Genular: Defining Cellular Identity and Function

Details for: Xpa

Gene ID: 22590

Symbol: Xpa

Ensembl ID: ENSMUSG00000028329

Description: xeroderma pigmentosum, complementation group A

Associated with

Dual incision in gg-ner
(R-MMU-5696400)
Dual incision in tc-ner
(R-MMU-6782135)
Formation of incision complex in gg-ner
(R-MMU-5696395)
Formation of tc-ner pre-incision complex
(R-MMU-6781823)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Nucleotide excision repair
(R-MMU-5696398)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-MMU-6781827)
Base-excision repair
(GO:0006284)
Damaged dna binding
(GO:0003684)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Dna replication factor a complex
(GO:0005662)
Intercellular bridge
(GO:0045171)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Metal ion binding
(GO:0046872)
Multicellular organism growth
(GO:0035264)
Nucleoplasm
(GO:0005654)
Nucleotide-excision repair
(GO:0006289)
Nucleotide-excision repair, dna damage recognition
(GO:0000715)
Nucleotide-excision repair factor 1 complex
(GO:0000110)
Nucleotide-excision repair involved in interstrand cross-link repair
(GO:1901255)
Nucleus
(GO:0005634)
Positive regulation of transcription initiation by rna polymerase ii
(GO:0060261)
Protein domain specific binding
(GO:0019904)
Protein homodimerization activity
(GO:0042803)
Protein localization to nucleus
(GO:0034504)
Regulation of autophagy
(GO:0010506)
Response to oxidative stress
(GO:0006979)
Response to toxic substance
(GO:0009636)
Response to uv
(GO:0009411)
Sequence-specific double-stranded dna binding
(GO:1990837)
Uv-damage excision repair
(GO:0070914)
Uv protection
(GO:0009650)

Other Information

Proteins

DNA repair protein complementing XP-A cells homolog

Genular Protein ID: 3907499118

Symbol: XPA_MOUSE

Name: DNA repair protein complementing XP-A cells homolog

UniProtKB Accession Codes:

Q64267 A2ALZ7 Q9CVA0

Database IDs:

Citations:

PubMed ID: 8127648

Title: Cloning and characterization of the mouse XPAC gene.

PubMed ID: 8127648

DOI: 10.1093/nar/22.1.11

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 11764287

Title: Photobiologic and photoimmunologic characteristics of XPA gene-deficient mice.

PubMed ID: 11764287

DOI: 10.1046/j.0022-202x.2001.00019.x

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 20304803

Title: Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase.

PubMed ID: 20304803

DOI: 10.1073/pnas.0915085107

PubMed ID: 32142649

Title: Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.

PubMed ID: 32142649

DOI: 10.1016/j.cell.2020.02.010

Sequence Information:

Length: 272
Mass: 31398
Checksum: 9061C9528F9E63CB
Sequence:

MATAEEKQTS PEPVAADEPA QLPAAVRASV ERKRQRALML RQARLAARPY PAAAATGGVA 
SVKAAPKMID TKGGFILEEE EEKHEIGNIV HEPGPVMEFD YTICEECGKE FMDSYLMNHF 
DLPTCDSCRD ADDKHKLITK TEAKQEYLLK DCDLEKREPA LRFLVKKNPR HSQWGDMKLY 
LKLQVVKRAL EVWGSQEALE DAKEVRQENR EKMKQKKFDK KVKELRRAIR SSVWKRETTT 
HQHKYGPEEN LEDDMYRKTC TLCGHELTYE KM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Xpa

Associated with

Other Information

Cloning and characterization of the mouse XPAC gene. PubMed ID: 8127648

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Photobiologic and photoimmunologic characteristics of XPA gene-deficient mice. PubMed ID: 11764287

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase. PubMed ID: 20304803

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair. PubMed ID: 32142649