Genular: Defining Cellular Identity and Function

Details for: Zp3

Gene ID: 22788

Symbol: Zp3

Ensembl ID: ENSMUSG00000004948

Description: zona pellucida glycoprotein 3

Associated with

Fertilization
(R-MMU-1187000)
Interaction with cumulus cells and the zona pellucida
(R-MMU-2534343)
Reproduction
(R-MMU-1474165)
Acrosin binding
(GO:0032190)
Binding of sperm to zona pellucida
(GO:0007339)
Blastocyst formation
(GO:0001825)
Carbohydrate binding
(GO:0030246)
Collagen-containing extracellular matrix
(GO:0062023)
Egg coat
(GO:0035805)
Egg coat formation
(GO:0035803)
Extracellular matrix
(GO:0031012)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Humoral immune response mediated by circulating immunoglobulin
(GO:0002455)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Negative regulation of binding of sperm to zona pellucida
(GO:2000360)
Negative regulation of dna-templated transcription
(GO:0045892)
Oocyte development
(GO:0048599)
Plasma membrane
(GO:0005886)
Positive regulation of acrosomal vesicle exocytosis
(GO:2000368)
Positive regulation of acrosome reaction
(GO:2000344)
Positive regulation of antral ovarian follicle growth
(GO:2000388)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of humoral immune response
(GO:0002922)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of interleukin-4 production
(GO:0032753)
Positive regulation of leukocyte migration
(GO:0002687)
Positive regulation of ovarian follicle development
(GO:2000386)
Positive regulation of t cell proliferation
(GO:0042102)
Positive regulation of type ii interferon production
(GO:0032729)
Positive regulation of type iv hypersensitivity
(GO:0001809)
Protein binding
(GO:0005515)
Receptor ligand activity
(GO:0048018)
Regulation of signaling receptor activity
(GO:0010469)
Structural constituent of egg coat
(GO:0035804)

Other Information

Proteins

Zona pellucida sperm-binding protein 3

Genular Protein ID: 3283773058

Symbol: ZP3_MOUSE

Name: Zona pellucida sperm-binding protein 3

UniProtKB Accession Codes:

P10761 Q4FZI2

Database IDs:

Citations:

PubMed ID: 3378665

Title: Molecular analysis of cDNA coding for ZP3, a sperm binding protein of the mouse zona pellucida.

PubMed ID: 3378665

DOI: 10.1016/0012-1606(88)90315-6

PubMed ID: 2541416

Title: Nucleotide sequence of the gene encoding zona pellucida glycoprotein ZP3 -- the mouse sperm receptor.

PubMed ID: 2541416

DOI: 10.1093/nar/17.7.2861

PubMed ID: 2842770

Title: Primary structure of the mouse sperm receptor polypeptide determined by genomic cloning.

PubMed ID: 2842770

DOI: 10.1073/pnas.85.17.6409

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1330788

Title: Identification of a region of mouse zona pellucida glycoprotein mZP3 that possesses sperm receptor activity.

PubMed ID: 1330788

DOI: 10.1016/0012-1606(92)90070-w

PubMed ID: 12799386

Title: Structural characterization of native mouse zona pellucida proteins using mass spectrometry.

PubMed ID: 12799386

DOI: 10.1074/jbc.m304026200

PubMed ID: 19052627

Title: Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats.

PubMed ID: 19052627

DOI: 10.1038/nature07599

Sequence Information:

Length: 424
Mass: 46304
Checksum: 9089903FBD268365
Sequence:

MASSYFLFLC LLLCGGPELC NSQTLWLLPG GTPTPVGSSS PVKVECLEAE LVVTVSRDLF 
GTGKLVQPGD LTLGSEGCQP RVSVDTDVVR FNAQLHECSS RVQMTKDALV YSTFLLHDPR 
PVSGLSILRT NRVEVPIECR YPRQGNVSSH PIQPTWVPFR ATVSSEEKLA FSLRLMEENW 
NTEKSAPTFH LGEVAHLQAE VQTGSHLPLQ LFVDHCVATP SPLPDPNSSP YHFIVDFHGC 
LVDGLSESFS AFQVPRPRPE TLQFTVDVFH FANSSRNTLY ITCHLKVAPA NQIPDKLNKA 
CSFNKTSQSW LPVEGDADIC DCCSHGNCSN SSSSQFQIHG PRQWSKLVSR NRRHVTDEAD 
VTVGPLIFLG KANDQTVEGW TASAQTSVAL GLGLATVAFL TLAAIVLAVT RKCHSSSYLV 
SLPQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Zp3

Associated with

Other Information

Molecular analysis of cDNA coding for ZP3, a sperm binding protein of the mouse zona pellucida. PubMed ID: 3378665

Nucleotide sequence of the gene encoding zona pellucida glycoprotein ZP3 -- the mouse sperm receptor. PubMed ID: 2541416

Primary structure of the mouse sperm receptor polypeptide determined by genomic cloning. PubMed ID: 2842770

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a region of mouse zona pellucida glycoprotein mZP3 that possesses sperm receptor activity. PubMed ID: 1330788

Structural characterization of native mouse zona pellucida proteins using mass spectrometry. PubMed ID: 12799386

Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats. PubMed ID: 19052627