Details for: NLGN1

Gene ID: 22871

Symbol: NLGN1

Ensembl ID: ENSG00000169760

Description: neuroligin 1

Associated with

Other Information

Genular Protein ID: 2558880954

Symbol: NLGN1_HUMAN

Name: Neuroligin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 20034102

Title: Characterization of the neuroligin gene family expression and evolution in zebrafish.

PubMed ID: 20034102

DOI: 10.1002/dvdy.22196

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 9278515

Title: Binding of neuroligins to PSD-95.

PubMed ID: 9278515

DOI: 10.1126/science.277.5331.1511

PubMed ID: 16882988

Title: Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin.

PubMed ID: 16882988

DOI: 10.1110/ps.062087506

PubMed ID: 18755801

Title: Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion.

PubMed ID: 18755801

DOI: 10.1210/en.2008-0274

PubMed ID: 19926856

Title: The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions.

PubMed ID: 19926856

DOI: 10.1073/pnas.0809510106

PubMed ID: 28841651

Title: Functional significance of rare neuroligin 1 variants found in autism.

PubMed ID: 28841651

DOI: 10.1371/journal.pgen.1006940

PubMed ID: 28972980

Title: Correction: Functional significance of rare neuroligin 1 variants found in autism.

PubMed ID: 28972980

DOI: 10.1371/journal.pgen.1007035

PubMed ID: 30460678

Title: A novel nonsense homozygous variant in the NLGN1 gene found in a pair of monozygotic twin brothers with intellectual disability and autism.

PubMed ID: 30460678

DOI: 10.1111/cge.13466

Sequence Information:

  • Length: 863
  • Mass: 96368
  • Checksum: FDF64A8325A075E2
  • Sequence:
  • MALPRCTWPN YVWRAVMACL VHRGLGAPLT LCMLGCLLQA GHVLSQKLDD VDPLVATNFG 
    KIRGIKKELN NEILGPVIQF LGVPYAAPPT GERRFQPPEP PSPWSDIRNA TQFAPVCPQN 
    IIDGRLPEVM LPVWFTNNLD VVSSYVQDQS EDCLYLNIYV PTEDVKRISK ECARKPGKKI 
    CRKGGPLTKK QTDDLGDNDG AEDEDIRDSG GPKPVMVYIH GGSYMEGTGN LYDGSVLASY 
    GNVIVITVNY RLGVLGFLST GDQAAKGNYG LLDLIQALRW TSENIGFFGG DPLRITVFGS 
    GAGGSCVNLL TLSHYSEGNR WSNSTKGLFQ RAIAQSGTAL SSWAVSFQPA KYARMLATKV 
    GCNVSDTVEL VECLQKKPYK ELVDQDIQPA RYHIAFGPVI DGDVIPDDPQ ILMEQGEFLN 
    YDIMLGVNQG EGLKFVENIV DSDDGISASD FDFAVSNFVD NLYGYPEGKD VLRETIKFMY 
    TDWADRHNPE TRRKTLLALF TDHQWVAPAV ATADLHSNFG SPTYFYAFYH HCQTDQVPAW 
    ADAAHGDEVP YVLGIPMIGP TELFPCNFSK NDVMLSAVVM TYWTNFAKTG DPNQPVPQDT 
    KFIHTKPNRF EEVAWTRYSQ KDQLYLHIGL KPRVKEHYRA NKVNLWLELV PHLHNLNDIS 
    QYTSTTTKVP STDITFRPTR KNSVPVTSAF PTAKQDDPKQ QPSPFSVDQR DYSTELSVTI 
    AVGASLLFLN ILAFAALYYK KDKRRHDVHR RCSPQRTTTN DLTHAQEEEI MSLQMKHTDL 
    DHECESIHPH EVVLRTACPP DYTLAMRRSP DDVPLMTPNT ITMIPNTIPG IQPLHTFNTF 
    TGGQNNTLPH PHPHPHSHST TRV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.