKSCSG VEFSTSGSSN 
TDTGKVSGTL ETKYKWCEYG LTFTEKWNTD NTLGTEIAIE DQICQGLKLT FDTTFSPNTG 
KKSGKIKSAY KRECINLGCD VDFDFAGPAI HGSAVFGYEG WLAGYQMTFD SAKSKLTRSN 
FAVGYRTGDF QLHTNVNNGT EFGGSIYQKV CEDFDTSVNL AWTSGTNCTR FGIAAKYQLD 
PTASISAKVN NSSLIGVGYT QTLRPGVKLT LSALVDGKSF NAGGHKLGLA LELEA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vdac2

Associated with

Other Information

Isolation, characterization, and mapping of two mouse mitochondrial voltage-dependent anion channel isoforms. PubMed ID: 8660977

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

KLC3 is involved in sperm tail midpiece formation and sperm function. PubMed ID: 22561200

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753

SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy. PubMed ID: 33087875

ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility. PubMed ID: 33536340

SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice. PubMed ID: 34446558