Genular: Defining Cellular Identity and Function

Details for: Vrk1

Gene ID: 22367

Symbol: Vrk1

Ensembl ID: ENSMUSG00000021115

Description: vaccinia related kinase 1

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Initiation of nuclear envelope (ne) reformation
(R-MMU-2995383)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prophase
(R-MMU-68875)
M phase
(R-MMU-68886)
Nuclear envelope (ne) reassembly
(R-MMU-2995410)
Nuclear envelope breakdown
(R-MMU-2980766)
Atp binding
(GO:0005524)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna damage response
(GO:0006974)
Golgi disassembly
(GO:0090166)
Golgi stack
(GO:0005795)
Histone binding
(GO:0042393)
Histone h3s10 kinase activity
(GO:0035175)
Histone h3t3 kinase activity
(GO:0072354)
Kinase activity
(GO:0016301)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Peptidyl-serine phosphorylation
(GO:0018105)
Phosphorylation
(GO:0016310)
Positive regulation of protein localization to chromatin
(GO:0120187)
Protein autophosphorylation
(GO:0046777)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Signal transduction
(GO:0007165)
Transferase activity
(GO:0016740)

Other Information

Proteins

VRK1_MOUSE
Q3UWH3_MOUSE

Genular Protein ID: 3321990891

Symbol: VRK1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q80X41 O88635 O88636 Q8C2P7 Q91YH9

Database IDs:

Citations:

PubMed ID: 9521809

Title: Molecular cloning and characterization of a novel nuclear protein kinase in mice.

PubMed ID: 9521809

DOI: 10.1006/abbi.1998.0582

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12782311

Title: Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development.

PubMed ID: 12782311

DOI: 10.1016/s0014-5793(03)00501-5

PubMed ID: 14645249

Title: Characterization of three paralogous members of the Mammalian vaccinia related kinase family.

PubMed ID: 14645249

DOI: 10.1074/jbc.m310813200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 33076429

Title: VRK1 phosphorylates Tip60/KAT5 and is required for H4K16 acetylation in response to DNA Damage.

PubMed ID: 33076429

DOI: 10.3390/cancers12102986

Sequence Information:

Length: 440
Mass: 49741
Checksum: 8318BA76A44B16BF
Sequence:

MPRVKAAQAG RPGPAKRRLA EQFAAGEVLT DMSRKEWKLG LPIGQGGFGC IYLADTNSSK 
PVGSDAPCVV KVEPSDNGPL FTELKFYQRA AKPEQIQKWI RTHKLKYLGV PKYWGSGLHD 
KNGKSYRFMI MDRFGSDLQK IYEANAKRFS RKTVLQLSLR ILDILEYIHE HEYVHGDIKA 
SNLLLSHKNP DQVYLVDYGL AYRYCPDGVH KEYKEDPKRC HDGTLEFTSI DAHKGVAPSR 
RGDLEILGYC MIQWLSGCLP WEDNLKDPNY VRDSKIRYRD NVAALMEKCF PEKNKPGEIA 
KYMESVKLLE YTEKPLYQNL RDILLQGLKA IGSKDDGKLD FSAVENGSVK TRPASKKRKK 
EAEESAVCAV EDMECSDTQV QEAAQTRSVE SQGAIHGSMS QPAAGCSSSD SSRRQQHLGL 
EQDMLRLDRR GSRTRKKAQK

Genular Protein ID: 3992492891

Symbol: Q3UWH3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UWH3

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 416
Mass: 47478
Checksum: 6E15EE21E4180E26
Sequence:

MPRVKAAQAG RPGPAKRRLA EQFAAGEVLT DMSRKEWKLG LPIGQGGFGC IYLADTNSSK 
PVGSDAPCVV KVEPSDNGPL FTELKFYQRA AKPEQIQKWI RTHKLKYLGV PKYWGSGLHD 
KNGKSYRFMI MDRFGSDLQK IYEANAKRFS RKTVLQLSLR ILDILEYIHE HEYVHGDIKA 
SNLLLSHKNP DQVYLVDYGL AYRYCPDGVH KEYKEDPKRC HDGTLEFTSI DAHKGVAPSR 
RGDLEILGYC MIQWLSGCLP WEDNLKDPNY VRDSKIRYRD NVAALMEKCF PEKNKPGEIA 
KYMESVKLLE YTEKPLYQNL RDILLQGLKA IGSKDDGKLD FSAVENGSVK TRPASKKRKK 
EAEESAVCAV EDMECSDTQV QEAAQTRSRR QQHLGLEQDM LRLDRRGSRT RKKAQK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vrk1

Associated with

Other Information

Molecular cloning and characterization of a novel nuclear protein kinase in mice. PubMed ID: 9521809

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. PubMed ID: 12782311

Characterization of three paralogous members of the Mammalian vaccinia related kinase family. PubMed ID: 14645249

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

VRK1 phosphorylates Tip60/KAT5 and is required for H4K16 acetylation in response to DNA Damage. PubMed ID: 33076429

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073