COG2 | ENSG00000135775 | NCBI 22796

Details for: COG2

Gene ID: 22796

Symbol: COG2

Ensembl ID: ENSG00000135775

Description: component of oligomeric golgi complex 2

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Copi-mediated anterograde transport
(R-HSA-6807878)
Er to golgi anterograde transport
(R-HSA-199977)
Intra-golgi and retrograde golgi-to-er traffic
(R-HSA-6811442)
Intra-golgi traffic
(R-HSA-6811438)
Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Retrograde transport at the trans-golgi-network
(R-HSA-6811440)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Vesicle-mediated transport
(R-HSA-5653656)
Glycosylation
(GO:0070085)
Golgi membrane
(GO:0000139)
Golgi organization
(GO:0007030)
Golgi stack
(GO:0005795)
Golgi transport complex
(GO:0017119)
Intra-golgi vesicle-mediated transport
(GO:0006891)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Retrograde transport, vesicle recycling within golgi
(GO:0000301)
Trans-golgi network membrane
(GO:0032588)

Other Information

Proteins

Conserved oligomeric Golgi complex subunit 2

Genular Protein ID: 2895277267

Symbol: COG2_HUMAN

Name: Conserved oligomeric Golgi complex subunit 2

UniProtKB Accession Codes:

Q14746 Q86U99

Database IDs:

Citations:

PubMed ID: 7962052

Title: LDLC encodes a brefeldin A-sensitive, peripheral Golgi protein required for normal Golgi function.

PubMed ID: 7962052

DOI: 10.1083/jcb.127.3.679

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24784932

Title: Mutations in COG2 encoding a subunit of the conserved oligomeric golgi complex cause a congenital disorder of glycosylation.

PubMed ID: 24784932

DOI: 10.1111/cge.12417

Sequence Information:

Length: 738
Mass: 83208
Checksum: 8E393CBE1114DB28
Sequence:

MEKSRMNLPK GPDTLCFDKD EFMKEDFDVD HFVSDCRKRV QLEELRDDLE LYYKLLKTAM 
VELINKDYAD FVNLSTNLVG MDKALNQLSV PLGQLREEVL SLRSSVSEGI RAVDERMSKQ 
EDIRKKKMCV LRLIQVIRSV EKIEKILNSQ SSKETSALEA SSPLLTGQIL ERIATEFNQL 
QFHAVQSKGM PLLDKVRPRI AGITAMLQQS LEGLLLEGLQ TSDVDIIRHC LRTYATIDKT 
RDAEALVGQV LVKPYIDEVI IEQFVESHPN GLQVMYNKLL EFVPHHCRLL REVTGGAISS 
EKGNTVPGYD FLVNSVWPQI VQGLEEKLPS LFNPGNPDAF HEKYTISMDF VRRLERQCGS 
QASVKRLRAH PAYHSFNKKW NLPVYFQIRF REIAGSLEAA LTDVLEDAPA ESPYCLLASH 
RTWSSLRRCW SDEMFLPLLV HRLWRLTLQI LARYSVFVNE LSLRPISNES PKEIKKPLVT 
GSKEPSITQG NTEDQGSGPS ETKPVVSISR TQLVYVVADL DKLQEQLPEL LEIIKPKLEM 
IGFKNFSSIS AALEDSQSSF SACVPSLSSK IIQDLSDSCF GFLKSALEVP RLYRRTNKEV 
PTTASSYVDS ALKPLFQLQS GHKDKLKQAI IQQWLEGTLS ESTHKYYETV SDVLNSVKKM 
EESLKRLKQA RKTTPANPVG PSGGMSDDDK IRLQLALDVE YLGEQIQKLG LQASDIKSFS 
ALAELVAAAK DQATAEQP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: COG2

Associated with

Other Information

LDLC encodes a brefeldin A-sensitive, peripheral Golgi protein required for normal Golgi function. PubMed ID: 7962052

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334