Genular: Defining Cellular Identity and Function

Details for: Wt1

Gene ID: 22431

Symbol: Wt1

Ensembl ID: ENSMUSG00000016458

Description: WT1 transcription factor

Associated with

Adrenal cortex formation
(GO:0035802)
Adrenal gland development
(GO:0030325)
Apoptotic process
(GO:0006915)
Branching involved in ureteric bud morphogenesis
(GO:0001658)
C2h2 zinc finger domain binding
(GO:0070742)
Camera-type eye development
(GO:0043010)
Cardiac muscle cell fate commitment
(GO:0060923)
Cellular response to gonadotropin stimulus
(GO:0071371)
Coronary vasculature development
(GO:0060976)
Diaphragm development
(GO:0060539)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Double-stranded dna binding
(GO:0003690)
Double-stranded methylated dna binding
(GO:0010385)
Epithelial cell differentiation
(GO:0030855)
Flagellated sperm motility
(GO:0030317)
Germ cell development
(GO:0007281)
Glomerular basement membrane development
(GO:0032836)
Glomerulus development
(GO:0032835)
Gonad development
(GO:0008406)
Heart development
(GO:0007507)
Hemi-methylated dna-binding
(GO:0044729)
Kidney development
(GO:0001822)
Male genitalia development
(GO:0030539)
Male gonad development
(GO:0008584)
Mesenchymal cell apoptotic process involved in metanephros development
(GO:1900200)
Mesenchymal to epithelial transition
(GO:0060231)
Mesonephros development
(GO:0001823)
Metal ion binding
(GO:0046872)
Metanephric comma-shaped body morphogenesis
(GO:0072278)
Metanephric mesenchyme development
(GO:0072075)
Metanephric s-shaped body morphogenesis
(GO:0072284)
Metanephros development
(GO:0001656)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of female gonad development
(GO:2000195)
Negative regulation of mesenchymal cell apoptotic process involved in metanephros development
(GO:1900212)
Negative regulation of metanephric glomerular mesangial cell proliferation
(GO:0072302)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of translation
(GO:0017148)
Nucleus
(GO:0005634)
Podocyte development
(GO:0072015)
Podocyte differentiation
(GO:0072112)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of dna methylation
(GO:1905643)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of heart growth
(GO:0060421)
Positive regulation of male gonad development
(GO:2000020)
Positive regulation of metanephric ureteric bud development
(GO:2001076)
Positive regulation of mirna transcription
(GO:1902895)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Posterior mesonephric tubule development
(GO:0072166)
Protein binding
(GO:0005515)
Regulation of animal organ formation
(GO:0003156)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of gene expression
(GO:0010468)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna splicing
(GO:0008380)
Seminiferous tubule development
(GO:0072520)
Sequence-specific dna binding
(GO:0043565)
Sertoli cell development
(GO:0060009)
Sex determination
(GO:0007530)
Single fertilization
(GO:0007338)
Spermatogenesis
(GO:0007283)
Thorax and anterior abdomen determination
(GO:0007356)
Transcription cis-regulatory region binding
(GO:0000976)
Ureteric bud development
(GO:0001657)
Vasculogenesis
(GO:0001570)
Visceral serous pericardium development
(GO:0061032)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Q199A7_MOUSE

Genular Protein ID: 331131667

Symbol: Q199A7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q199A7

Database IDs:

Citations:

PubMed ID: 16698800

Title: N-terminally truncated WT1 protein with oncogenic properties overexpressed in leukemia.

PubMed ID: 16698800

DOI: 10.1074/jbc.M512391200

Sequence Information:

Length: 305
Mass: 34756
Checksum: 3EE51D0C7ED621A5
Sequence:

MEKGYSTVTF DGAPSYGHTP SHHAAQFPNH SFKHEDPMGQ QGSLGEQQYS VPPPVYGCHT 
PTDSCTGSQA LLLRTPYSSD NLYQMTSQLE CMTWNQMNLG ATLKGMAAGS SSSVKWTEGQ 
SNHGIGYESE NHTAPILCGA QYRIHTHGVF RGIQDVRRVS GVAPTLVRSA SETSEKRPFM 
CAYPGCNKRY FKLSHLQMHS RKHTGEKPYQ CDFKDCERRF SRSDQLKRHQ RRHTGVKPFQ 
CKTCQRKFSR SDHLKTHTRT HTGKTSEKPF SCRWHSCQKK FARSDELVRH HNMHQRNMTK 
LHVAL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Wt1

Associated with

Other Information

N-terminally truncated WT1 protein with oncogenic properties overexpressed in leukemia. PubMed ID: 16698800

Database document:

PubMed ID: 16698800