PHLDA1 | ENSG00000139289 | NCBI 22822

Details for: PHLDA1

Gene ID: 22822

Symbol: PHLDA1

Ensembl ID: ENSG00000139289

Description: pleckstrin homology like domain family A member 1

Associated with

Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
G2/m transition
(R-HSA-69275)
Interaction between phlda1 and aurka
(R-HSA-8854521)
Mitotic g2-g2/m phases
(R-HSA-453274)
Apoptotic process
(GO:0006915)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Fasl biosynthetic process
(GO:0045210)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Phosphatidylinositol phosphate binding
(GO:1901981)
Positive regulation of apoptotic process
(GO:0043065)
Protein binding
(GO:0005515)

Other Information

Proteins

Pleckstrin homology-like domain family A member 1

Genular Protein ID: 2929198017

Symbol: PHLA1_HUMAN

Name: Pleckstrin homology-like domain family A member 1

UniProtKB Accession Codes:

Q8WV24 A1A4G9 Q15184 Q2TAN2 Q9NZ17

Database IDs:

Citations:

PubMed ID: 10894922

Title: Assignment of the human PHLDA1 gene to chromosome 12q15 by radiation hybrid mapping.

PubMed ID: 10894922

DOI: 10.1159/000015575

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12384558

Title: Identification of the human PHLDA1/TDAG51 gene: down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation.

PubMed ID: 12384558

PubMed ID: 11369516

Title: Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product.

PubMed ID: 11369516

DOI: 10.1016/s0898-6568(01)00141-3

PubMed ID: 12738777

Title: TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia.

PubMed ID: 12738777

DOI: 10.1074/jbc.m212897200

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

Length: 401
Mass: 45016
Checksum: 1E01E7F75116A517
Sequence:

MRRAPAAERL LELGFPPRCG RQEPPFPLGV TRGWGRWPIQ KRREGARPVP FSERSQEDGR 
GPAARSSGTL WRIRTRLSLC RDPEPPPPLC LLRVSLLCAL RAGGRGSRWG EDGARLLLLP 
PARAAGNGEA EPSGGPSYAG RMLESSGCKA LKEGVLEKRS DGLLQLWKKK CCILTEEGLL 
LIPPKQLQHQ QQQQQQQQQQ QQQQPGQGPA EPSQPSGPAV ASLEPPVKLK ELHFSNMKTV 
DCVERKGKYM YFTVVMAEGK EIDFRCPQDQ GWNAEITLQM VQYKNRQAIL AVKSTRQKQQ 
HLVQQQPPSQ PQPQPQLQPQ PQPQPQPQPQ PQSQPQPQPQ PKPQPQQLHP YPHPHPHPHS 
HPHSHPHPHP HPHPHQIPHP HPQPHSQPHG HRLLRSTSNS A

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PHLDA1

Associated with

Other Information

Assignment of the human PHLDA1 gene to chromosome 12q15 by radiation hybrid mapping. PubMed ID: 10894922

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of the human PHLDA1/TDAG51 gene: down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation. PubMed ID: 12384558

Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product. PubMed ID: 11369516

TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. PubMed ID: 12738777