Details for: WDR37
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.05
Marker Score: 2,267 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2
Marker Score: 44,643 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.92
Marker Score: 28,681 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.87
Marker Score: 6,640 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.82
Marker Score: 111,980 - Cell Name: neuron (CL0000540)
Fold Change: 1.81
Marker Score: 7,362 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.8
Marker Score: 68,293 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.8
Marker Score: 35,717 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.79
Marker Score: 13,743 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.79
Marker Score: 65,880 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.78
Marker Score: 6,866 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.75
Marker Score: 16,582 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.72
Marker Score: 14,736 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.7
Marker Score: 16,021 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.7
Marker Score: 7,103 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.68
Marker Score: 3,681 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.65
Marker Score: 35,305 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.65
Marker Score: 6,850 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.63
Marker Score: 16,857 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.55
Marker Score: 905 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.54
Marker Score: 2,374 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.53
Marker Score: 641 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.46
Marker Score: 426 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.44
Marker Score: 458 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.4
Marker Score: 2,348 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.3
Marker Score: 1,572 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.25
Marker Score: 341 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.22
Marker Score: 5,643 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.22
Marker Score: 19,045 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.21
Marker Score: 601 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.18
Marker Score: 3,355 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.17
Marker Score: 367 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.17
Marker Score: 1,254 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.13
Marker Score: 2,665 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.12
Marker Score: 671 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.12
Marker Score: 653 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.11
Marker Score: 357 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.1
Marker Score: 1,479 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.09
Marker Score: 19,398 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.09
Marker Score: 1,232 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.07
Marker Score: 825 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.06
Marker Score: 634 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 1.04
Marker Score: 1,027 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.02
Marker Score: 1,960 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.01
Marker Score: 1,160 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1
Marker Score: 529 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1
Marker Score: 1,243 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,715 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,940 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.98
Marker Score: 513 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,395 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.96
Marker Score: 1,956 - Cell Name: fat cell (CL0000136)
Fold Change: 0.96
Marker Score: 535 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.95
Marker Score: 1,021 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,403 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 481 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 438 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,712 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.9
Marker Score: 1,908 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.9
Marker Score: 783 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.9
Marker Score: 259 - Cell Name: germ cell (CL0000586)
Fold Change: 0.88
Marker Score: 1,532 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.87
Marker Score: 349 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,929 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.86
Marker Score: 419 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 310 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.84
Marker Score: 303 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.84
Marker Score: 1,218 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.84
Marker Score: 1,184 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.84
Marker Score: 413 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.81
Marker Score: 5,204 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.8
Marker Score: 3,469 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.8
Marker Score: 273 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.79
Marker Score: 26,652 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.79
Marker Score: 249 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.78
Marker Score: 313 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.78
Marker Score: 964 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: podocyte (CL0000653)
Fold Change: 0.78
Marker Score: 288 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.77
Marker Score: 4,650 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 588 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.77
Marker Score: 1,837 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.75
Marker Score: 3,156 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.75
Marker Score: 280 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.75
Marker Score: 787 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 375 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.72
Marker Score: 618 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.71
Marker Score: 11,372 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.71
Marker Score: 272 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 0.7
Marker Score: 392 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.7
Marker Score: 285 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.7
Marker Score: 185 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.7
Marker Score: 2,479 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.69
Marker Score: 2,187 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.69
Marker Score: 251 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.68
Marker Score: 718 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 615 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.67
Marker Score: 213
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3207316607
Symbol: WDR37_HUMAN
Name: WD repeat-containing protein 37
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 31327508
Title: De novo variants in WDR37 are associated with epilepsy, colobomas, dysmorphism, developmental delay, intellectual disability, and cerebellar hypoplasia.
PubMed ID: 31327508
PubMed ID: 31491411
PubMed ID: 31327510
Title: De novo missense variants in WDR37 cause a severe multisystemic syndrome.
PubMed ID: 31327510
PubMed ID: 32530092
Title: Expanding the phenotypic spectrum consequent upon de novo WDR37 missense variants.
PubMed ID: 32530092
DOI: 10.1111/cge.13795
PubMed ID: 34642815
Title: WDR37 syndrome: identification of a distinct new cluster of disease-associated variants and functional analyses of mutant proteins.
PubMed ID: 34642815
Sequence Information:
- Length: 494
- Mass: 54665
- Checksum: 49D05A24DD230005
- Sequence:
MPTESASCST ARQTKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ KLKTTYKAST SKIVSSFKTT TSRAACQLVK EYIGHRDGIW DVSVAKTQPV VLGTASADHT ALLWSIETGK CLVKYAGHVG SVNSIKFHPS EQLALTASGD QTAHIWRYAV QLPTPQPVAD TSISGEDEVE CSDKDEPDLD GDVSSDCPTI RVPLTSLKSH QGVVIASDWL VGGKQAVTAS WDRTANLYDV ETSELVHSLT GHDQELTHCC THPTQRLVVT SSRDTTFRLW DFRDPSIHSV NVFQGHTDTV TSAVFTVGDN VVSGSDDRTV KVWDLKNMRS PIATIRTDSA INRINVCVGQ KIIALPHDNR QVRLFDMSGV RLARLPRSSR QGHRRMVCCS AWSEDHPVCN LFTCGFDRQA IGWNINIPAL LQEK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.