Details for: CILK1

Gene ID: 22858

Symbol: CILK1

Ensembl ID: ENSG00000112144

Description: ciliogenesis associated kinase 1

Associated with

Other Information

Genular Protein ID: 3466843383

Symbol: CILK1_HUMAN

Name: Serine/threonine-protein kinase ICK

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10699974

Title: Intestinal cell kinase (ICK) localizes to the crypt region and requires a dual phosphorylation site found in map kinases.

PubMed ID: 10699974

DOI: 10.1002/(sici)1097-4652(200004)183:1<129::aid-jcp15>3.0.co;2-s

PubMed ID: 12103360

Title: The identification and subcellular localization of human MRK.

PubMed ID: 12103360

DOI: 10.1016/s1389-0344(02)00002-3

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15988018

Title: Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase.

PubMed ID: 15988018

DOI: 10.1128/mcb.25.14.6047-6064.2005

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 24797473

Title: ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.

PubMed ID: 24797473

DOI: 10.1002/embj.201488175

PubMed ID: 24853502

Title: Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling.

PubMed ID: 24853502

DOI: 10.1073/pnas.1323161111

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 19185282

Title: A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems.

PubMed ID: 19185282

DOI: 10.1016/j.ajhg.2008.12.017

PubMed ID: 29539279

Title: Variant intestinal-cell kinase in juvenile myoclonic epilepsy.

PubMed ID: 29539279

DOI: 10.1056/nejmoa1700175

Sequence Information:

  • Length: 632
  • Mass: 71427
  • Checksum: F4C22C6CCD5878D2
  • Sequence:
  • MNRYTTIRQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 
    NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERNKLFPES AIRNIMYQIL QGLAFIHKHG 
    FFHRDLKPEN LLCMGPELVK IADFGLAREI RSKPPYTDYV STRWYRAPEV LLRSTNYSSP 
    IDVWAVGCIM AEVYTLRPLF PGASEIDTIF KICQVLGTPK KTDWPEGYQL SSAMNFRWPQ 
    CVPNNLKTLI PNASSEAVQL LRDMLQWDPK KRPTASQALR YPYFQVGHPL GSTTQNLQDS 
    EKPQKGILEK AGPPPYIKPV PPAQPPAKPH TRISSRQHQA SQPPLHLTYP YKAEVSRTDH 
    PSHLQEDKPS PLLFPSLHNK HPQSKITAGL EHKNGEIKPK SRRRWGLISR STKDSDDWAD 
    LDDLDFSPSL SRIDLKNKKR QSDDTLCRFE SVLDLKPSEP VGTGNSAPTQ TSYQRRDTPT 
    LRSAAKQHYL KHSRYLPGIS IRNGILSNPG KEFIPPNPWS SSGLSGKSSG TMSVISKVNS 
    VGSSSTSSSG LTGNYVPSFL KKEIGSAMQR VHLAPIPDPS PGYSSLKAMR PHPGRPFFHT 
    QPRSTPGLIP RPPAAQPVHG RTDWASKYAS RR

Genular Protein ID: 199869068

Symbol: B3KQG4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 632
  • Mass: 71455
  • Checksum: A61D861569C1BEC9
  • Sequence:
  • MNRYTTIRQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 
    NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERNKLFPES AIRNIMYQIL QGLAFIHKHG 
    FFHRDLKPEN LLCMGPELVK IADFGLAREI RSKPPYTDYV STRWYRAPEV LLRSTNYSSP 
    IDVWAVGCIM AEVYTLRPLF PGASEIDTIF KICQVLGTPK RTDWPEGYQL SSAMNFRWPQ 
    CVPNNLKTLI PNASSEAVQL LRDMLQWDPK KRPTASQALR YPYFQVGHPL GSTTQNLQDS 
    EKPQKGILEK AGPPPYIKPV PPAQPPAKPH TRISSRQHQA SQPPLHLTYP YKAEVSRTDH 
    PSHLQEDKPS PLLFPSLHNK HPQSKITAGL EHKNGEIKPK SRRRWGLISR STKDSDDWAD 
    LDDLDFSPSL SRIDLKNKKR QSDDTLCRFE SVLDLKPSEP VGTGNSAPTQ TSYQRRDTPT 
    LRSAAKQHYL KHSRYLPGIS IRNGILSNPG KEFIPPNPWS SSGLSGKSSG TMSVISKVNS 
    VGSSSTSSSG LTGNYVPSFL KKEIGSAMQR VHLAPIPDPS PGYSSLKAMR PHPGRPFFHT 
    QPRSTPGLIP RPPAAQPVHG RTDWASKYAS RR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.