Genular: Defining Cellular Identity and Function

Details for: Vegfc

Gene ID: 22341

Symbol: Vegfc

Ensembl ID: ENSMUSG00000031520

Description: vascular endothelial growth factor C

Associated with

Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegf binds to vegfr leading to receptor dimerization
(R-MMU-195399)
Vegf ligand-receptor interactions
(R-MMU-194313)
Angiogenesis
(GO:0001525)
Animal organ morphogenesis
(GO:0009887)
Cell differentiation
(GO:0030154)
Cell population proliferation
(GO:0008283)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Chemoattractant activity
(GO:0042056)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glial cell proliferation
(GO:0014009)
Growth factor activity
(GO:0008083)
Induction of positive chemotaxis
(GO:0050930)
Membrane
(GO:0016020)
Morphogenesis of embryonic epithelium
(GO:0016331)
Multicellular organism development
(GO:0007275)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of osteoblast differentiation
(GO:0045668)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of blood vessel endothelial cell migration
(GO:0043536)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of glial cell proliferation
(GO:0060252)
Positive regulation of lymphangiogenesis
(GO:1901492)
Positive regulation of mast cell chemotaxis
(GO:0060754)
Positive regulation of mesenchymal stem cell proliferation
(GO:1902462)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of protein autophosphorylation
(GO:0031954)
Positive regulation of protein kinase activity
(GO:0045860)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of protein secretion
(GO:0050714)
Protein binding
(GO:0005515)
Regulation of vascular endothelial growth factor receptor signaling pathway
(GO:0030947)
Response to hypoxia
(GO:0001666)
Sprouting angiogenesis
(GO:0002040)
Vascular endothelial growth factor receptor 3 binding
(GO:0043185)
Vascular endothelial growth factor receptor signaling pathway
(GO:0048010)
Vascular endothelial growth factor signaling pathway
(GO:0038084)

Other Information

Proteins

Vascular endothelial growth factor C

Genular Protein ID: 947568014

Symbol: VEGFC_MOUSE

Name: Vascular endothelial growth factor C

UniProtKB Accession Codes:

P97953 C6F5S8 C6F5S9 C6F5T0 Q543R6

Database IDs:

Citations:

PubMed ID: 9012504

Title: VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development.

PubMed ID: 9012504

DOI: 10.1242/dev.122.12.3829

PubMed ID: 9247316

Title: Characterization of murine Flt4 ligand/VEGF-C.

PubMed ID: 9247316

DOI: 10.1038/sj.onc.1201191

PubMed ID: 20415667

Title: Characterization of novel VEGF (vascular endothelial growth factor)-C splicing isoforms from mouse.

PubMed ID: 20415667

DOI: 10.1042/bj20100379

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 415
Mass: 46471
Checksum: D9D3DD3CECC659D6
Sequence:

MHLLCFLSLA CSLLAAALIP SPREAPATVA AFESGLGFSE AEPDGGEVKA FEGKDLEEQL 
RSVSSVDELM SVLYPDYWKM YKCQLRKGGW QQPTLNTRTG DSVKFAAAHY NTEILKSIDN 
EWRKTQCMPR EVCIDVGKEF GAATNTFFKP PCVSVYRCGG CCNSEGLQCM NTSTGYLSKT 
LFEITVPLSQ GPKPVTISFA NHTSCRCMSK LDVYRQVHSI IRRSLPATLP QCQAANKTCP 
TNYVWNNYMC RCLAQQDFIF YSNVEDDSTN GFHDVCGPNK ELDEDTCQCV CKGGLRPSSC 
GPHKELDRDS CQCVCKNKLF PNSCGANREF DENTCQCVCK RTCPRNQPLN PGKCACECTE 
NTQKCFLKGK KFHHQTCSCY RRPCANRLKH CDPGLSFSEE VCRCVPSYWK RPHLN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vegfc

Associated with

Other Information

VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. PubMed ID: 9012504

Characterization of murine Flt4 ligand/VEGF-C. PubMed ID: 9247316

Characterization of novel VEGF (vascular endothelial growth factor)-C splicing isoforms from mouse. PubMed ID: 20415667