Genular: Defining Cellular Identity and Function

Details for: Vtn

Gene ID: 22370

Symbol: Vtn

Ensembl ID: ENSMUSG00000017344

Description: vitronectin

Associated with

Complement cascade
(R-MMU-166658)
Ecm proteoglycans
(R-MMU-3000178)
Elastic fibre formation
(R-MMU-1566948)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Integrin cell surface interactions
(R-MMU-216083)
Molecules associated with elastic fibres
(R-MMU-2129379)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Regulation of complement cascade
(R-MMU-977606)
Syndecan interactions
(R-MMU-3000170)
Basement membrane
(GO:0005604)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion
(GO:0007155)
Cell adhesion mediated by integrin
(GO:0033627)
Cell migration
(GO:0016477)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen binding
(GO:0005518)
Endodermal cell differentiation
(GO:0035987)
Endoplasmic reticulum
(GO:0005783)
Extracellular matrix
(GO:0031012)
Extracellular matrix binding
(GO:0050840)
Extracellular matrix organization
(GO:0030198)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi lumen
(GO:0005796)
Heparin binding
(GO:0008201)
Identical protein binding
(GO:0042802)
Immune response
(GO:0006955)
Integrin binding
(GO:0005178)
Intracellular membrane-bounded organelle
(GO:0043231)
Liver regeneration
(GO:0097421)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of fibrinolysis
(GO:0051918)
Oligodendrocyte differentiation
(GO:0048709)
Peptidase inhibitor complex
(GO:1904090)
Polysaccharide binding
(GO:0030247)
Positive regulation of cell-substrate adhesion
(GO:0010811)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of protein binding
(GO:0032092)
Positive regulation of receptor-mediated endocytosis
(GO:0048260)
Positive regulation of smooth muscle cell migration
(GO:0014911)
Protein complex involved in cell-matrix adhesion
(GO:0098637)
Protein polymerization
(GO:0051258)
Regulation of cell adhesion
(GO:0030155)
Rough endoplasmic reticulum lumen
(GO:0048237)
Scavenger receptor activity
(GO:0005044)
Smooth muscle cell-matrix adhesion
(GO:0061302)

Other Information

Proteins

Vitronectin

Genular Protein ID: 2607138155

Symbol: VTNC_MOUSE

Name: Vitronectin

UniProtKB Accession Codes:

P29788 Q5SYG4 Q8VII4 Q91X32 Q9D080

Database IDs:

Citations:

PubMed ID: 7505250

Title: Organization of the gene encoding mouse vitronectin.

PubMed ID: 7505250

DOI: 10.1016/0378-1119(93)90113-h

PubMed ID: 1719529

Title: Detection of vitronectin mRNA in tissues and cells of the mouse.

PubMed ID: 1719529

DOI: 10.1073/pnas.88.21.9402

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1372829

Title: Vitronectin diversity in evolution but uniformity in ligand binding and size of the core polypeptide.

PubMed ID: 1372829

DOI: 10.1016/0167-4838(92)90417-c

PubMed ID: 17330941

Title: Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.

PubMed ID: 17330941

DOI: 10.1021/pr0604559

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 478
Mass: 54849
Checksum: EB0C772F8BD6A166
Sequence:

MAPLRPFFIL ALVAWVSLAD QESCKGRCTQ GFMASKKCQC DELCTYYQSC CADYMEQCKP 
QVTRGDVFTM PEDDYWSYDY VEEPKNNTNT GVQPENTSPP GDLNPRTDGT LKPTAFLDPE 
EQPSTPAPKV EQQEEILRPD TTDQGTPEFP EEELCSGKPF DAFTDLKNGS LFAFRGQYCY 
ELDETAVRPG YPKLIQDVWG IEGPIDAAFT RINCQGKTYL FKGSQYWRFE DGVLDPGYPR 
NISEGFSGIP DNVDAAFALP AHRYSGRERV YFFKGKQYWE YEFQQQPSQE ECEGSSLSAV 
FEHFALLQRD SWENIFELLF WGRSSDGARE PQFISRNWHG VPGKVDAAMA GRIYVTGSLS 
HSAQAKKQKS KRRSRKRYRS RRGRGHRRSQ SSNSRRSSRS IWFSLFSSEE SGLGTYNNYD 
YDMDWLVPAT CEPIQSVYFF SGDKYYRVNL RTRRVDSVNP PYPRSIAQYW LGCPTSEK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vtn

Associated with

Other Information

Organization of the gene encoding mouse vitronectin. PubMed ID: 7505250

Detection of vitronectin mRNA in tissues and cells of the mouse. PubMed ID: 1719529

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Vitronectin diversity in evolution but uniformity in ligand binding and size of the core polypeptide. PubMed ID: 1372829

Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. PubMed ID: 17330941

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079