Details for: IKZF3

Gene ID: 22806

Symbol: IKZF3

Ensembl ID: ENSG00000161405

Description: IKAROS family zinc finger 3

Associated with

Other Information

Genular Protein ID: 2819638871

Symbol: IKZF3_HUMAN

Name: Zinc finger protein Aiolos

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10552935

Title: Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping.

PubMed ID: 10552935

DOI: 10.1006/geno.1999.5949

PubMed ID: 11745366

Title: Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene.

PubMed ID: 11745366

DOI: 10.1002/1521-4141(200112)31:12<3469::aid-immu3469>3.0.co;2-g

PubMed ID: 17646674

Title: Combinatorial effects of splice variants modulate function of Aiolos.

PubMed ID: 17646674

DOI: 10.1242/jcs.007344

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10369681

Title: Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization.

PubMed ID: 10369681

DOI: 10.1093/emboj/18.12.3419

PubMed ID: 10978333

Title: Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

PubMed ID: 10978333

DOI: 10.1074/jbc.m005457200

PubMed ID: 11714801

Title: The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis.

PubMed ID: 11714801

DOI: 10.4049/jimmunol.167.11.6366

PubMed ID: 20676092

Title: Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells.

PubMed ID: 20676092

DOI: 10.1038/ni.1915

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 34155405

Title: A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS.

PubMed ID: 34155405

DOI: 10.1038/s41590-021-00951-z

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

Sequence Information:

  • Length: 509
  • Mass: 58023
  • Checksum: D1BB4A0A9A71B81A
  • Sequence:
  • MEDIQTNAEL KSTQEQSVPA ESAAVLNDYS LTKSHEMENV DSGEGPANED EDIGDDSMKV 
    KDEYSERDEN VLKSEPMGNA EEPEIPYSYS REYNEYENIK LERHVVSFDS SRPTSGKMNC 
    DVCGLSCISF NVLMVHKRSH TGERPFQCNQ CGASFTQKGN LLRHIKLHTG EKPFKCHLCN 
    YACQRRDALT GHLRTHSVEK PYKCEFCGRS YKQRSSLEEH KERCRTFLQS TDPGDTASAE 
    ARHIKAEMGS ERALVLDRLA SNVAKRKSSM PQKFIGEKRH CFDVNYNSSY MYEKESELIQ 
    TRMMDQAINN AISYLGAEAL RPLVQTPPAP TSEMVPVISS MYPIALTRAE MSNGAPQELE 
    KKSIHLPEKS VPSERGLSPN NSGHDSTDTD SNHEERQNHI YQQNHMVLSR ARNGMPLLKE 
    VPRSYELLKP PPICPRDSVK VINKEGEVMD VYRCDHCRVL FLDYVMFTIH MGCHGFRDPF 
    ECNMCGYRSH DRYEFSSHIA RGEHRALLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.