Details for: CASC3
Associated with
Other Information
Genular Protein ID: 458796852
Symbol: CASC3_HUMAN
Name: Protein CASC3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7490069
Title: Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.
PubMed ID: 7490069
PubMed ID: 12080473
Title: Metastatic lymph node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer.
PubMed ID: 12080473
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11980659
Title: Targets of gene amplification and overexpression at 17q in gastric cancer.
PubMed ID: 11980659
PubMed ID: 15166247
Title: Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module.
PubMed ID: 15166247
PubMed ID: 16170325
Title: The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.
PubMed ID: 16170325
DOI: 10.1038/nsmb990
PubMed ID: 16314458
Title: Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.
PubMed ID: 16314458
DOI: 10.1261/rna.2155905
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17652158
Title: The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly.
PubMed ID: 17652158
DOI: 10.1242/jcs.009225
PubMed ID: 17375189
Title: MLN51 stimulates the RNA-helicase activity of eIF4AIII.
PubMed ID: 17375189
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21478859
Title: RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.
PubMed ID: 21478859
DOI: 10.1038/ncb2222
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25220460
Title: The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.
PubMed ID: 25220460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 16923391
Title: The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA.
PubMed ID: 16923391
PubMed ID: 16931718
Title: Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
PubMed ID: 16931718
PubMed ID: 19033377
Title: Mechanism of ATP turnover inhibition in the EJC.
PubMed ID: 19033377
DOI: 10.1261/rna.1283109
PubMed ID: 20479275
Title: Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.
PubMed ID: 20479275
PubMed ID: 28502770
Title: An Atomic Structure of the Human Spliceosome.
PubMed ID: 28502770
PubMed ID: 29301961
Title: Structure of a human catalytic step I spliceosome.
PubMed ID: 29301961
Sequence Information:
- Length: 703
- Mass: 76278
- Checksum: 642A4C01C8DD3BE0
- Sequence:
MADRRRQRAS QDTEDEESGA SGSDSGGSPL RGGGSCSGSA GGGGSGSLPS QRGGRTGALH LRRVESGGAK SAEESECESE DGIEGDAVLS DYESAEDSEG EEGEYSEEEN SKVELKSEAN DAVNSSTKEE KGEEKPDTKS TVTGERQSGD GQESTEPVEN KVGKKGPKHL DDDEDRKNPA YIPRKGLFFE HDLRGQTQEE EVRPKGRQRK LWKDEGRWEH DKFREDEQAP KSRQELIALY GYDIRSAHNP DDIKPRRIRK PRYGSPPQRD PNWNGERLNK SHRHQGLGGT LPPRTFINRN AAGTGRMSAP RNYSRSGGFK EGRAGFRPVE AGGQHGGRSG ETVKHEISYR SRRLEQTSVR DPSPEADAPV LGSPEKEEAA SEPPAAAPDA APPPPDRPIE KKSYSRARRT RTKVGDAVKL AEEVPPPPEG LIPAPPVPET TPTPPTKTGT WEAPVDSSTS GLEQDVAQLN IAEQNWSPGQ PSFLQPRELR GMPNHIHMGA GPPPQFNRME EMGVQGGRAK RYSSQRQRPV PEPPAPPVHI SIMEGHYYDP LQFQGPIYTH GDSPAPLPPQ GMLVQPGMNL PHPGLHPHQT PAPLPNPGLY PPPVSMSPGQ PPPQQLLAPT YFSAPGVMNF GNPSYPYAPG ALPPPPPPHL YPNTQAPSQV YGGVTYYNPA QQQVQPKPSP PRRTPQPVTI KPPPPEVVSR GSS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.