Details for: VASH1

Gene ID: 22846

Symbol: VASH1

Ensembl ID: ENSG00000071246

Description: vasohibin 1

Associated with

Other Information

Genular Protein ID: 1328655528

Symbol: VASH1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7L8A9 Q96H02 Q9UBF4 Q9Y629

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 4 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 EMDB 1 Ensembl 2 ExpressionAtlas 1 GO 19 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 26 PDBsum 14 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 3 SAM 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15467828

Title: Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis.

PubMed ID: 15467828

DOI: 10.1172/jci21152

PubMed ID: 15649403

Title: Gene regulation of a novel angiogenesis inhibitor, vasohibin, in endothelial cells.

PubMed ID: 15649403

DOI: 10.1016/j.bbrc.2004.12.073

PubMed ID: 16488400

Title: Multiple processing forms and their biological activities of a novel angiogenesis inhibitor vasohibin.

PubMed ID: 16488400

DOI: 10.1016/j.bbrc.2006.01.185

PubMed ID: 16707096

Title: Vasohibin prevents arterial neointimal formation through angiogenesis inhibition.

PubMed ID: 16707096

DOI: 10.1016/j.bbrc.2006.04.176

PubMed ID: 19204325

Title: Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis.

PubMed ID: 19204325

DOI: 10.1182/blood-2008-07-170316

PubMed ID: 20736312

Title: Isolation of a small vasohibin-binding protein (SVBP) and its role in vasohibin secretion.

PubMed ID: 20736312

DOI: 10.1242/jcs.067538

PubMed ID: 26794318

Title: Vasohibins: new transglutaminase-like cysteine proteases possessing a non-canonical Cys-His-Ser catalytic triad.

PubMed ID: 26794318

DOI: 10.1093/bioinformatics/btv761

PubMed ID: 27879017

Title: Domain architecture of vasohibins required for their chaperone-dependent unconventional extracellular release.

PubMed ID: 27879017

DOI: 10.1002/pro.3089

PubMed ID: 29146869

Title: Vasohibins encode tubulin detyrosinating activity.

PubMed ID: 29146869

DOI: 10.1126/science.aao5676

PubMed ID: 31235911

Title: Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.

PubMed ID: 31235911

DOI: 10.1038/s41594-019-0241-y

PubMed ID: 31171830

Title: Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.

PubMed ID: 31171830

DOI: 10.1038/s41422-019-0187-y

PubMed ID: 31270470

Title: Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.

PubMed ID: 31270470

DOI: 10.1038/s41594-019-0254-6

PubMed ID: 31235910

Title: Structural basis of tubulin detyrosination by vasohibins.

PubMed ID: 31235910

DOI: 10.1038/s41594-019-0242-x

Sequence Information:

  • Length: 365
  • Mass: 40957
  • Checksum: CEE39875FA9DA70B
  • Sequence:
    • MPGGKKVAGG GSSGATPTSA AATAPSGVRR LETSEGTSAQ RDEEPEEEGE EDLRDGGVPF 
FVNRGGLPVD EATWERMWKH VAKIHPDGEK VAQRIRGATD LPKIPIPSVP TFQPSTPVPE 
RLEAVQRYIR ELQYNHTGTQ FFEIKKSRPL TGLMDLAKEM TKEALPIKCL EAVILGIYLT 
NSMPTLERFP ISFKTYFSGN YFRHIVLGVN FAGRYGALGM SRREDLMYKP PAFRTLSELV 
LDFEAAYGRC WHVLKKVKLG QSVSHDPHSV EQIEWKHSVL DVERLGRDDF RKELERHARD 
MRLKIGKGTG PPSPTKDRKK DVSSPQRAQS SPHRRNSRSE RRPSGDKKTS EPKAMPDLNG 
YQIRV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.