Genular: Defining Cellular Identity and Function

Details for: Zic3

Gene ID: 22773

Symbol: Zic3

Ensembl ID: ENSMUSG00000067860

Description: zinc finger protein of the cerebellum 3

Associated with

Anterior/posterior pattern specification
(GO:0009952)
Atrial cardiac muscle tissue development
(GO:0003228)
Axial mesoderm development
(GO:0048318)
Cell cycle
(GO:0007049)
Cell differentiation
(GO:0030154)
Central nervous system development
(GO:0007417)
Central nervous system segmentation
(GO:0035283)
Cranial skeletal system development
(GO:1904888)
Cytoplasm
(GO:0005737)
Determination of digestive tract left/right asymmetry
(GO:0071907)
Determination of left/right asymmetry in nervous system
(GO:0035545)
Determination of left/right symmetry
(GO:0007368)
Determination of liver left/right asymmetry
(GO:0071910)
Determination of pancreatic left/right asymmetry
(GO:0035469)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Embryonic pattern specification
(GO:0009880)
Face development
(GO:0060324)
Forebrain development
(GO:0030900)
Gastrulation
(GO:0007369)
Gene expression
(GO:0010467)
Germ-line stem cell population maintenance
(GO:0030718)
Heart development
(GO:0007507)
Heart looping
(GO:0001947)
Hippocampus development
(GO:0021766)
Left/right axis specification
(GO:0070986)
Left/right pattern formation
(GO:0060972)
Limb morphogenesis
(GO:0035108)
Lung development
(GO:0030324)
Maintenance of cell number
(GO:0098727)
Mesoderm development
(GO:0007498)
Metal ion binding
(GO:0046872)
Mrna transcription by rna polymerase ii
(GO:0042789)
Multicellular organism development
(GO:0007275)
Nervous system development
(GO:0007399)
Neural plate development
(GO:0001840)
Neuron differentiation
(GO:0030182)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Olfactory bulb development
(GO:0021772)
Outer ear morphogenesis
(GO:0042473)
Paraxial mesoderm development
(GO:0048339)
Pattern specification process
(GO:0007389)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Primitive streak formation
(GO:0090009)
Protein binding
(GO:0005515)
Regulation of dna-binding transcription factor activity
(GO:0051090)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Skeletal system development
(GO:0001501)
Smoothened signaling pathway
(GO:0007224)
Stem cell differentiation
(GO:0048863)
Stem cell population maintenance
(GO:0019827)
Transcription coactivator activity
(GO:0003713)

Other Information

Proteins

Zinc finger protein ZIC 3

Genular Protein ID: 3963154869

Symbol: ZIC3_MOUSE

Name: Zinc finger protein ZIC 3

UniProtKB Accession Codes:

Q62521 A2AWK3 Q3UYV1 Q8BSB3

Database IDs:

Citations:

PubMed ID: 8557628

Title: The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired.

PubMed ID: 8557628

DOI: 10.1074/jbc.271.2.1043

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 11053430

Title: Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins.

PubMed ID: 11053430

DOI: 10.1074/jbc.m004430200

PubMed ID: 11238441

Title: Physical and functional interactions between Zic and Gli proteins.

PubMed ID: 11238441

DOI: 10.1074/jbc.c000773200

PubMed ID: 11959836

Title: A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice.

PubMed ID: 11959836

DOI: 10.1242/dev.129.9.2293

PubMed ID: 15207726

Title: Myogenic repressor I-mfa interferes with the function of Zic family proteins.

PubMed ID: 15207726

DOI: 10.1016/j.bbrc.2004.05.158

PubMed ID: 21858219

Title: Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease.

PubMed ID: 21858219

DOI: 10.1371/journal.pone.0023755

Sequence Information:

Length: 466
Mass: 50446
Checksum: C92C06EC06DF601A
Sequence:

MTMLLDGGPQ FPGLGVGSFG APRHHEMPNR EPAGMGLNPF GDSTHAAAAA AAAAAFKLSP 
ATAHDLSSGQ SSAFTPQGSG YANALGHHHH HHHHHHASQV PTYGGAASAA FNSTRDFLFR 
QRGSGLSEAA SGGGQHGLFA GSASSLHAPA GIPEPPSYLL FPGLHEQGAG HPSPTGHVDN 
NQVHLGLRGE LFGRADPYRP VASPRTDPYA ASAQFPNYSP MNMNMGVNVA AHHGPGAFFR 
YMRQPIKQEL SCKWIEEAQL SRPKKSCDRT FSTMHELVTH VTMEHVGGPE QNNHVCYWEE 
CPREGKSFKA KYKLVNHIRV HTGEKPFPCP FPGCGKIFAR SENLKIHKRT HTGEKPFKCE 
FEGCDRRFAN SSDRKKHMHV HTSDKPYICK VCDKSYTHPS SLRKHMKVHE SQGSDSSPAA 
SSGYESSTPP AIASANSKDT TKTPSAVQTS TSHNPGLPPN FNEWYV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Zic3

Associated with

Other Information

The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired. PubMed ID: 8557628

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. PubMed ID: 11053430

Physical and functional interactions between Zic and Gli proteins. PubMed ID: 11238441

A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. PubMed ID: 11959836

Myogenic repressor I-mfa interferes with the function of Zic family proteins. PubMed ID: 15207726

Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease. PubMed ID: 21858219