Details for: INPP5F

Gene ID: 22876

Symbol: INPP5F

Ensembl ID: ENSG00000198825

Description: inositol polyphosphate-5-phosphatase F

Associated with

Other Information

Genular Protein ID: 3648843473

Symbol: SAC2_HUMAN

Name: Sac domain-containing inositol phosphatase 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11274189

Title: Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase.

PubMed ID: 11274189

DOI: 10.1074/jbc.m101579200

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 17322895

Title: Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.

PubMed ID: 17322895

DOI: 10.1038/nm1552

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25476455

Title: Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.

PubMed ID: 25476455

DOI: 10.1038/srep07330

PubMed ID: 25869668

Title: Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.

PubMed ID: 25869668

DOI: 10.1083/jcb.201409064

PubMed ID: 26203138

Title: Gene-silencing screen for mammalian axon regeneration identifies Inpp5f (Sac2) as an endogenous suppressor of repair after spinal cord injury.

PubMed ID: 26203138

DOI: 10.1523/jneurosci.1718-15.2015

PubMed ID: 25869669

Title: Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling.

PubMed ID: 25869669

DOI: 10.1083/jcb.201408027

Sequence Information:

  • Length: 1132
  • Mass: 128407
  • Checksum: 853719FC0AD455CD
  • Sequence:
  • MELFQAKDHY ILQQGERALW CSRRDGGLQL RPATDLLLAW NPICLGLVEG VIGKIQLHSD 
    LPWWLILIRQ KALVGKLPGD HEVCKVTKIA VLSLSEMEPQ DLELELCKKH HFGINKPEKI 
    IPSPDDSKFL LKTFTHIKSN VSAPNKKKVK ESKEKEKLER RLLEELLKMF MDSESFYYSL 
    TYDLTNSVQR QSTGERDGRP LWQKVDDRFF WNKYMIQDLT EIGTPDVDFW IIPMIQGFVQ 
    IEELVVNYTE SSDDEKSSPE TPPQESTCVD DIHPRFLVAL ISRRSRHRAG MRYKRRGVDK 
    NGNVANYVET EQLIHVHNHT LSFVQTRGSV PVFWSQVGYR YNPRPRLDRS EKETVAYFCA 
    HFEEQLNIYK KQVIINLVDQ AGREKIIGDA YLKQVLLFNN SHLTYVSFDF HEHCRGMKFE 
    NVQTLTDAIY DIILDMKWCW VDEAGVICKQ EGIFRVNCMD CLDRTNVVQA AIARVVMEQQ 
    LKKLGVMPPE QPLPVKCNRI YQIMWANNGD SISRQYAGTA ALKGDFTRTG ERKLAGVMKD 
    GVNSANRYYL NRFKDAYRQA VIDLMQGIPV TEDLYSIFTK EKEHEALHKE NQRSHQELIS 
    QLLQSYMKLL LPDDEKFHGG WALIDCDPSL IDATHRDVDV LLLLSNSAYY VAYYDDEVDK 
    VNQYQRLSLE NLEKIEIGPE PTLFGKPKFS CMRLHYRYKE ASGYFHTLRA VMRNPEEDGK 
    DTLQCIAEML QITKQAMGSD LPIIEKKLER KSSKPHEDII GIRSQNQGSL AQGKNFLMSK 
    FSSLNQKVKQ TKSNVNIGNL RKLGNFTKPE MKVNFLKPNL KVNLWKSDSS LETMENTGVM 
    DKVQAESDGD MSSDNDSYHS DEFLTNSKSD EDRQLANSLE SVGPIDYVLP SCGIIASAPR 
    LGSRSQSLSS TDSSVHAPSE ITVAHGSGLG KGQESPLKKS PSAGDVHILT GFAKPMDIYC 
    HRFVQDAQNK VTHLSETRSV SQQASQERNQ MTNQVSNETQ SESTEQTPSR PSQLDVSLSA 
    TGPQFLSVEP AHSVASQKTP TSASSMLELE TGLHVTPSPS ESSSSRAVSP FAKIRSSMVQ 
    VASITQAGLT HGINFAVSKV QKSPPEPEII NQVQQNELKK MFIQCQTRII QI

Genular Protein ID: 1694505555

Symbol: A0A3B3ITL0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1036
  • Mass: 117600
  • Checksum: 115E7C675837B4A1
  • Sequence:
  • MEPQDLELEL CKKHHFGINK PEKIIPSPDD SKFLLKTFTH IKSNVSAPNK KKVKESKEKE 
    KLERRLLEEL LKMFMDSESF YYSLTYDLTN SVQRQSTGER DGRPLWQKVD DRFFWNKYMI 
    QDLTEIGTPD VDFWIIPMIQ GFVQIEELVV NYTESSDDEK SSPETPPQES TCVDDIHPRF 
    LVALISRRSR HRAGMRYKRR GVDKNGNVAN YVETEQLIHV HNHTLSFVQT RGSVPVFWSQ 
    VGYRYNPRPR LDRSEKETVA YFCAHFEEQL NIYKKQVIIN LVDQAGREKI IGDAYLKQVL 
    LFNNSHLTYV SFDFHEHCRG MKFENVQTLT DAIYDIILDM KWCWVDEAGV ICKQEGIFRV 
    NCMDCLDRTN VVQAAIARVV MEQQLKKLGV MPPEQPLPVK CNRIYQIMWA NNGDSISRQY 
    AGTAALKGDF TRTGERKLAG VMKDGVNSAN RYYLNRFKDA YRQAVIDLMQ GIPVTEDLYS 
    IFTKEKEHEA LHKENQRSHQ ELISQLLQSY MKLLLPDDEK FHGGWALIDC DPSLIDATHR 
    DVDVLLLLSN SAYYVAYYDD EVDKVNQYQR LSLENLEKIE IGPEPTLFGK PKFSCMRLHY 
    RYKEASGYFH TLRAVMRNPE EDGKDTLQCI AEMLQITKQA MGSDLPIIEK KLERKSSKPH 
    EDIIGIRSQN QGSLAQGKNF LMSKFSSLNQ KVKQTKSNVN IGNLRKLGNF TKPEMKVNFL 
    KPNLKVNLWK SDSSLETMEN TGVMDKVQAE SDGDMSSDND SYHSDEFLTN SKSDEDRQLA 
    NSLESVGPID YVLPSCGIIA SAPRLGSRSQ SLSSTDSSVH APSEITVAHG SGLGKGQESP 
    LKKSPSAGDV HILTGFAKPM DIYCHRFVQD AQNKVTHLSE TRSVSQQASQ ERNQMTNQVS 
    NETQSESTEQ TPSRPSQLDV SLSATGPQFL SVEPAHSVAS QKTPTSASSM LELETGLHVT 
    PSPSESSSSR AVSPFAKIRS SMVQVASITQ AGLTHGINFA VSKVQKSPPE PEIINQVQQN 
    ELKKMFIQCQ TRIIQI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.