Details for: RRAS2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 4.47
Marker Score: 59,437 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 2.54
Marker Score: 2,268 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 2.3
Marker Score: 1,119 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 2.12
Marker Score: 1,700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.68
Marker Score: 25,078 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.67
Marker Score: 1,761 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.67
Marker Score: 15,708 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.6
Marker Score: 6,191 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.59
Marker Score: 3,875 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.53
Marker Score: 2,576 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.53
Marker Score: 4,222 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.51
Marker Score: 57,163 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,185 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.45
Marker Score: 11,078 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.43
Marker Score: 12,295 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.4
Marker Score: 2,162 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.39
Marker Score: 1,737 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.39
Marker Score: 405 - Cell Name: germinal center B cell (CL0000844)
Fold Change: 1.38
Marker Score: 841 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.38
Marker Score: 4,899 - Cell Name: fat cell (CL0000136)
Fold Change: 1.38
Marker Score: 770 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.34
Marker Score: 1,319 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.33
Marker Score: 1,473 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.33
Marker Score: 81,885 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.24
Marker Score: 1,299 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.24
Marker Score: 977 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 1.21
Marker Score: 388 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.2
Marker Score: 3,569 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.2
Marker Score: 18,800 - Cell Name: oocyte (CL0000023)
Fold Change: 1.2
Marker Score: 296 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.19
Marker Score: 11,348 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.19
Marker Score: 4,983 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.16
Marker Score: 25,974 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.16
Marker Score: 676 - Cell Name: pneumocyte (CL0000322)
Fold Change: 1.15
Marker Score: 1,844 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 1.14
Marker Score: 762 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.08
Marker Score: 2,545 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 1.08
Marker Score: 2,258 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.07
Marker Score: 597 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.07
Marker Score: 1,149 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.05
Marker Score: 700 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.03
Marker Score: 373 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.02
Marker Score: 20,363 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 1.02
Marker Score: 1,773 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 1.01
Marker Score: 359 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.01
Marker Score: 1,353 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.01
Marker Score: 604 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1
Marker Score: 1,926 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.99
Marker Score: 372 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.99
Marker Score: 3,518 - Cell Name: centroblast (CL0009112)
Fold Change: 0.99
Marker Score: 486 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,397 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.98
Marker Score: 590 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.98
Marker Score: 1,014 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 0.96
Marker Score: 240 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.96
Marker Score: 240 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,400 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.94
Marker Score: 549 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.94
Marker Score: 4,594 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 481 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 439 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.91
Marker Score: 3,525 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.91
Marker Score: 334 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.91
Marker Score: 5,870 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.91
Marker Score: 31,612 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.91
Marker Score: 3,935 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.91
Marker Score: 240 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.91
Marker Score: 1,143 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,710 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.9
Marker Score: 337 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.9
Marker Score: 305 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.9
Marker Score: 2,242 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.89
Marker Score: 522 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.89
Marker Score: 3,507 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 0.89
Marker Score: 369 - Cell Name: podocyte (CL0000653)
Fold Change: 0.88
Marker Score: 326 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.88
Marker Score: 253 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.87
Marker Score: 933 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.87
Marker Score: 207 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 311 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.86
Marker Score: 764 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.86
Marker Score: 29,103 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,880 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.85
Marker Score: 1,029 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.84
Marker Score: 1,364 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.84
Marker Score: 713 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 0.84
Marker Score: 284 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.84
Marker Score: 582 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.83
Marker Score: 240 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.83
Marker Score: 357 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.82
Marker Score: 452 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.82
Marker Score: 1,862 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.82
Marker Score: 314 - Cell Name: B-1b B cell (CL0000821)
Fold Change: 0.81
Marker Score: 187 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.81
Marker Score: 5,289 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.81
Marker Score: 257 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 0.81
Marker Score: 689 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.8
Marker Score: 280 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.8
Marker Score: 1,150
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1895638431
Symbol: RRAS2_HUMAN
Name: Ras-related protein R-Ras2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2108320
Title: Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.
PubMed ID: 2108320
PubMed ID: 8052619
Title: A human oncogene of the RAS superfamily unmasked by expression cDNA cloning.
PubMed ID: 8052619
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15308774
Title: A tagging-via-substrate technology for detection and proteomics of farnesylated proteins.
PubMed ID: 15308774
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 31130282
Title: Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome.
PubMed ID: 31130282
PubMed ID: 31130285
Title: Germline-Activating RRAS2 Mutations Cause Noonan Syndrome.
PubMed ID: 31130285
PubMed ID: 28406396
Title: SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation.
PubMed ID: 28406396
DOI: 10.7554/elife.25158
Sequence Information:
- Length: 204
- Mass: 23400
- Checksum: BA7D4759DC49446F
- Sequence:
MAAAGWRDGS GQEKYRLVVV GGGGVGKSAL TIQFIQSYFV TDYDPTIEDS YTKQCVIDDR AARLDILDTA GQEEFGAMRE QYMRTGEGFL LVFSVTDRGS FEEIYKFQRQ ILRVKDRDEF PMILIGNKAD LDHQRQVTQE EGQQLARQLK VTYMEASAKI RMNVDQAFHE LVRVIRKFQE QECPPSPEPT RKEKDKKGCH CVIF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.