Details for: ENPP4

Gene ID: 22875

Symbol: ENPP4

Ensembl ID: ENSG00000001561

Description: ectonucleotide pyrophosphatase/phosphodiesterase 4

Associated with

Other Information

Genular Protein ID: 203481616

Symbol: ENPP4_HUMAN

Name: Bis(5'-adenosyl)-triphosphatase ENPP4

UniProtKB Accession Codes:

Q9Y6X5 A8K5G1 Q7L2N1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 13 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 4 EPD 1 Ensembl 1 GO 9 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11027689

Title: Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases.

PubMed ID: 11027689

DOI: 10.1074/jbc.m007552200

PubMed ID: 22995898

Title: NPP4 is a procoagulant enzyme on the surface of vascular endothelium.

PubMed ID: 22995898

DOI: 10.1182/blood-2012-04-425215

PubMed ID: 24338010

Title: The molecular basis of purinergic signal metabolism by ecto-nucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.

PubMed ID: 24338010

DOI: 10.1074/jbc.m113.505867

Sequence Information:

  • Length: 453
  • Mass: 51641
  • Checksum: BC82FA36D9B587C4
  • Sequence:
    • MKLLVILLFS GLITGFRSDS SSSLPPKLLL VSFDGFRADY LKNYEFPHLQ NFIKEGVLVE 
HVKNVFITKT FPNHYSIVTG LYEESHGIVA NSMYDAVTKK HFSDSNDKDP FWWNEAVPIW 
VTNQLQENRS SAAAMWPGTD VPIHDTISSY FMNYNSSVSF EERLNNITMW LNNSNPPVTF 
ATLYWEEPDA SGHKYGPEDK ENMSRVLKKI DDLIGDLVQR LKMLGLWENL NVIITSDHGM 
TQCSQDRLIN LDSCIDHSYY TLIDLSPVAA ILPKINRTEV YNKLKNCSPH MNVYLKEDIP 
NRFYYQHNDR IQPIILVADE GWTIVLNESS QKLGDHGYDN SLPSMHPFLA AHGPAFHKGY 
KHSTINIVDI YPMMCHILGL KPHPNNGTFG HTKCLLVDQW CINLPEAIAI VIGSLLVLTM 
LTCLIIIMQN RLSVPRPFSR LQLQEDDDDP LIG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.