Genular: Defining Cellular Identity and Function

Details for: Wnt10b

Gene ID: 22410

Symbol: Wnt10b

Ensembl ID: ENSMUSG00000022996

Description: wingless-type MMTV integration site family, member 10B

Associated with

Signaling by wnt
(R-MMU-195721)
Wnt ligand biogenesis and trafficking
(R-MMU-3238698)
Anagen
(GO:0042640)
Animal organ morphogenesis
(GO:0009887)
Bone trabecula formation
(GO:0060346)
Canonical wnt signaling pathway
(GO:0060070)
Cell-cell signaling
(GO:0007267)
Cell fate commitment
(GO:0045165)
Cell population proliferation
(GO:0008283)
Cellular response to camp
(GO:0071320)
Cellular response to organic cyclic compound
(GO:0071407)
Cellular response to organic substance
(GO:0071310)
Cellular response to parathyroid hormone stimulus
(GO:0071374)
Cytokine activity
(GO:0005125)
Epithelial cell differentiation
(GO:0030855)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fat cell differentiation
(GO:0045444)
Frizzled binding
(GO:0005109)
Fungiform papilla development
(GO:0061196)
G2/m transition of mitotic cell cycle
(GO:0000086)
Hematopoietic stem cell proliferation
(GO:0071425)
Lipid metabolic process
(GO:0006629)
Multicellular organism development
(GO:0007275)
Myoblast development
(GO:0048627)
Myoblast differentiation involved in skeletal muscle regeneration
(GO:0014835)
Negative regulation of cold-induced thermogenesis
(GO:0120163)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of fat cell differentiation
(GO:0045599)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron differentiation
(GO:0030182)
Osteoblast differentiation
(GO:0001649)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of bone mineralization
(GO:0030501)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of epithelial cell differentiation
(GO:0030858)
Positive regulation of g2/m transition of mitotic cell cycle
(GO:0010971)
Positive regulation of hematopoietic stem cell proliferation
(GO:1902035)
Positive regulation of ossification
(GO:0045778)
Positive regulation of osteoblast differentiation
(GO:0045669)
Positive regulation of rna polymerase ii transcription preinitiation complex assembly
(GO:0045899)
Positive regulation of t cell differentiation
(GO:0045582)
Positive regulation of timing of anagen
(GO:0051885)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein stabilization
(GO:0050821)
Regulation of cell cycle
(GO:0051726)
Regulation of fat cell differentiation
(GO:0045598)
Regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032434)
Regulation of protein metabolic process
(GO:0051246)
Regulation of skeletal muscle tissue development
(GO:0048641)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Sensory perception of taste
(GO:0050909)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Skeletal muscle fiber development
(GO:0048741)
Skeletal muscle tissue regeneration
(GO:0043403)
Smoothened signaling pathway
(GO:0007224)
T cell differentiation
(GO:0030217)
Transcription by rna polymerase ii
(GO:0006366)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Protein Wnt-10b
Q1RME7_MOUSE

Genular Protein ID: 2346243379

Symbol: WN10B_MOUSE

Name: Protein Wnt-10b

UniProtKB Accession Codes:

P48614 P70702

Database IDs:

Citations:

PubMed ID: 7892260

Title: Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice.

PubMed ID: 7892260

DOI: 10.1073/pnas.92.6.2268

PubMed ID: 8682303

Title: The mouse Wnt-10B gene isolated from helper T cells is widely expressed and a possible oncogene in BR6 mouse mammary tumorigenesis.

PubMed ID: 8682303

DOI: 10.1016/0378-1119(96)00109-6

PubMed ID: 8875992

Title: Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults.

PubMed ID: 8875992

PubMed ID: 21447090

Title: The role of WNT10B in physiology and disease.

PubMed ID: 21447090

DOI: 10.1111/j.1748-1716.2011.02296.x

Sequence Information:

Length: 389
Mass: 43119
Checksum: F990AB33B7C84633
Sequence:

MLEEPRSRPP PLGLAGLLFL ALFSRALSNE ILGLKLPGEP PLTANTVCLT LSGLSKRQLG 
LCLRSPDVTA SALQGLHIAV HECQHQLRDQ RWNCSALEGG GRLPHHSAIL KRGFRESAFS 
FSMLAAGVMH AVATACSLGK LVSCGCGWKG SGEQDRLRAK LLQLQALSRG KTFPISQPSP 
VPGSVPSPGP QDTWEWGGCN HDMDFGEKFS RDFLDSREAP RDIQARMRIH NNRVGRQVVT 
ENLKRKCKCH GTSGSCQFKT CWRAAPEFRA IGAALRERLS RAIFIDTHNR NSGAFQPRLR 
PRRLSGELVY FEKSPDFCER DPTLGSPGTR GRACNKTSRL LDGCGSLCCG RGHNVLRQTR 
VERCHCRFHW CCYVLCDECK VTEWVNVCK

Genular Protein ID: 3456543157

Symbol: Q1RME7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q1RME7

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 173
Mass: 18471
Checksum: AE9CFD0FF7C027A5
Sequence:

MLEEPRSRPP PLGLAGLLFL ALFSRALSNE ILGLKLPGEP PLTANTVCLT LSGLSKRQLG 
LCLRSPDVTA SALQGLHIAV HECQHQLRDQ RWNCSALEGG GRLPHHSAIL KRGFRESAFS 
FSMLAAGVMH AVATACSLGK LVSCGCGWKG SGRLPGTSRR ECGSTTTGWD ARW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Wnt10b

Associated with

Other Information

Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice. PubMed ID: 7892260

The mouse Wnt-10B gene isolated from helper T cells is widely expressed and a possible oncogene in BR6 mouse mammary tumorigenesis. PubMed ID: 8682303

Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults. PubMed ID: 8875992

The role of WNT10B in physiology and disease. PubMed ID: 21447090

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334