Genular: Defining Cellular Identity and Function

Details for: Xdh

Gene ID: 22436

Symbol: Xdh

Ensembl ID: ENSMUSG00000024066

Description: xanthine dehydrogenase

Associated with

Adaptive immune system
(R-MMU-1280218)
Azathioprine adme
(R-MMU-9748787)
Butyrophilin (btn) family interactions
(R-MMU-8851680)
Drug adme
(R-MMU-9748784)
Immune system
(R-MMU-168256)
Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
Nucleotide catabolism
(R-MMU-8956319)
Purine catabolism
(R-MMU-74259)
2 iron, 2 sulfur cluster binding
(GO:0051537)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Adenosine catabolic process
(GO:0006154)
Allantoin metabolic process
(GO:0000255)
Amide catabolic process
(GO:0043605)
Amp catabolic process
(GO:0006196)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Damp catabolic process
(GO:0046059)
Deoxyadenosine catabolic process
(GO:0006157)
Deoxyguanosine catabolic process
(GO:0006161)
Deoxyinosine catabolic process
(GO:0006149)
Dgmp catabolic process
(GO:0046055)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fad binding
(GO:0071949)
Flavin adenine dinucleotide binding
(GO:0050660)
Gmp catabolic process
(GO:0046038)
Guanine catabolic process
(GO:0006147)
Hypoxanthine catabolic process
(GO:0009114)
Hypoxanthine dehydrogenase activity
(GO:0070674)
Hypoxanthine oxidase activity
(GO:0070675)
Identical protein binding
(GO:0042802)
Imp catabolic process
(GO:0006204)
Inosine catabolic process
(GO:0006148)
Iron-sulfur cluster assembly
(GO:0016226)
Iron-sulfur cluster binding
(GO:0051536)
Iron ion binding
(GO:0005506)
Lactation
(GO:0007595)
Metal ion binding
(GO:0046872)
Molybdenum ion binding
(GO:0030151)
Molybdopterin cofactor binding
(GO:0043546)
Negative regulation of endothelial cell differentiation
(GO:0045602)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of protein phosphorylation
(GO:0001933)
Negative regulation of vascular endothelial growth factor signaling pathway
(GO:1900747)
Negative regulation of vasculogenesis
(GO:2001213)
Nitrite reductase (no-forming) activity
(GO:0050421)
Oxidoreductase activity
(GO:0016491)
Peroxisome
(GO:0005777)
Positive regulation of p38mapk cascade
(GO:1900745)
Positive regulation of reactive oxygen species metabolic process
(GO:2000379)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of epithelial cell differentiation
(GO:0030856)
Response to aluminum ion
(GO:0010044)
Sarcoplasmic reticulum
(GO:0016529)
Xanthine catabolic process
(GO:0009115)
Xanthine dehydrogenase activity
(GO:0004854)
Xanthine oxidase activity
(GO:0004855)

Other Information

Proteins

Xanthine dehydrogenase/oxidase
Q9CVF2_MOUSE

Genular Protein ID: 3981935709

Symbol: XDH_MOUSE

Name: Xanthine dehydrogenase/oxidase

UniProtKB Accession Codes:

Q00519 E9QLM9

Database IDs:

Citations:

PubMed ID: 7835888

Title: Chromosomal mapping, isolation, and characterization of the mouse xanthine dehydrogenase gene.

PubMed ID: 7835888

DOI: 10.1006/geno.1994.1515

PubMed ID: 1590774

Title: Molecular cloning of a cDNA coding for mouse liver xanthine dehydrogenase. Regulation of its transcript by interferons in vivo.

PubMed ID: 1590774

DOI: 10.1042/bj2830863

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 8541302

Title: Carboxy-terminal cytoplasmic domain of mouse butyrophilin specifically associates with a 150-kDa protein of mammary epithelial cells and milk fat globule membrane.

PubMed ID: 8541302

DOI: 10.1016/0304-4165(95)00102-6

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1335
Mass: 146562
Checksum: 56AD3E0C75E00F98
Sequence:

MTRTTVDELV FFVNGKKVVE KNADPETTLL VYLRRKLGLC GTKLGCGEGG CGACTVMISK 
YDRLQNKIVH FSVNACLTPI CSLHHVAVTT VEGIGNTKKL HPVQERIAKS HGSQCGFCTP 
GIVMSMYTLL RNKPEPTVEE IENAFQGNLC RCTGYRPILQ GFRTFAKDGG CCGGSGNNPN 
CCMSQTKDQT IAPSSSLFNP EDFKPLDPTQ EPIFPPELLR LKDTPRKTLR FEGERVTWIQ 
VSTMEELLDL KAQHPDAKLV VGNTEIGIEM KFKNMLFPLI ICPAWILELT SVAHGPEGIS 
FGAACPLSLV ESVLADAIAT LPEQRTEVFR GVMEQLRWFA GKQVKSVASI GGNIITASPI 
SDLNPVLMAS RAKLTLASRG TKRTVWMDHT FFPGYRRTLL SPEEILVSIV IPYSRKGEFF 
SAFKQASRRE DDIAKVTSGM RVLFKPGTTE VQELSLCFGG MADRTVSALK TTPKQLSKSW 
NEELLQDVCA GLAEELHLAP DAPGGMVEFR RTLTLSFFFK FYLTVLQKLG RADLEGMCGK 
LDPTFASATL LFQKDPPANV QLFQEVPKGQ SEEDMVGRPM PHLAADMQAS GEAVYCDDIP 
RYENELSLRL VTSTRAHAKI MSIDTSEAKK VPGFVCFLTS EDVPGSNITG IFNDETVFAK 
DEVTCVGHII GAVVADTPEH AHRAARGVKI TYEDLPAIIT IQDAIKNNSF YGPEVKIEKG 
DLKKGFSEAD NVVSGELYIG GQEHFYLETH CTIAVPKGEA GEMELFVSTQ NTMKTQSFIA 
KMLGVPDNRI VVRVKRMGGG FGGKETRSTL ISTAVALAAY KTGRPVRCML DRDEDMLITG 
GRHPFLAKYK VGFMKTGTIV ALEVAHFSNG GNSEDLSRSI MERAVFHMDN AYKIPNIRGT 
GRICKTNLPS NTAFRGFGGP QGMLIAEYWM SEVAVTCGLP AEEVRRKNMY KEGDLTHFNQ 
KLEGFTLPRC WDECIASSQY QARKMEVEKF NRENCWKKRG LCIIPTKFGI SFTLSFLNQG 
GALVHVYTDG SVLLTHGGTE MGQGLHTKMV QVASRALKIP TSKIHITETS TNTVPNTSPT 
AASASADLNG QAIYEACQTI LKRLEPFKKK NPSGSWESWV MDAYTSAVSL SATGFYKTPN 
LGYSFETNSG NPFHYFSYGV ACSEVEIDCL TGDHKNLRTD IVMDVGSSLN PAIDIGQVEG 
AFVQGLGLFT MEELHYSPEG SLHTRGPSTY KIPAFGSIPI EFRVSLLRDC PNKRAIYASK 
AVGEPPLFLA SSIFFAIKDA IRAARAQHGD SNAKQLFQLD SPATPEKIRN ACVDQFTTLC 
ATGTPENCKS WSVRI

Genular Protein ID: 3042929100

Symbol: Q9CVF2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CVF2

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 330
Mass: 35662
Checksum: 2392CDD0B14F345D
Sequence:

TKFGISFTLS FLNQGGALVH VYTDGSVLLT HGGTEMGQGL HTKMVQVASR ALKIPTSKIH 
ITETSTNTVP NTSPTAASAS ADLNGQAIYE ACQTILKRLE PFKKKNPSGS WESWVMDAYT 
SAVSLSATGF YKTPNLGYSF ETNSGNPFHY FSYGVACSEV EIDCLTGDHK NLRTDIVMDV 
GSSLNPAIDI GQVEGAFVQG LGLFTMEELH YSPEGSLHTR GPSTYKIPAF GSIPIEFRVS 
LLRDCPNKRA IYASKAVGEP PLFLASSIFF AIKDAIRAAR AQHGDSNAKQ LFQLDSPATP 
EKIRNACVDQ FTTLCATGTP ENCKSWSVRI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Xdh

Associated with

Other Information

Chromosomal mapping, isolation, and characterization of the mouse xanthine dehydrogenase gene. PubMed ID: 7835888

Molecular cloning of a cDNA coding for mouse liver xanthine dehydrogenase. Regulation of its transcript by interferons in vivo. PubMed ID: 1590774

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Carboxy-terminal cytoplasmic domain of mouse butyrophilin specifically associates with a 150-kDa protein of mammary epithelial cells and milk fat globule membrane. PubMed ID: 8541302

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073