Genular: Defining Cellular Identity and Function

Details for: Vegfb

Gene ID: 22340

Symbol: Vegfb

Ensembl ID: ENSMUSG00000024962

Description: vascular endothelial growth factor B

Associated with

Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegf binds to vegfr leading to receptor dimerization
(R-MMU-195399)
Vegf ligand-receptor interactions
(R-MMU-194313)
Angiogenesis
(GO:0001525)
Cardiac muscle contraction
(GO:0060048)
Cell differentiation
(GO:0030154)
Chemoattractant activity
(GO:0042056)
Coronary vasculature development
(GO:0060976)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Growth factor activity
(GO:0008083)
Heart development
(GO:0007507)
Heparin binding
(GO:0008201)
Identical protein binding
(GO:0042802)
Induction of positive chemotaxis
(GO:0050930)
Intracellular anatomical structure
(GO:0005622)
Membrane
(GO:0016020)
Multicellular organism development
(GO:0007275)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of neuron apoptotic process
(GO:0043524)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell division
(GO:0051781)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of mast cell chemotaxis
(GO:0060754)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of vascular endothelial growth factor receptor signaling pathway
(GO:0030949)
Positive regulation of vascular wound healing
(GO:0035470)
Protein binding
(GO:0005515)
Protein o-linked glycosylation
(GO:0006493)
Response to hypoxia
(GO:0001666)
Sprouting angiogenesis
(GO:0002040)
Vascular endothelial growth factor receptor 1 binding
(GO:0043183)
Vascular endothelial growth factor receptor signaling pathway
(GO:0048010)
Vascular endothelial growth factor signaling pathway
(GO:0038084)

Other Information

Proteins

Vascular endothelial growth factor B

Genular Protein ID: 2957633959

Symbol: VEGFB_MOUSE

Name: Vascular endothelial growth factor B

UniProtKB Accession Codes:

P49766 Q3UG04 Q5D0B1 Q64290

Database IDs:

Citations:

PubMed ID: 8607868

Title: Characterization of the murine VEGF-related factor gene.

PubMed ID: 8607868

DOI: 10.1006/bbrc.1996.0507

PubMed ID: 8702615

Title: Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform.

PubMed ID: 8702615

DOI: 10.1074/jbc.271.32.19310

PubMed ID: 8637916

Title: Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

PubMed ID: 8637916

DOI: 10.1073/pnas.93.6.2576

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11457758

Title: Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect.

PubMed ID: 11457758

DOI: 10.1161/01.cir.104.3.358

Sequence Information:

Length: 207
Mass: 21914
Checksum: 4817A5E96F6960C2
Sequence:

MSPLLRRLLL VALLQLARTQ APVSQFDGPS HQKKVVPWID VYARATCQPR EVVVPLSMEL 
MGNVVKQLVP SCVTVQRCGG CCPDDGLECV PTGQHQVRMQ ILMIQYPSSQ LGEMSLEEHS 
QCECRPKKKE SAVKPDRVAI PHHRPQPRSV PGWDSTPGAS SPADIIHPTP APGSSARLAP 
SAVNALTPGP AAAAADAAAS SIAKGGA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vegfb

Associated with

Other Information

Characterization of the murine VEGF-related factor gene. PubMed ID: 8607868

Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform. PubMed ID: 8702615

Vascular endothelial growth factor B, a novel growth factor for endothelial cells. PubMed ID: 8637916

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334