Details for: INPP5F
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: GABAergic neuron (CL0000617)
Fold Change: 3.84
Marker Score: 15,998 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.6
Marker Score: 12,010 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.33
Marker Score: 1,365 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.22
Marker Score: 44,188 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.21
Marker Score: 84,022 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.17
Marker Score: 2,708 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.07
Marker Score: 8,579 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.05
Marker Score: 75,807 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2
Marker Score: 29,903 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.99
Marker Score: 15,253 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.97
Marker Score: 18,540 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.88
Marker Score: 7,255 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.79
Marker Score: 110,010 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.76
Marker Score: 37,563 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.69
Marker Score: 17,463 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.69
Marker Score: 16,050 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.66
Marker Score: 14,244 - Cell Name: neuron (CL0000540)
Fold Change: 1.65
Marker Score: 6,726 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.49
Marker Score: 2,301 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.49
Marker Score: 7,997 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,455 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.44
Marker Score: 2,066 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.42
Marker Score: 1,781 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.38
Marker Score: 580 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.35
Marker Score: 45,630 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.31
Marker Score: 1,449 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.28
Marker Score: 6,715 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.28
Marker Score: 373 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.26
Marker Score: 827 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.23
Marker Score: 2,905 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.19
Marker Score: 343 - Cell Name: granule cell (CL0000120)
Fold Change: 1.18
Marker Score: 8,861 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.17
Marker Score: 451 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.17
Marker Score: 679 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.16
Marker Score: 18,084 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.12
Marker Score: 2,682 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.11
Marker Score: 2,550 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.07
Marker Score: 639 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.04
Marker Score: 3,494 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.04
Marker Score: 335 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.04
Marker Score: 284 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.03
Marker Score: 1,455 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.01
Marker Score: 925 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,746 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,971 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.98
Marker Score: 1,993 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,399 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,404 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.94
Marker Score: 1,919 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 486 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.94
Marker Score: 1,057 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 440 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.91
Marker Score: 512 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.91
Marker Score: 286 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,719 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.89
Marker Score: 458 - Cell Name: neural cell (CL0002319)
Fold Change: 0.88
Marker Score: 424 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.87
Marker Score: 4,961 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 311 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.86
Marker Score: 273 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.82
Marker Score: 876 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.81
Marker Score: 280 - Cell Name: oocyte (CL0000023)
Fold Change: 0.8
Marker Score: 198 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.8
Marker Score: 480 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.79
Marker Score: 913 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.79
Marker Score: 266 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.79
Marker Score: 459 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 0.78
Marker Score: 377 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.78
Marker Score: 736 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.78
Marker Score: 312 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.78
Marker Score: 384 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,260 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 580 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.76
Marker Score: 2,249 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.76
Marker Score: 936 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.75
Marker Score: 4,479 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.73
Marker Score: 635 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 378 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.72
Marker Score: 3,017 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.72
Marker Score: 774 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.71
Marker Score: 241 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.7
Marker Score: 2,945 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.69
Marker Score: 1,578 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.68
Marker Score: 340 - Cell Name: brush cell (CL0002204)
Fold Change: 0.68
Marker Score: 624 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.68
Marker Score: 1,420 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.67
Marker Score: 322 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.67
Marker Score: 816 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 172 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.67
Marker Score: 1,282 - Cell Name: PP cell (CL0000696)
Fold Change: 0.66
Marker Score: 149 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.66
Marker Score: 230 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.66
Marker Score: 413 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.66
Marker Score: 525 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.65
Marker Score: 1,103 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.64
Marker Score: 285 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.63
Marker Score: 716 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.61
Marker Score: 543 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.61
Marker Score: 220
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3648843473
Symbol: SAC2_HUMAN
Name: Sac domain-containing inositol phosphatase 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11274189
Title: Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase.
PubMed ID: 11274189
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 17322895
Title: Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.
PubMed ID: 17322895
DOI: 10.1038/nm1552
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25476455
Title: Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.
PubMed ID: 25476455
DOI: 10.1038/srep07330
PubMed ID: 25869668
Title: Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.
PubMed ID: 25869668
PubMed ID: 26203138
Title: Gene-silencing screen for mammalian axon regeneration identifies Inpp5f (Sac2) as an endogenous suppressor of repair after spinal cord injury.
PubMed ID: 26203138
PubMed ID: 25869669
Title: Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling.
PubMed ID: 25869669
Sequence Information:
- Length: 1132
- Mass: 128407
- Checksum: 853719FC0AD455CD
- Sequence:
MELFQAKDHY ILQQGERALW CSRRDGGLQL RPATDLLLAW NPICLGLVEG VIGKIQLHSD LPWWLILIRQ KALVGKLPGD HEVCKVTKIA VLSLSEMEPQ DLELELCKKH HFGINKPEKI IPSPDDSKFL LKTFTHIKSN VSAPNKKKVK ESKEKEKLER RLLEELLKMF MDSESFYYSL TYDLTNSVQR QSTGERDGRP LWQKVDDRFF WNKYMIQDLT EIGTPDVDFW IIPMIQGFVQ IEELVVNYTE SSDDEKSSPE TPPQESTCVD DIHPRFLVAL ISRRSRHRAG MRYKRRGVDK NGNVANYVET EQLIHVHNHT LSFVQTRGSV PVFWSQVGYR YNPRPRLDRS EKETVAYFCA HFEEQLNIYK KQVIINLVDQ AGREKIIGDA YLKQVLLFNN SHLTYVSFDF HEHCRGMKFE NVQTLTDAIY DIILDMKWCW VDEAGVICKQ EGIFRVNCMD CLDRTNVVQA AIARVVMEQQ LKKLGVMPPE QPLPVKCNRI YQIMWANNGD SISRQYAGTA ALKGDFTRTG ERKLAGVMKD GVNSANRYYL NRFKDAYRQA VIDLMQGIPV TEDLYSIFTK EKEHEALHKE NQRSHQELIS QLLQSYMKLL LPDDEKFHGG WALIDCDPSL IDATHRDVDV LLLLSNSAYY VAYYDDEVDK VNQYQRLSLE NLEKIEIGPE PTLFGKPKFS CMRLHYRYKE ASGYFHTLRA VMRNPEEDGK DTLQCIAEML QITKQAMGSD LPIIEKKLER KSSKPHEDII GIRSQNQGSL AQGKNFLMSK FSSLNQKVKQ TKSNVNIGNL RKLGNFTKPE MKVNFLKPNL KVNLWKSDSS LETMENTGVM DKVQAESDGD MSSDNDSYHS DEFLTNSKSD EDRQLANSLE SVGPIDYVLP SCGIIASAPR LGSRSQSLSS TDSSVHAPSE ITVAHGSGLG KGQESPLKKS PSAGDVHILT GFAKPMDIYC HRFVQDAQNK VTHLSETRSV SQQASQERNQ MTNQVSNETQ SESTEQTPSR PSQLDVSLSA TGPQFLSVEP AHSVASQKTP TSASSMLELE TGLHVTPSPS ESSSSRAVSP FAKIRSSMVQ VASITQAGLT HGINFAVSKV QKSPPEPEII NQVQQNELKK MFIQCQTRII QI
Genular Protein ID: 1694505555
Symbol: A0A3B3ITL0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1036
- Mass: 117600
- Checksum: 115E7C675837B4A1
- Sequence:
MEPQDLELEL CKKHHFGINK PEKIIPSPDD SKFLLKTFTH IKSNVSAPNK KKVKESKEKE KLERRLLEEL LKMFMDSESF YYSLTYDLTN SVQRQSTGER DGRPLWQKVD DRFFWNKYMI QDLTEIGTPD VDFWIIPMIQ GFVQIEELVV NYTESSDDEK SSPETPPQES TCVDDIHPRF LVALISRRSR HRAGMRYKRR GVDKNGNVAN YVETEQLIHV HNHTLSFVQT RGSVPVFWSQ VGYRYNPRPR LDRSEKETVA YFCAHFEEQL NIYKKQVIIN LVDQAGREKI IGDAYLKQVL LFNNSHLTYV SFDFHEHCRG MKFENVQTLT DAIYDIILDM KWCWVDEAGV ICKQEGIFRV NCMDCLDRTN VVQAAIARVV MEQQLKKLGV MPPEQPLPVK CNRIYQIMWA NNGDSISRQY AGTAALKGDF TRTGERKLAG VMKDGVNSAN RYYLNRFKDA YRQAVIDLMQ GIPVTEDLYS IFTKEKEHEA LHKENQRSHQ ELISQLLQSY MKLLLPDDEK FHGGWALIDC DPSLIDATHR DVDVLLLLSN SAYYVAYYDD EVDKVNQYQR LSLENLEKIE IGPEPTLFGK PKFSCMRLHY RYKEASGYFH TLRAVMRNPE EDGKDTLQCI AEMLQITKQA MGSDLPIIEK KLERKSSKPH EDIIGIRSQN QGSLAQGKNF LMSKFSSLNQ KVKQTKSNVN IGNLRKLGNF TKPEMKVNFL KPNLKVNLWK SDSSLETMEN TGVMDKVQAE SDGDMSSDND SYHSDEFLTN SKSDEDRQLA NSLESVGPID YVLPSCGIIA SAPRLGSRSQ SLSSTDSSVH APSEITVAHG SGLGKGQESP LKKSPSAGDV HILTGFAKPM DIYCHRFVQD AQNKVTHLSE TRSVSQQASQ ERNQMTNQVS NETQSESTEQ TPSRPSQLDV SLSATGPQFL SVEPAHSVAS QKTPTSASSM LELETGLHVT PSPSESSSSR AVSPFAKIRS SMVQVASITQ AGLTHGINFA VSKVQKSPPE PEIINQVQQN ELKKMFIQCQ TRIIQI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.