Details for: INPP5F

Gene ID: 22876

Symbol: INPP5F

Ensembl ID: ENSG00000198825

Description: inositol polyphosphate-5-phosphatase F

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 3.84
    Marker Score: 15,998
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.6
    Marker Score: 12,010
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.33
    Marker Score: 1,365
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.22
    Marker Score: 44,188
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.21
    Marker Score: 84,022
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.17
    Marker Score: 2,708
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.07
    Marker Score: 8,579
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.05
    Marker Score: 75,807
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2
    Marker Score: 29,903
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.99
    Marker Score: 15,253
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.97
    Marker Score: 18,540
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.88
    Marker Score: 7,255
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.79
    Marker Score: 110,010
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.76
    Marker Score: 37,563
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.69
    Marker Score: 17,463
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.69
    Marker Score: 16,050
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.66
    Marker Score: 14,244
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.65
    Marker Score: 6,726
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.49
    Marker Score: 2,301
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.49
    Marker Score: 7,997
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,455
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.44
    Marker Score: 2,066
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.42
    Marker Score: 1,781
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.38
    Marker Score: 580
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.35
    Marker Score: 45,630
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.31
    Marker Score: 1,449
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.28
    Marker Score: 6,715
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.28
    Marker Score: 373
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.26
    Marker Score: 827
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.23
    Marker Score: 2,905
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.19
    Marker Score: 343
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.18
    Marker Score: 8,861
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.17
    Marker Score: 451
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.17
    Marker Score: 679
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.16
    Marker Score: 18,084
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.12
    Marker Score: 2,682
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.11
    Marker Score: 2,550
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.07
    Marker Score: 639
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 1.04
    Marker Score: 3,494
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.04
    Marker Score: 335
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.04
    Marker Score: 284
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.03
    Marker Score: 1,455
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.01
    Marker Score: 925
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,746
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,971
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.98
    Marker Score: 1,993
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,399
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,404
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.94
    Marker Score: 1,919
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 486
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 0.94
    Marker Score: 1,057
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 440
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.91
    Marker Score: 512
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.91
    Marker Score: 286
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,719
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.89
    Marker Score: 458
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.88
    Marker Score: 424
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,295
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4,961
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 311
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.86
    Marker Score: 273
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.82
    Marker Score: 876
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.81
    Marker Score: 280
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.8
    Marker Score: 198
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.8
    Marker Score: 480
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.79
    Marker Score: 913
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 0.79
    Marker Score: 266
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.79
    Marker Score: 459
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.78
    Marker Score: 377
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 0.78
    Marker Score: 736
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.78
    Marker Score: 312
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.78
    Marker Score: 384
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,260
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 580
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.76
    Marker Score: 2,249
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.76
    Marker Score: 936
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.75
    Marker Score: 4,479
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.73
    Marker Score: 635
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 378
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.72
    Marker Score: 3,017
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.72
    Marker Score: 774
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.71
    Marker Score: 241
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.7
    Marker Score: 2,945
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.69
    Marker Score: 1,578
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.68
    Marker Score: 340
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.68
    Marker Score: 624
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.68
    Marker Score: 1,420
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.67
    Marker Score: 322
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.67
    Marker Score: 816
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.67
    Marker Score: 1,282
  • Cell Name: PP cell (CL0000696)
    Fold Change: 0.66
    Marker Score: 149
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.66
    Marker Score: 230
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.66
    Marker Score: 413
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.66
    Marker Score: 525
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.65
    Marker Score: 1,103
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.64
    Marker Score: 285
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.63
    Marker Score: 716
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.61
    Marker Score: 543
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.61
    Marker Score: 220

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Inositol polyphosphate-5-phosphatase activity**: INPP5F is a phosphatase enzyme that catalyzes the dephosphorylation of inositol polyphosphates, which are key signaling molecules involved in various cellular processes. 2. **Expression in specific cell types**: INPP5F is specifically expressed in GABAergic neurons, inhibitory interneurons, cardiac neurons, and secondary lens fibers, suggesting its role in regulating neuronal function and development. 3. **Regulation of signaling pathways**: INPP5F has been implicated in the regulation of various signaling pathways, including the phosphatidylinositol 3-kinase/protein kinase B signal transduction pathway. 4. **Negative regulation of axon regeneration**: INPP5F has been shown to negatively regulate axon regeneration, suggesting its role in the regulation of neuronal development and function. **Pathways and Functions** 1. **Phosphatidylinositol-mediated signaling**: INPP5F is involved in the regulation of phosphatidylinositol-mediated signaling, which is a key pathway involved in various cellular processes, including cell growth, differentiation, and survival. 2. **Endocytosis and recycling**: INPP5F is involved in the regulation of endocytic recycling, which is the process by which cells recycle endocytosed molecules back to the plasma membrane. 3. **Metabolism of lipids**: INPP5F has been implicated in the regulation of lipid metabolism, which is essential for the proper functioning of cells. 4. **Regulation of cell motility**: INPP5F has been shown to regulate cell motility, which is essential for various cellular processes, including migration and invasion. **Clinical Significance** 1. **Neurological disorders**: INPP5F has been implicated in various neurological disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). 2. **Cardiac muscle hypertrophy**: INPP5F has been shown to regulate cardiac muscle hypertrophy in response to stress, suggesting its role in the regulation of cardiac function. 3. **Metabolic disorders**: INPP5F has been implicated in various metabolic disorders, including type 2 diabetes and obesity. 4. **Cancer**: INPP5F has been shown to regulate cancer cell growth and survival, suggesting its role in cancer development and progression. In conclusion, the INPP5F gene plays a crucial role in regulating various cellular processes, including signaling pathways, endocytosis, and metabolism. Its specific expression in GABAergic neurons, inhibitory interneurons, cardiac neurons, and secondary lens fibers suggests its involvement in the regulation of neuronal function and development. Further studies are needed to fully understand the clinical significance of INPP5F and its role in various diseases.

Genular Protein ID: 3648843473

Symbol: SAC2_HUMAN

Name: Sac domain-containing inositol phosphatase 2

UniProtKB Accession Codes:

Q9Y2H2 B3KRF1 D3DRD1 Q2T9J4 Q5W135 Q5W136 Q6NVY2 Q86U97 Q9H3D9 Q9NT51

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChEBI 4 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 ELM 1 EMBL 15 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 31 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 1 SABIO-RK 1 SAM 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11274189

Title: Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase.

PubMed ID: 11274189

DOI: 10.1074/jbc.m101579200

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 17322895

Title: Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.

PubMed ID: 17322895

DOI: 10.1038/nm1552

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25476455

Title: Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.

PubMed ID: 25476455

DOI: 10.1038/srep07330

PubMed ID: 25869668

Title: Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.

PubMed ID: 25869668

DOI: 10.1083/jcb.201409064

PubMed ID: 26203138

Title: Gene-silencing screen for mammalian axon regeneration identifies Inpp5f (Sac2) as an endogenous suppressor of repair after spinal cord injury.

PubMed ID: 26203138

DOI: 10.1523/jneurosci.1718-15.2015

PubMed ID: 25869669

Title: Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling.

PubMed ID: 25869669

DOI: 10.1083/jcb.201408027

Sequence Information:

  • Length: 1132
  • Mass: 128407
  • Checksum: 853719FC0AD455CD
  • Sequence:
    • MELFQAKDHY ILQQGERALW CSRRDGGLQL RPATDLLLAW NPICLGLVEG VIGKIQLHSD 
LPWWLILIRQ KALVGKLPGD HEVCKVTKIA VLSLSEMEPQ DLELELCKKH HFGINKPEKI 
IPSPDDSKFL LKTFTHIKSN VSAPNKKKVK ESKEKEKLER RLLEELLKMF MDSESFYYSL 
TYDLTNSVQR QSTGERDGRP LWQKVDDRFF WNKYMIQDLT EIGTPDVDFW IIPMIQGFVQ 
IEELVVNYTE SSDDEKSSPE TPPQESTCVD DIHPRFLVAL ISRRSRHRAG MRYKRRGVDK 
NGNVANYVET EQLIHVHNHT LSFVQTRGSV PVFWSQVGYR YNPRPRLDRS EKETVAYFCA 
HFEEQLNIYK KQVIINLVDQ AGREKIIGDA YLKQVLLFNN SHLTYVSFDF HEHCRGMKFE 
NVQTLTDAIY DIILDMKWCW VDEAGVICKQ EGIFRVNCMD CLDRTNVVQA AIARVVMEQQ 
LKKLGVMPPE QPLPVKCNRI YQIMWANNGD SISRQYAGTA ALKGDFTRTG ERKLAGVMKD 
GVNSANRYYL NRFKDAYRQA VIDLMQGIPV TEDLYSIFTK EKEHEALHKE NQRSHQELIS 
QLLQSYMKLL LPDDEKFHGG WALIDCDPSL IDATHRDVDV LLLLSNSAYY VAYYDDEVDK 
VNQYQRLSLE NLEKIEIGPE PTLFGKPKFS CMRLHYRYKE ASGYFHTLRA VMRNPEEDGK 
DTLQCIAEML QITKQAMGSD LPIIEKKLER KSSKPHEDII GIRSQNQGSL AQGKNFLMSK 
FSSLNQKVKQ TKSNVNIGNL RKLGNFTKPE MKVNFLKPNL KVNLWKSDSS LETMENTGVM 
DKVQAESDGD MSSDNDSYHS DEFLTNSKSD EDRQLANSLE SVGPIDYVLP SCGIIASAPR 
LGSRSQSLSS TDSSVHAPSE ITVAHGSGLG KGQESPLKKS PSAGDVHILT GFAKPMDIYC 
HRFVQDAQNK VTHLSETRSV SQQASQERNQ MTNQVSNETQ SESTEQTPSR PSQLDVSLSA 
TGPQFLSVEP AHSVASQKTP TSASSMLELE TGLHVTPSPS ESSSSRAVSP FAKIRSSMVQ 
VASITQAGLT HGINFAVSKV QKSPPEPEII NQVQQNELKK MFIQCQTRII QI

Genular Protein ID: 1694505555

Symbol: A0A3B3ITL0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A3B3ITL0

Database IDs:

Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 3 GO 3 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 Pfam 2 Proteomes 2 RefSeq 4 SAM 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1036
  • Mass: 117600
  • Checksum: 115E7C675837B4A1
  • Sequence:
    • MEPQDLELEL CKKHHFGINK PEKIIPSPDD SKFLLKTFTH IKSNVSAPNK KKVKESKEKE 
KLERRLLEEL LKMFMDSESF YYSLTYDLTN SVQRQSTGER DGRPLWQKVD DRFFWNKYMI 
QDLTEIGTPD VDFWIIPMIQ GFVQIEELVV NYTESSDDEK SSPETPPQES TCVDDIHPRF 
LVALISRRSR HRAGMRYKRR GVDKNGNVAN YVETEQLIHV HNHTLSFVQT RGSVPVFWSQ 
VGYRYNPRPR LDRSEKETVA YFCAHFEEQL NIYKKQVIIN LVDQAGREKI IGDAYLKQVL 
LFNNSHLTYV SFDFHEHCRG MKFENVQTLT DAIYDIILDM KWCWVDEAGV ICKQEGIFRV 
NCMDCLDRTN VVQAAIARVV MEQQLKKLGV MPPEQPLPVK CNRIYQIMWA NNGDSISRQY 
AGTAALKGDF TRTGERKLAG VMKDGVNSAN RYYLNRFKDA YRQAVIDLMQ GIPVTEDLYS 
IFTKEKEHEA LHKENQRSHQ ELISQLLQSY MKLLLPDDEK FHGGWALIDC DPSLIDATHR 
DVDVLLLLSN SAYYVAYYDD EVDKVNQYQR LSLENLEKIE IGPEPTLFGK PKFSCMRLHY 
RYKEASGYFH TLRAVMRNPE EDGKDTLQCI AEMLQITKQA MGSDLPIIEK KLERKSSKPH 
EDIIGIRSQN QGSLAQGKNF LMSKFSSLNQ KVKQTKSNVN IGNLRKLGNF TKPEMKVNFL 
KPNLKVNLWK SDSSLETMEN TGVMDKVQAE SDGDMSSDND SYHSDEFLTN SKSDEDRQLA 
NSLESVGPID YVLPSCGIIA SAPRLGSRSQ SLSSTDSSVH APSEITVAHG SGLGKGQESP 
LKKSPSAGDV HILTGFAKPM DIYCHRFVQD AQNKVTHLSE TRSVSQQASQ ERNQMTNQVS 
NETQSESTEQ TPSRPSQLDV SLSATGPQFL SVEPAHSVAS QKTPTSASSM LELETGLHVT 
PSPSESSSSR AVSPFAKIRS SMVQVASITQ AGLTHGINFA VSKVQKSPPE PEIINQVQQN 
ELKKMFIQCQ TRIIQI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.