Details for: ZBTB1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.12
Marker Score: 2,436 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.85
Marker Score: 39,381 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.8
Marker Score: 776 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.78
Marker Score: 65,556 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 1.74
Marker Score: 2,407 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.72
Marker Score: 25,787 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.56
Marker Score: 6,462 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.5
Marker Score: 876 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.46
Marker Score: 4,083 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.43
Marker Score: 13,454 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.43
Marker Score: 54,314 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.42
Marker Score: 5,497 - Cell Name: neuron (CL0000540)
Fold Change: 1.42
Marker Score: 5,768 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.41
Marker Score: 14,600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.39
Marker Score: 13,244 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.39
Marker Score: 407 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.39
Marker Score: 11,936 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.37
Marker Score: 84,547 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.37
Marker Score: 2,636 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.36
Marker Score: 27,038 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.35
Marker Score: 2,086 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.34
Marker Score: 2,933 - Cell Name: podocyte (CL0000653)
Fold Change: 1.3
Marker Score: 482 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.29
Marker Score: 1,396 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 1.29
Marker Score: 399 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 1.25
Marker Score: 3,044 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.23
Marker Score: 9,432 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.22
Marker Score: 609 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.2
Marker Score: 5,004 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.18
Marker Score: 705 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 1.18
Marker Score: 1,735 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.18
Marker Score: 1,298 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.15
Marker Score: 672 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.15
Marker Score: 1,687 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.14
Marker Score: 664 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.1
Marker Score: 17,174 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.09
Marker Score: 1,319 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 1.07
Marker Score: 6,484 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 1.07
Marker Score: 873 - Cell Name: Unknown (CL0000548)
Fold Change: 1.06
Marker Score: 776 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.06
Marker Score: 974 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.05
Marker Score: 906 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.04
Marker Score: 505 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 1.03
Marker Score: 907 - Cell Name: preosteoblast (CL0007010)
Fold Change: 1.03
Marker Score: 292 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.01
Marker Score: 1,028 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 1.01
Marker Score: 3,194 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.01
Marker Score: 1,221 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 1
Marker Score: 604 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1
Marker Score: 1,417 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 1
Marker Score: 933 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,608 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,833 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.98
Marker Score: 488 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,378 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 0.98
Marker Score: 602 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.97
Marker Score: 211 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.97
Marker Score: 392 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.97
Marker Score: 231 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 0.96
Marker Score: 857 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.96
Marker Score: 1,198 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 0.96
Marker Score: 340 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.96
Marker Score: 805 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.96
Marker Score: 1,604 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.95
Marker Score: 1,038 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.95
Marker Score: 572 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.95
Marker Score: 546 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.95
Marker Score: 2,618 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.95
Marker Score: 305 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 0.94
Marker Score: 715 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.94
Marker Score: 1,336 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.94
Marker Score: 642 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.94
Marker Score: 352 - Cell Name: fat cell (CL0000136)
Fold Change: 0.94
Marker Score: 525 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,385 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.94
Marker Score: 296 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.93
Marker Score: 379 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 479 - Cell Name: basal cell (CL0000646)
Fold Change: 0.92
Marker Score: 1,190 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 435 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.92
Marker Score: 202 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.92
Marker Score: 1,231 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.91
Marker Score: 179 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 0.91
Marker Score: 613 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.91
Marker Score: 578 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.91
Marker Score: 314 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.9
Marker Score: 956 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.9
Marker Score: 903 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.9
Marker Score: 855 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,686 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 0.89
Marker Score: 1,866 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 0.89
Marker Score: 1,584 - Cell Name: germ cell (CL0000586)
Fold Change: 0.88
Marker Score: 1,543 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.88
Marker Score: 217 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.88
Marker Score: 3,775 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.88
Marker Score: 368 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.88
Marker Score: 306 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,293 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.87
Marker Score: 7,661 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.87
Marker Score: 261
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1653594502
Symbol: ZBTB1_HUMAN
Name: Zinc finger and BTB domain-containing protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20797634
Title: Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif.
PubMed ID: 20797634
PubMed ID: 21706167
Title: Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE.
PubMed ID: 21706167
PubMed ID: 22753936
Title: Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development.
PubMed ID: 22753936
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24657165
Title: Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis.
PubMed ID: 24657165
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 713
- Mass: 82016
- Checksum: 4B120DD45FA14305
- Sequence:
MAKPSHSSYV LQQLNNQREW GFLCDCCIAI DDIYFQAHKA VLAACSSYFR MFFMNHQHST AQLNLSNMKI SAECFDLILQ FMYLGKIMTA PSSFEQFKVA MNYLQLYNVP DCLEDIQDAD CSSSKCSSSA SSKQNSKMIF GVRMYEDTVA RNGNEANRWC AEPSSTVNTP HNREADEESL QLGNFPEPLF DVCKKSSVSK LSTPKERVSR RFGRSFTCDS CGFGFSCEKL LDEHVLTCTN RHLYQNTRSY HRIVDIRDGK DSNIKAEFGE KDSSKTFSAQ TDKYRGDTSQ AADDSASTTG SRKSSTVESE IASEEKSRAA ERKRIIIKME PEDIPTDELK DFNIIKVTDK DCNESTDNDE LEDEPEEPFY RYYVEEDVSI KKSGRKTLKP RMSVSADERG GLENMRPPNN SSPVQEDAEN ASCELCGLTI TEEDLSSHYL AKHIENICAC GKCGQILVKG RQLQEHAQRC GEPQDLTMNG LGNTEEKMDL EENPDEQSEI RDMFVEMLDD FRDNHYQINS IQKKQLFKHS ACPFRCPNCG QRFETENLVV EHMSSCLDQD MFKSAIMEEN ERDHRRKHFC NLCGKGFYQR CHLREHYTVH TKEKQFVCQT CGKQFLRERQ LRLHNDMHKG MARYVCSICD QGNFRKHDHV RHMISHLSAG ETICQVCFQI FPNNEQLEQH MDVHLYTCGI CGAKFNLRKD MRSHYNAKHL KRT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.