Genular: Defining Cellular Identity and Function

Details for: Ywhah

Gene ID: 22629

Symbol: Ywhah

Ensembl ID: ENSMUSG00000018965

Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

Associated with

Activation of bad and translocation to mitochondria
(R-MMU-111447)
Activation of bh3-only proteins
(R-MMU-114452)
Apoptosis
(R-MMU-109581)
Cell cycle
(R-MMU-1640170)
Cell cycle checkpoints
(R-MMU-69620)
Chk1/chk2(cds1) mediated inactivation of cyclin b:cdk1 complex
(R-MMU-75035)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Intrinsic pathway for apoptosis
(R-MMU-109606)
Programmed cell death
(R-MMU-5357801)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate pkns
(R-MMU-5625740)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Actin binding
(GO:0003779)
Cerebellar granule cell to purkinje cell synapse
(GO:0150048)
Cytoplasm
(GO:0005737)
Cytoskeleton organization
(GO:0007010)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
Glucocorticoid catabolic process
(GO:0006713)
Glucocorticoid receptor signaling pathway
(GO:0042921)
Glutamatergic synapse
(GO:0098978)
Identical protein binding
(GO:0042802)
Intercalated disc
(GO:0014704)
Intracellular protein transport
(GO:0006886)
Membrane depolarization during action potential
(GO:0086010)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dendrite morphogenesis
(GO:0050774)
Nuclear glucocorticoid receptor binding
(GO:0035259)
Plasma membrane
(GO:0005886)
Positive regulation of dna-templated transcription
(GO:0045893)
Presynapse
(GO:0098793)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein heterodimerization activity
(GO:0046982)
Regulation of mitotic nuclear division
(GO:0007088)
Regulation of sodium ion transmembrane transporter activity
(GO:2000649)
Regulation of sodium ion transport
(GO:0002028)
Signal transduction
(GO:0007165)
Sodium channel regulator activity
(GO:0017080)
Synapse
(GO:0045202)
Transmembrane transporter binding
(GO:0044325)

Other Information

Proteins

14-3-3 protein eta

Genular Protein ID: 3405410641

Symbol: 1433F_MOUSE

Name: 14-3-3 protein eta

UniProtKB Accession Codes:

P68510 P11576 P70198 Q3TGZ9

Database IDs:

Citations:

PubMed ID: 9197417

Title: The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins.

PubMed ID: 9197417

DOI: 10.1007/s004380050453

PubMed ID: 9738002

Title: Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins.

PubMed ID: 9738002

DOI: 10.1074/jbc.273.39.25356

PubMed ID: 12008017

Title: Isolation and structure of the mouse 14-3-3 eta chain gene and the distribution of 14-3-3 eta mRNA in the mouse brain.

PubMed ID: 12008017

DOI: 10.1016/s0169-328x(02)00129-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9705322

Title: A novel sphingosine-dependent protein kinase (SDK1) specifically phosphorylates certain isoforms of 14-3-3 protein.

PubMed ID: 9705322

DOI: 10.1074/jbc.273.34.21834

PubMed ID: 11533041

Title: Identification of a novel interaction of 14-3-3 with p190RhoGEF.

PubMed ID: 11533041

DOI: 10.1074/jbc.m107709200

PubMed ID: 18397886

Title: Phosphorylation-dependent binding of 14-3-3 proteins controls TRESK regulation.

PubMed ID: 18397886

DOI: 10.1074/jbc.m800712200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20478393

Title: SLy2 targets the nuclear SAP30/HDAC1 complex.

PubMed ID: 20478393

DOI: 10.1016/j.biocel.2010.05.004

PubMed ID: 26047703

Title: Suppression of death-associated protein kinase 2 by interaction with 14-3-3 proteins.

PubMed ID: 26047703

DOI: 10.1016/j.bbrc.2015.05.105

Sequence Information:

Length: 246
Mass: 28212
Checksum: C12F62B4ABA76DA3
Sequence:

MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW 
RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LALLDKFLIK NCNDFQYESK 
VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEHMQPTHP IRLGLALNFS 
VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE 
EAGEGN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ywhah

Associated with

Other Information

The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins. PubMed ID: 9197417

Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins. PubMed ID: 9738002

Isolation and structure of the mouse 14-3-3 eta chain gene and the distribution of 14-3-3 eta mRNA in the mouse brain. PubMed ID: 12008017

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A novel sphingosine-dependent protein kinase (SDK1) specifically phosphorylates certain isoforms of 14-3-3 protein. PubMed ID: 9705322

Identification of a novel interaction of 14-3-3 with p190RhoGEF. PubMed ID: 11533041

Phosphorylation-dependent binding of 14-3-3 proteins controls TRESK regulation. PubMed ID: 18397886

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SLy2 targets the nuclear SAP30/HDAC1 complex. PubMed ID: 20478393

Suppression of death-associated protein kinase 2 by interaction with 14-3-3 proteins. PubMed ID: 26047703