Genular: Defining Cellular Identity and Function

Details for: Wnt2

Gene ID: 22413

Symbol: Wnt2

Ensembl ID: ENSMUSG00000010797

Description: wingless-type MMTV integration site family, member 2

Associated with

Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
Wnt ligand biogenesis and trafficking
(R-MMU-3238698)
Atrial cardiac muscle tissue morphogenesis
(GO:0055009)
Canonical wnt signaling pathway
(GO:0060070)
Cardiac epithelial to mesenchymal transition
(GO:0060317)
Cardiac muscle cell proliferation
(GO:0060038)
Cell-cell signaling
(GO:0007267)
Cell fate commitment
(GO:0045165)
Cell proliferation in midbrain
(GO:0033278)
Collagen-containing extracellular matrix
(GO:0062023)
Cytokine activity
(GO:0005125)
Cytoplasm
(GO:0005737)
Epithelial cell proliferation
(GO:0050673)
Epithelial cell proliferation involved in lung morphogenesis
(GO:0060502)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Frizzled binding
(GO:0005109)
Labyrinthine layer blood vessel development
(GO:0060716)
Lung induction
(GO:0060492)
Mesenchymal cell proliferation
(GO:0010463)
Midbrain dopaminergic neuron differentiation
(GO:1904948)
Multicellular organism development
(GO:0007275)
Neuron differentiation
(GO:0030182)
Positive regulation of cardiac muscle cell proliferation
(GO:0060045)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of epithelial cell proliferation involved in lung morphogenesis
(GO:0060501)
Positive regulation of fibroblast proliferation
(GO:0048146)
Positive regulation of mesenchymal cell proliferation
(GO:0002053)
Positive regulation of neurogenesis
(GO:0050769)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Receptor ligand activity
(GO:0048018)
Signaling receptor binding
(GO:0005102)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Protein Wnt-2
Q8BRC7_MOUSE

Genular Protein ID: 2224463122

Symbol: WNT2_MOUSE

Name: Protein Wnt-2

UniProtKB Accession Codes:

P21552 Q9CZW3

Database IDs:

Citations:

PubMed ID: 2693041

Title: Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene.

PubMed ID: 2693041

DOI: 10.1242/dev.107.3.643

PubMed ID: 2279700

Title: Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.

PubMed ID: 2279700

DOI: 10.1101/gad.4.12b.2319

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19686689

Title: Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut.

PubMed ID: 19686689

DOI: 10.1016/j.devcel.2009.06.005

PubMed ID: 20018874

Title: Wnt2 regulates progenitor proliferation in the developing ventral midbrain.

PubMed ID: 20018874

DOI: 10.1074/jbc.m109.079822

PubMed ID: 21704027

Title: Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression.

PubMed ID: 21704027

DOI: 10.1016/j.ydbio.2011.06.011

Sequence Information:

Length: 360
Mass: 40482
Checksum: 5E37644D3815EEAD
Sequence:

MNVPLGGIWL WLPLLLTWLT PEVSSSWWYM RATGGSSRVM CDNVPGLVSR QRQLCHRHPD 
VMRAIGLGVA EWTAECQHQF RQHRWNCNTL DRDHSLFGRV LLRSSRESAF VYAISSAGVV 
FAITRACSQG ELKSCSCDPK KKGSAKDSKG TFDWGGCSDN IDYGIKFARA FVDAKERKGK 
DARALMNLHN NRAGRKAVKR FLKQECKCHG VSGSCTLRTC WLAMADFRKT GDYLWRKYNG 
AIQVVMNQDG TGFTVANKRF KKPTKNDLVY FENSPDYCIR DREAGSLGTA GRVCNLTSRG 
MDSCEVMCCG RGYDTSHVTR MTKCECKFHW CCAVRCQDCL EALDVHTCKA PKSADWATPT

Genular Protein ID: 3600739479

Symbol: Q8BRC7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BRC7

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 360
Mass: 40424
Checksum: C711BF208ECCCA3E
Sequence:

MNVPLGGIWL WLPLLLTWLT PEVSSSWWYM RATGGSSRVM CDNVPGLVSR QRQLCHRHPD 
VMRAIGLGVA EWTAECQHQF RQHRWNCNTL DRDHSLFGRV LLRSSRESAF VYAISSAGVV 
FAITRACSQG ELKSCSCDPK KKGSAKDSKG TFDWGGCSDN IDYGIKFARA FVDAKERKGK 
DARALMNLHN NRAGRKAVKR FLKQECKCHG VSGSCTLRTC WLAMADFRKT GDYLWRKYNG 
AIQVVMNQGG TGFTVANKRF KKPTKNDLVY FENSPDYCIR DREAGSLGTA GRVCNLTSRG 
MDSCEVMCCG RGYDTSHVTR MTKCECKFHW CCAVRCQDCL EALDVHTCKA PKSADWATPT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Wnt2

Associated with

Other Information

Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene. PubMed ID: 2693041

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. PubMed ID: 2279700

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. PubMed ID: 19686689

Wnt2 regulates progenitor proliferation in the developing ventral midbrain. PubMed ID: 20018874

Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression. PubMed ID: 21704027

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073