Genular: Defining Cellular Identity and Function

Details for: Xpc

Gene ID: 22591

Symbol: Xpc

Ensembl ID: ENSMUSG00000030094

Description: xeroderma pigmentosum, complementation group C

Associated with

Dna damage recognition in gg-ner
(R-MMU-5696394)
Formation of incision complex in gg-ner
(R-MMU-5696395)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Metabolism of proteins
(R-MMU-392499)
Nucleotide excision repair
(R-MMU-5696398)
Post-translational protein modification
(R-MMU-597592)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Chromosome
(GO:0005694)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Damaged dna binding
(GO:0003684)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna damage sensor activity
(GO:0140612)
Dna repair
(GO:0006281)
Intracellular membrane-bounded organelle
(GO:0043231)
Mismatch repair
(GO:0006298)
Mitochondrion
(GO:0005739)
Mitotic intra-s dna damage checkpoint signaling
(GO:0031573)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleotide-excision repair
(GO:0006289)
Nucleotide-excision repair complex
(GO:0000109)
Nucleotide-excision repair factor 2 complex
(GO:0000111)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of dna-templated transcription
(GO:0045893)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Pyrimidine dimer repair by nucleotide-excision repair
(GO:0000720)
Regulation of mitotic cell cycle phase transition
(GO:1901990)
Response to uv-b
(GO:0010224)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Single-stranded dna binding
(GO:0003697)
Site of dna damage
(GO:0090734)
Transcription coactivator activity
(GO:0003713)
Uv-damage excision repair
(GO:0070914)
Xpc complex
(GO:0071942)

Other Information

Proteins

DNA repair protein complementing XP-C cells homolog

Genular Protein ID: 478093273

Symbol: XPC_MOUSE

Name: DNA repair protein complementing XP-C cells homolog

UniProtKB Accession Codes:

P51612 P54732 Q3TKI2 Q920M1 Q9DBW7

Database IDs:

Citations:

PubMed ID: 8604333

Title: Sequence of the mouse XPC cDNA and genomic structure of the human XPC gene.

PubMed ID: 8604333

DOI: 10.1093/nar/24.6.1026

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 7675084

Title: High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC.

PubMed ID: 7675084

DOI: 10.1038/377162a0

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 930
Mass: 104522
Checksum: 0C469AB21B4E4EE9
Sequence:

MAPKRTADGR RRKRGQKTED NKVARHEESV ADDFEDEKQK PRRKSSFPKV SQGKRKRGCS 
DPGDPTNGAA KKKVAKATAK SKNLKVLKEE ALSDGDDFRD SPADCKKAKK HPKSKVVDQG 
TDEDDSEDDW EEVEELTEPV LDMGENSATS PSDMPVKAVE IEIETPQQAK ERERSEKIKM 
EFETYLRRMM KRFNKEVQEN MHKVHLLCLL ASGFYRNSIC RQPDLLAIGL SIIPIRFTKV 
PLQDRDAYYL SNLVKWFIGT FTVNADLSAS EQDDLQTTLE RRIAIYSARD NEELVHIFLL 
ILRALQLLTR LVLSLQPIPL KSAVTKGRKS SKETSVEGPG GSSELSSNSP ESHNKPTTSR 
RIKEEETLSE GRGKATARGK RGTGTAGSRQ RRKPSCSEGE EAEQKVQGRP HARKRRVAAK 
VSYKEESESD GAGSGSDFEP SSGEGQHSSD EDCEPGPRKQ KRASAPQRTK AGSKSASKTQ 
RGSQCEPSSF PEASSSSSGC KRGKKVSSGA EEMADRKPAG VDQWLEVYCE PQAKWVCVDC 
VHGVVGQPVA CYKYATKPMT YVVGIDSDGW VRDVTQRYDP AWMTATRKCR VDAEWWAETL 
RPYRSLLTER EKKEDQEFQA KHLDQPLPTS ISTYKNHPLY ALKRHLLKFQ AIYPETAAVL 
GYCRGEAVYS RDCVHTLHSR DTWLKQARVV RLGEVPYKMV KGFSNRARKA RLSEPQLHDH 
NDLGLYGHWQ TEEYQPPIAV DGKVPRNEFG NVYLFLPSMM PVGCVQMTLP NLNRVARKLG 
IDCVQAITGF DFHGGYCHPV TDGYIVCEEF RDVLLAAWEN EQAIIEKKEK EKKEKRALGN 
WKLLVRGLLI RERLKLRYGA KSEAAAPHAA GGGLSSDEEE GTSSQAEAAR VLAASWPQNR 
EDPEQKSEYT KMTRKRRAAE ASHLFPFEKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Xpc

Associated with

Other Information

Sequence of the mouse XPC cDNA and genomic structure of the human XPC gene. PubMed ID: 8604333

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC. PubMed ID: 7675084

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319