Genular: Defining Cellular Identity and Function

Details for: Lin7c

Gene ID: 22343

Symbol: Lin7c

Ensembl ID: ENSMUSG00000027162

Description: lin-7 homolog C, crumbs cell polarity complex component

Associated with

Dopamine neurotransmitter release cycle
(R-MMU-212676)
Neuronal system
(R-MMU-112316)
Neurotransmitter release cycle
(R-MMU-112310)
Transmission across chemical synapses
(R-MMU-112315)
Anchoring junction
(GO:0070161)
Basolateral plasma membrane
(GO:0016323)
Bicellular tight junction
(GO:0005923)
Cell-cell junction
(GO:0005911)
Cytoplasm
(GO:0005737)
Cytoskeletal protein binding
(GO:0008092)
Exocytosis
(GO:0006887)
Glutamatergic synapse
(GO:0098978)
L27 domain binding
(GO:0097016)
Maintenance of epithelial cell apical/basal polarity
(GO:0045199)
Membrane
(GO:0016020)
Morphogenesis of an epithelial sheet
(GO:0002011)
Mpp7-dlg1-lin7 complex
(GO:0097025)
Neurotransmitter secretion
(GO:0007269)
Pdz domain binding
(GO:0030165)
Plasma membrane
(GO:0005886)
Postsynaptic membrane
(GO:0045211)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein localization to basolateral plasma membrane
(GO:1903361)
Protein transport
(GO:0015031)
Synapse
(GO:0045202)
Transport vesicle membrane
(GO:0030658)

Other Information

Proteins

Protein lin-7 homolog C

Genular Protein ID: 775454358

Symbol: LIN7C_MOUSE

Name: Protein lin-7 homolog C

UniProtKB Accession Codes:

O88952

Database IDs:

Citations:

PubMed ID: 9753324

Title: A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.

PubMed ID: 9753324

DOI: 10.1016/s0092-8674(00)81736-5

PubMed ID: 10341223

Title: Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.

PubMed ID: 10341223

DOI: 10.1523/jneurosci.19-11-04189.1999

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10710551

Title: mLin-7 is localized to the basolateral surface of renal epithelia via its NH(2) terminus.

PubMed ID: 10710551

DOI: 10.1152/ajprenal.2000.278.3.f464

PubMed ID: 10753959

Title: Molecular cloning and characterization of Pals, proteins associated with mLin-7.

PubMed ID: 10753959

DOI: 10.1074/jbc.275.15.11425

PubMed ID: 10846156

Title: Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.

PubMed ID: 10846156

DOI: 10.1126/science.288.5472.1796

PubMed ID: 15466885

Title: New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.

PubMed ID: 15466885

DOI: 10.1242/jcs.01379

PubMed ID: 15494546

Title: Differential localization of the Mammalian Lin 7 (MALS/Veli) PDZ proteins in the kidney.

PubMed ID: 15494546

DOI: 10.1152/ajprenal.00235.2004

PubMed ID: 15878399

Title: Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3.

PubMed ID: 15878399

DOI: 10.1016/j.bbamcr.2004.11.008

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 197
Mass: 21834
Checksum: 7410FBFA3BD24F45
Sequence:

MAALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV REVYEHVYET 
VDISSSPEVR ANATAKATVA AFAASEGHSH PRVVELPKTE EGLGFNIMGG KEQNSPIYIS 
RIIPGGIADR HGGLKRGDQL LSVNGVSVEG EHHEKAVELL KAAQGKVKLV VRYTPKVLEE 
MESRFEKMRS AKRRQQT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lin7c

Associated with

Other Information

A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. PubMed ID: 9753324

Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex. PubMed ID: 10341223

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

mLin-7 is localized to the basolateral surface of renal epithelia via its NH(2) terminus. PubMed ID: 10710551

Molecular cloning and characterization of Pals, proteins associated with mLin-7. PubMed ID: 10753959

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. PubMed ID: 10846156

New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. PubMed ID: 15466885

Differential localization of the Mammalian Lin 7 (MALS/Veli) PDZ proteins in the kidney. PubMed ID: 15494546

Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3. PubMed ID: 15878399

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079