Genular: Defining Cellular Identity and Function

Details for: Wnt3

Gene ID: 22415

Symbol: Wnt3

Ensembl ID: ENSMUSG00000000125

Description: wingless-type MMTV integration site family, member 3

Associated with

Signaling by wnt
(R-MMU-195721)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Wnt ligand biogenesis and trafficking
(R-MMU-3238698)
Anatomical structure formation involved in morphogenesis
(GO:0048646)
Animal organ morphogenesis
(GO:0009887)
Anterior/posterior axis specification
(GO:0009948)
Anterior/posterior pattern specification
(GO:0009952)
Axon guidance
(GO:0007411)
Canonical wnt signaling pathway
(GO:0060070)
Canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
(GO:0044338)
Cell-cell signaling
(GO:0007267)
Cell fate commitment
(GO:0045165)
Cell morphogenesis
(GO:0000902)
Cytokine activity
(GO:0005125)
Dorsal/ventral axis specification
(GO:0009950)
Embryonic forelimb morphogenesis
(GO:0035115)
Embryonic hindlimb morphogenesis
(GO:0035116)
Endoplasmic reticulum lumen
(GO:0005788)
Extracellular matrix
(GO:0031012)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Frizzled binding
(GO:0005109)
Gamete generation
(GO:0007276)
Gene expression
(GO:0010467)
Head morphogenesis
(GO:0060323)
Limb bud formation
(GO:0060174)
Limb development
(GO:0060173)
Mesoderm formation
(GO:0001707)
Midbrain dopaminergic neuron differentiation
(GO:1904948)
Multicellular organism development
(GO:0007275)
Negative regulation of axon extension involved in axon guidance
(GO:0048843)
Neuron differentiation
(GO:0030182)
Positive regulation of collateral sprouting in absence of injury
(GO:0048697)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of osteoblast differentiation
(GO:0045669)
Positive regulation of wnt signaling pathway
(GO:0030177)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Receptor ligand activity
(GO:0048018)
Regulation of mesenchymal stem cell differentiation
(GO:2000739)
Regulation of neurogenesis
(GO:0050767)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Spemann organizer formation at the anterior end of the primitive streak
(GO:0060064)
Stem cell proliferation
(GO:0072089)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Proto-oncogene Wnt-3
Q3TQ59_MOUSE

Genular Protein ID: 473895689

Symbol: WNT3_MOUSE

Name: Proto-oncogene Wnt-3

UniProtKB Accession Codes:

P17553

Database IDs:

Citations:

PubMed ID: 2162045

Title: Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain.

PubMed ID: 2162045

DOI: 10.1073/pnas.87.12.4519

PubMed ID: 10431240

Title: Requirement for Wnt3 in vertebrate axis formation.

PubMed ID: 10431240

DOI: 10.1038/11932

PubMed ID: 10866835

Title: The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family.

PubMed ID: 10866835

DOI: 10.1046/j.1432-1033.2000.01478.x

PubMed ID: 12569130

Title: Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge.

PubMed ID: 12569130

DOI: 10.1101/gad.1044903

PubMed ID: 19841259

Title: Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

PubMed ID: 19841259

DOI: 10.1073/pnas.0904894106

Sequence Information:

Length: 355
Mass: 39659
Checksum: F31CFD65E43E9C17
Sequence:

MEPHLLGLLL GLLLSGTRVL AGYPIWWSLA LGQQYTSLAS QPLLCGSIPG LVPKQLRFCR 
NYIEIMPSVA EGVKLGIQEC QHQFRGRRWN CTTIDDSLAI FGPVLDKATR ESAFVHAIAS 
AGVAFAVTRS CAEGTSTICG CDSHHKGPPG EGWKWGGCSE DADFGVLVSR EFADARENRP 
DARSAMNKHN NEAGRTTILD HMHLKCKCHG LSGSCEVKTC WWAQPDFRAI GDFLKDKYDS 
ASEMVVEKHR ESRGWVETLR AKYALFKPPT ERDLVYYENS PNFCEPNPET GSFGTRDRTC 
NVTSHGIDGC DLLCCGRGHN TRTEKRKEKC HCVFHWCCYV SCQECIRIYD VHTCK

Genular Protein ID: 2303998858

Symbol: Q3TQ59_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TQ59

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 290
Mass: 32497
Checksum: E2D2526C150D1389
Sequence:

MPSVAEGVKL GIQECQHQFR GRRWNCTTID DSLAIFGPVL DKATRESAFV HAIASAGVAF 
AVTRSCAEGT STICGCDSHH KGPPGEGWKW GGCSEDADFG VLVSREFADA RENRPDARSA 
MNKHNNEAGR TTILDHMHLK CKCHGLSGSC EVKTCWWAQP DFRAIGDFLK DKYDSASEMV 
VEKHRESRGW VETLRAKYAL FKPPTERDLV YYENSPNFCE PNPETGSFGT RDRTCNVTSH 
GIDGCDLLCC GRGHNTRTEK RKEKCHCVFH WCCYVSCQEC IRIYDVHTCK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Wnt3

Associated with

Other Information

Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. PubMed ID: 2162045

Requirement for Wnt3 in vertebrate axis formation. PubMed ID: 10431240

The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. PubMed ID: 10866835

Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. PubMed ID: 12569130

Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. PubMed ID: 19841259

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073