Genular: Defining Cellular Identity and Function

Details for: Zpr1

Gene ID: 22687

Symbol: Zpr1

Ensembl ID: ENSMUSG00000032078

Description: ZPR1 zinc finger

Associated with

Apoptotic process involved in development
(GO:1902742)
Axon
(GO:0030424)
Axon development
(GO:0061564)
Cajal body
(GO:0015030)
Cajal body organization
(GO:0030576)
Cell differentiation
(GO:0030154)
Cell projection
(GO:0042995)
Cellular response to epidermal growth factor stimulus
(GO:0071364)
Cytoplasm
(GO:0005737)
Dna endoreduplication
(GO:0042023)
Dna replication
(GO:0006260)
Gemini of coiled bodies
(GO:0097504)
Growth cone
(GO:0030426)
Inner cell mass cell proliferation
(GO:0001833)
Metal ion binding
(GO:0046872)
Microtubule cytoskeleton organization
(GO:0000226)
Mrna processing
(GO:0006397)
Multicellular organism development
(GO:0007275)
Negative regulation of motor neuron apoptotic process
(GO:2000672)
Neuronal cell body
(GO:0043025)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Perikaryon
(GO:0043204)
Positive regulation of cell cycle
(GO:0045787)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of growth
(GO:0045927)
Positive regulation of protein import into nucleus
(GO:0042307)
Positive regulation of rna splicing
(GO:0033120)
Pre-mrna catabolic process
(GO:1990261)
Protein binding
(GO:0005515)
Receptor tyrosine kinase binding
(GO:0030971)
Regulation of myelination
(GO:0031641)
Rna splicing
(GO:0008380)
Spinal cord development
(GO:0021510)
Translation initiation factor binding
(GO:0031369)
Trophectodermal cell proliferation
(GO:0001834)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Zinc finger protein ZPR1

Genular Protein ID: 3048781462

Symbol: ZPR1_MOUSE

Name: Zinc finger protein ZPR1

UniProtKB Accession Codes:

Q62384

Database IDs:

Citations:

PubMed ID: 8650580

Title: Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.

PubMed ID: 8650580

DOI: 10.1126/science.272.5269.1797

PubMed ID: 9852145

Title: Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.

PubMed ID: 9852145

DOI: 10.1083/jcb.143.6.1471

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9763455

Title: The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells.

PubMed ID: 9763455

DOI: 10.1091/mbc.9.10.2963

PubMed ID: 15767679

Title: ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.

PubMed ID: 15767679

DOI: 10.1128/mcb.25.7.2744-2756.2005

PubMed ID: 16465397

Title: Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet.

PubMed ID: 16465397

PubMed ID: 16648254

Title: Deficiency of the zinc finger protein ZPR1 causes neurodegeneration.

PubMed ID: 16648254

DOI: 10.1073/pnas.0602057103

PubMed ID: 19966453

Title: Generation of a zinc finger protein ZPR1 mutant that constitutively interacted with translation elongation factor 1alpha.

PubMed ID: 19966453

DOI: 10.1271/bbb.90745

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22422766

Title: The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy.

PubMed ID: 22422766

DOI: 10.1093/hmg/dds102

PubMed ID: 17704259

Title: Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes.

PubMed ID: 17704259

DOI: 10.1073/pnas.0704915104

Sequence Information:

Length: 459
Mass: 50715
Checksum: 771D38C7B806044F
Sequence:

MSASGAVQPG HPGAAVGPSP AAAASPATGP LFRPLSAEDE EQQPTEIESL CMNCYRNGTT 
RLLLTKIPFF REIIVSSFSC EHCGWNNTEI QSAGRIQDQG VRYTLTVRSQ EDMNREVVKT 
DSATTRIPEL DFEIPAFSQK GALTTVEGLI SRAISGLEQD QPTRRAVEGA IAERIDEFIG 
KLKDLKQMAS PFTLVIDDPS GNSFVENPHA PQKDNALVIT YYDRTPQQAE MLGLQAEAPE 
EKAEEEDLRN EVLQFNTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS 
GGAVEPLGTR ITLHITDPSD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD 
IRELVTKNPF TLGDSSNPDQ SEKLQEFSQK LGQIIEGKMK AHFIMNDPAG NSYLQNVYAP 
EDDPEMKVER YKRTFDQNEE LGLNDMKTEG YEAGLAPQR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Zpr1

Associated with

Other Information

Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor. PubMed ID: 8650580

Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells. PubMed ID: 9852145

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells. PubMed ID: 9763455

ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies. PubMed ID: 15767679

Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet. PubMed ID: 16465397

Deficiency of the zinc finger protein ZPR1 causes neurodegeneration. PubMed ID: 16648254

Generation of a zinc finger protein ZPR1 mutant that constitutively interacted with translation elongation factor 1alpha. PubMed ID: 19966453

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy. PubMed ID: 22422766

Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes. PubMed ID: 17704259